Proteinuria and malaria parasite counts in children

  • Mahrani Lubis Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital
  • Rusdidjas Rusdidjas Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital
  • Rafita Ramayati Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital
  • Oke Rina Ramayani Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital
  • Rosmayanti S Siregar Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital
  • Supriatmo Supriatmo Department of Child Health, University of North Sumatera Medical School, H. Adam Malik Hospital
Keywords: proteinuria, malaria, Plasmodium f alciparum, kidney involvement

Abstract

Background Malaria-induced proteinuria has been observed in
severe cases of malaria. Few studies have been done to assess for
an association between proteinuria and malaria parasite counts
before the disease becomes severe.
Objective To investigate a possible association between proteinuria
and malaria parasite counts in children .
Methods A cross-sectional study was conducted on school-aged
children in Panyabungan, Mandailing Natal, between September
to November 2010. Malaria was diagnosed by microscopic
examination of peripheral blood smears. Children with malaria
underwent proteinuria t ests by urine dipstick method. An
association between proteinuria and malaria parasite counts was
analyzed using linear regression test.
Results Of 181 participants with Plasmodium fak:iparum malaria,
53.6% were female and had a mean age of 7.8 years. Subjects'
nutritional status were as follows: 50.8% normoweight, 28.2%
mild malnutrition, 3 .3% moderate malnutrition, and 17. 7% severe
malnutrition. Clinical manifestations showed 36.5% suffered from
subfebrile temperatures and 29.8% had pallor. Proteinuria occurred
in 45.9% participants and there was a weak association between
proteinuria and malaria parasite counts (raa .261, Paa .0001).
Conclusion There is a weak association between proteinuria and
malaria parasite counts in children.

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Published
2013-12-30
How to Cite
1.
Lubis M, Rusdidjas R, Ramayati R, Ramayani O, Siregar R, Supriatmo S. Proteinuria and malaria parasite counts in children. PI [Internet]. 30Dec.2013 [cited 29Mar.2024];53(6):295-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/310
Received 2016-08-21
Accepted 2016-08-21
Published 2013-12-30