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months. History of atopy in parents, non-exclusive breastfeeding,
exposure to cigarette smoke, and infants living in crowded areas
may be risk factors for bronchiolitis. Gestational of age at birth is
also influences the mortality oflower respiratory tract infection.
Objective To evaluate the following conditions as possible
risk factors for bronchiolitis: history of atopy, non-exclusive
breastfeeding, preterm infants, exposure to cigarette smoke, and
2:: 6 persons residing in the home.
Methods A sex-matched case-control study was conducted
by collecting data from medical records at Sanglah Hospital,
Denpasar. The case group subjects met the diagnostic criteria
for bronchiolitis and were aged 1-24 months. The control group
included patients with diagnoses unrelated to the respiratory
system. Data was analyzed using bivariate (Mc.N emar) and
multivariate methods (logistic regression) with 95% confidence
intervals and statistical significance value of P <0 .05.
Results There were 96 subjects in our study, consisted of 48
subjects in the case group and 48 in the control group. The
case and control groups were similar in baseline characteristics.
The presence of history of atopy (OR 34.7; 95%CI 3 to 367,
P=0.003), non-exclusive breastfeeding (OR 4.3; 95%CI 1.4 to
13, P=0.010), exposure to cigarette smoke (OR 3; 95%CI 1 to
9.2, P=0.047), and 2:: 6 persons living in the home (OR 7.9;
95%CI 2.6 to 24, P<0.0001) were found to be significant risk
factors for bronchiolitis, while the preterm infants seem not
significant as a risk factor of bronchiolitis (OR3; 95%CI 0.31 to
Conclusion History of atopy, non-exclusive breastfeeding,
exposure to cigarette smoke, and 2:: 6 persons living in the home
are found to be risk factors, while preterm infants seem not a risk
factor for bronchiolitis.
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