Isosexual precocity in girls

  • M. Suttan Assin Clinic for Pediatric and Adolescent Endocrinology, Department of Child Health, Universitas Indonesia Medical School, Jakarta
Keywords: isosexual precocity; puberty; true sexual; pseudosexual; hypothalamic-pituitary axis; gonads; adrenal glands

Abstract

Puberty is considered precocious when the onset takes place prior to eight years of age. lsosexual precocious puberty indicates that sexual development has occurred appropriate io the individual's phenotype. This can be a) true sexual or b) pseudosexual. In true sexual precocity there is a premature activation of hypothalamic-pituitary axis, while pseudosexual precocity is due to disease of the gonads or adrenal glands or, rarely, other hormone producing tissues. Incomplete sexual development can be ''premature thelarche'' or "premature pubarche". We have encountered 13 cases of precocious puberty in girls in 10 years time (1971 - 1980). Eight of them were idiopathic. Diagnostic procedures, medical treatment and psychosocial handling are discussed in this paper.

References

1. GLENN et al. quoted by HAHN, H.B.; HAYLES, .A.B.;ALBERT, A.: ln Medroxyprogesteron and Constitutional Precocious Puberty, Mayo Clin. Proc. 39:182-190 (1964).
2. HAHN, H.B. ; HAYLES, A.B.; ALBERT, A.: Medroxyprogesteron and Constitutional Precocious Puberty, Mayo Clin . Proc. 39 : 182" 190 (1964).
3. HUBBLE, D. : Paediatric Endocrinology (Blackwelb Scient. Pub!., Oxford and Edinburgh 1969).
4. HUNG, W., AUGUST, G.P., GLASGOW A.M.; Pediatric Endocrinology. (Topan: Singapore (1978).
5. JOB, J.L.; PIERSON, M.: Pediatric Endocrinology, (John Wiley & Sons, New York 1981).
6. JOLLY J-1. ; Sexual Precocity. Sprlngfield Thomas 1955; quoted by Wilkins, L., in The Diagnosis and management of Endocrine Disorders and Adolescence. (Charles C. Thomas PubL, Springfield III. 1965).
7. KAULI, R.; PERTZELAN, A.; PRAGERLEWIN, R.; RUNEB AUM, M.; LARON, Z. : Cyproterone acetate in. treatment of precocious Puberty, Archs. Dis. Childh. 51 : 202 (1976) .
8. KRYSTON, L.J. : Endocrine Disorders (Med. Exam Pub!.. New Work (1981).
9. KUPFERMAN, H.S., EPSTEIN, J.A. : Medroxyprogesterone acetate in the treatment of constitutional sexual precocity. J . Clin. Endocr. 22: 456, 1962.
10. DDO W.O.; LEA H, R.B.; TOK Y M ,I.; PAULSEN, A.; RO , W.R.: Effect of hog Pituitary follicle stimulating
hormone in women : antihormone formation and inhibition of ovarian function. J. Clin. Endocr., 16: 433, 1956.
11. NEUMANN, F.; HAMADA, H. (1965) quoted by KAULI, R. et al.: Cyproterone acetate in treatment of precocious puberty, Archs. Dis. Childh. 51: 202 (1978).
12. SECKEL, H.P.G.; Med. Clin. N. Amer., p. 183,1946; quoted by WILKINS, L., in The Diagnosis and Treatment of Endocrine Disorders and Adolescence. (Charles C. Thomas Publi., Springfield, III. 1965).
13. THAMDRUP, E.; Precocious Sexua1 Development, Springfield, Thomas, t961; quoted by Whlkins, L ., in The Diagnosis and Treatment of Endocrine Disorders and Adolescence (Charles C. Thomas Publ., Springfield, III. 1965).
14. WILKINS, L.: The Diagnosis and Treatment of Endocrine Disorders of Child hood and Adolescence (Charles C. Thomas Publ., Springfield, III. 1965).
Published
2018-08-03
How to Cite
1.
Assin M. Isosexual precocity in girls. PI [Internet]. 3Aug.2018 [cited 20Apr.2024];24(1-2):17-2. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1908
Section
Developmental Behavioral & Community Pediatrics
Received 2018-08-03
Published 2018-08-03