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Background Urinary tract infection (UTI) is common in children
and, if incorrectly handled, may cause long-term complications,
such as renal failure. The best test to diagnose UTIs is urine
culture. However, urine culture is time-consuming, taking 3 - 5
days. Therefore, there is a need for faster, alternative methods.
Urinalysis is a common diagnostic test to establish the diagnosis
Objective To determine the sensitivity and
specificity of urine leukocytes, nitrite and leukocyte esterase for
Methods We performed diagnostic tests at Dr. Sardjito Hospital,
Yogyakarta. We examined the presence of leukocytes in urine by microscopy,urinary nitrite and leukocyte esterase by dipstick test, while comparing to urine culture as the gold standard.
Results Two hundred children were included in our study. By
parallel test analysis, we found the sensitivity, specificity, positive
predictive value and negative predictive value of using all 3 tests
in combination were 95%, 59%, 74% and 89%, respectively
Conclusion Test for urine leukocytes, nitrite and leukocyte
esterase have high sensitivity but low specificity for diagnosing
UTIs. Therefore, negative results in these 3 tests do not rule
out the possibility of UTI in children. [Paediatr Indones.
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