Confusions and dilemma around hepatic dysfunction associated falciparum malaria: A case report and brief review of the literature
Abstract
Malaria remains a big burden in East Indonesia. Severe malaria assaults children in endemic area and leads to
enormous morbidities and mortalities.
According to the World Health Organization's criteria,
recognition of one or more of the following clinical
features should raise the suspicion of severe malaria
i.e, cerebral malaria (unrousable coma), severe anemia
(hemoglobin <5 g/dl), renal failure (creatinine serum
> 3 mg/dl), pulmonary edema or adult respiratory distress
syndrome (ARDS), hypoglycemia (glucose < 40 mg/dl),
circulatory collapse or shock, disseminated intravascular
coagulation (DIC), repeated generalized convulsions,
acidosis (pH < 7 .25), macroscopic hemoglobinuria,
hyperparasitaemia ( > 5% of the erythrocytes infested by
parasites), or jaundice (bilirubin> 3 mg/dl).l-3
Jaundice in malaria due to hepatic dysfunction is
a classical case, nevertheless, there are some confusions
and dilemmas in managing it.1 We report a case with
jaundice due to hepatic dysfunction and hemolysis
associated falciparum malaria that we treated in
General Hospital of Fakfak, West Papua, and provide
a brief literature review on the matter.
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Accepted 2016-09-10
Published 2009-08-31
