A Study on Hypothyroidism in a School for the Mentally Retarded in Bandung
Keywords:
hypothyroidism, debils, imbecils, debil-imbecil
Abstract
A study was made on 114 pupils from a school for the mentally retarded in Bandung. In 50 subjects the length ratio between the upper and the lower segment of the body were more than one; of 44 subjects (32 debils, 11 imbecils, 1 borderline debil-imbecil) we found 2 with hypertelorism, 1 with dry and rough skin, and 1 with gross and fine motor abnormalities. Dental development and bone ages were within normal limits. No rise in serum cholesterol and changes in NTR (Normalized Thyroxine Ratio) were found. T4 (thyroxine) values were within normal limits. Radioactive iodine uptake and scanning of 42 subjects showed hyperplasia in 32 and euthyroidism in 5 subjects. Three subjects suggested a possible iodine contamination, 2 subjects with uptake of more than 50%, one of them showed adenoma (toxic?) on scanning; on the other one scanning was not done. Hypothyroidism was not found; 32 subjects which showed hyperplasia were suggestive of active thyroid. Further studies should be done in another sample of population to trace the problems of hypothyroidism in childhood.References
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MEDEIROS-NETO, G.A.; DE ASSIS, L.M.; NICOLAU, W.; COELHO-NETO, A.S.; BLOISE, W.; LUTHOLD, W.; MONTENEGRO, J.L. and PIERONI, R.R. : Congenital and juvenile hypothyroidism due to thyroid dysgenesis. J. Nucl. Med. 6 : 275 (1915).
SILVER, H.K. and GOTLIN, R.W. : Endocrine disorders (thyroid) in Kempe's Current Pediatric Diagnosis and Treatment. 2nd ed., p. 602 (Lange med. Publ./Maruzen, Tokyo 1972).
VAN WYK, J.J. : The thyroid, in Barnett's Pediatrics, 15th ed. (Appleton Century Crofts, New York 1972).
WILKINS, L. : Thyroid (hormones and their actions); thyroid disorders in childhood and adolescence. 3rd ed., p. 73 (Thomas Publ., New York 1965).
WILROY, Jr., R.S. and CAMACHO, A.M. : Thyroid gland in Hughes' Synopsis of Pediatrics, 3rd ed., p. 548 (Mosby/Tappan, Tokyo 1971).
BOYD, W. : Textbook of pathology; structure and function in diseases. 7th ed. (Lea & Febiger, Philadelphia 1965).
CAFFEY, J. : Pediatric X-ray diagnostic. 6th ed. (Yearb. med. Publ., Chicago 1972).
CHOUFOER, J.C.; VAN RHIJN, M.; KASSENAAR, A.A.H. and QUIRIDO, A. : Endemic goiter in western New Guinea; II. Clinical picture, incidence and pathogenesis of endemic cretinism. J. clin. Endocrinol. 25 : 385 (1965). Cited by Djokomoeljanto, 1974.
DAVIES, A.G. : Thyroid physiology. Br. med. J. 2 : 206 (1972).
DI GEORGE, A.M. : Disorders of the thyroid gland; in Nelson's Textbook of Pediatrics, 10th ed., p. 1301 (Saunders/Igaku Shoin, Philadelphia/London/Tokyo 1975).
DJOKOMOELJANTO, R.R.J.S. : The effect of severe iodine deficiency; a study on a population in Central Java, Indonesia. Thesis, Semarang (1974).
DJUMADIAS, A.N.; DRADJAT PRAWIRANEGARA and LUBIS, B.A. : Height and weight of healthy Indonesian school children and youth. Nutrition Institute, Department of Health, Indonesia, Jakarta (1964).
DUSSAULT, J.H.; COULOMBE, P.; LABERGE, C.F.; LETARTE, J.; GUYDA, H. and. KHOURY, K. : Preliminary report on a mass screening program for neonatal hypothyroidism, J. Pediatr. 86 : 670 (1975).
FRANKENBURG, W.K. and DODDS, J.B. : The Denver developmental screening test. J. Pediatr. 71 ; 181 (1967). Cited by Vaughan and McKay, 1975.
FRANKENBURG, W.K.; GOLDSTEIN, A.D. and CAMP, B.W. : The revised Denver developmental screening test; its accuracy as a screening instrument. J. Pediatr. 79 : 988 (1971). Cited by Vaughan and McKay, 1975.
12. HUTCHINSON, J.H. : Hypothyroidism in practical problems. 2nd ed. (Yearb. med. Publ., Chicago 1967).
LUHULIMA, L.F. : Is the thyroid-sex hormones functional interrelation more sensitive to goiter producing agents in females than in males? An analysis of 1.253 cases. First Asia and Oceania Congr. Nucl. med., Sydney, September 1976.
MEDEIROS-NETO, G.A.; DE ASSIS, L.M.; NICOLAU, W.; COELHO-NETO, A.S.; BLOISE, W.; LUTHOLD, W.; MONTENEGRO, J.L. and PIERONI, R.R. : Congenital and juvenile hypothyroidism due to thyroid dysgenesis. J. Nucl. Med. 6 : 275 (1915).
SILVER, H.K. and GOTLIN, R.W. : Endocrine disorders (thyroid) in Kempe's Current Pediatric Diagnosis and Treatment. 2nd ed., p. 602 (Lange med. Publ./Maruzen, Tokyo 1972).
VAN WYK, J.J. : The thyroid, in Barnett's Pediatrics, 15th ed. (Appleton Century Crofts, New York 1972).
WILKINS, L. : Thyroid (hormones and their actions); thyroid disorders in childhood and adolescence. 3rd ed., p. 73 (Thomas Publ., New York 1965).
WILROY, Jr., R.S. and CAMACHO, A.M. : Thyroid gland in Hughes' Synopsis of Pediatrics, 3rd ed., p. 548 (Mosby/Tappan, Tokyo 1971).
Published
2017-06-13
How to Cite
1.
Asikin J, Dibjosubroto S, Pallencaoe A, Luhulima L. A Study on Hypothyroidism in a School for the Mentally Retarded in Bandung. PI [Internet]. 13Jun.2017 [cited 27Apr.2024];18(5-6):141-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1478
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Received 2017-06-05
Accepted 2017-06-05
Published 2017-06-13
Accepted 2017-06-05
Published 2017-06-13
