Main Article Content
Background Congenital malformations are a global and continual
issue, contributing to neonatal mortality. The incidence and
prevalence, as well as distribution of congenital malformations
vary among countries.
Objective To determine the 'prevalence, distribution, and trends
in congenital malformations which are important to develop plans
to cope Mth the problem.
Methods We reviewed all cases of congenital malformations
admitted to the Neonatal Unit, Department of Child Health,
Arifin Ahmad Hospital from 2008 to 2010. Data were collected
from medical records. Diagnoses of congenital malformations
were established by history-taking, physical examination,
and specific laboratory tests. Trends in the distribution of
congenital malformation types, as well as clinical outcomes were
Results During the study period there were 2,317 infants admit-
ted to the Neonatal Unit, 724 in 2008, 772 in 2009, and 821 in
2010. Most patients were referred by other hospitals, at the age
of 0-3 days. Most patients had normal birth weight and were de-
livered vaginally. Of the 2,317 infants, 302 were diagnosed with
congenital malformations; the most common congenital malfor-
mations were of the digestive tract. The distribution of anomaly
types was relatively constant over time, but the proportion of
patients Mth congenital malformations discharged alive increased
in the latter two years of the 3-year period studied.
Conclusion Most infants in our study had congenital malforma-
tions involving the gastrointestinal tract. Distribution trends
were constant over time. Further efforts should be made to better
manage future cases. [Paediatr lndones. 2012;52:284,8].
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malformations: etiologic factors and their role in prevention
( first of two parts). N Engl J Med. 1983;308A24-31.
2. Stringer MD, Sugarman I, Smyth AG. Congenital defects and
surgical problems. In: Rennie JM, editor. Roberton's textbook
of neonatology. 4th ed. London: Churchill livingstone; 2005.
3. Lub FI. Neonatal surgery. In: Oh W, editor. Evidence-based
handbook of neonatology. New Jersey : World Scientific; 2011.
4. International Statistical Classification of D iseases and
Related Health Problems 10th Revision (ICDlO) Version for
2007 [cited October 2011]. Available from: http://apps.who.
int/classificationsl appslicd/icd 1 Oonline2 0071
5. La\Vll JE, Cousens S, Zupan J, Lancet Neonatal Survival
Steering Team. 4 million neonatal deaths: when? where?
why? Lancet. 2005;365:891-900.
6. Perinatal Mortality Study Group. Perinatal mortality rate
- hospital based study during 1998-2001 at H acettepe
University. J Perinat Med. 2003;31A35AO.
7. Wiziy anti E. Angka kejadian congenital malformations di
RSUP DR. Sardjito Yogyakarw whun 2004 - 2007 [cited
2011 October 17]. Available from: http://etd.eprints.ums.
8. Tomatir AG, Demirhan H, Sorkun HC, Kobal A, Ozerdem
F, Cilengir N. Major congenital anomalies: a five-year
retrospective regional study in Turkey. Genet Mol Res.
9. Oztarhan K, Gedikbasi A, Yildirim D, Arslan 0, Adal
E, Kavuncuoglu S, et al. Prevalence and distribution of
congenital abnormalities in Turke y : differences between
the prenatal and postnatal periods. Congenit Anom.
10. Jehangir W, Ali F, Jahangir T, Masood MS. Prevalence of
gross congenital malformations at birth in the neonates in a
tertiary care hospital. APMC. 2009;3:47-50.
11. Abdi-Rad I, Khoshkalam M, F arrokh-Islamlou HR. T he
prevalence at birth of overt congenital anomalies in Urmia, Northwestern Iran. Arch Iran Med. 2008;11:148-51.
12. Taksande A, Vilhekar K, Chaturvedi P, Jain M. Congenital
malformations at birth in Central India: a rural medical college
hospital-based data. Indian J Hum Genet. 2010; 16: 159-63.
13. Singh A, Gupta RK. Pattern of congenital anomalies
in newborn: a hospital based prospective study. JK Sci. 2009;1 U4·6.
14. Swain S, Agrawal A, Bhatia BD. Congenital malformations
at birth. Indian Pediatr. 1994;3 U 187 ·91.
15. Jackson FL. Human genetic variation and health: new
assessment approaches based on ethnogenetic layering. Br
Med Bull. 2004;69,215·35.