Clinical features and specific lgE in babies and children with cow's milk allergy

  • Syawitri P. Siregar Department of Child Health, Medical School, University of Indonesia, Jakarta
  • Ida Mardiati Department of Child Health, Medical School, University of Indonesia, Jakarta
  • Arwin P. Akib Department of Child Health, Medical School, University of Indonesia, Jakarta
Keywords: specific IgE, cow's milk allergy, cough, diarrhea, atopy

Abstract

A discriptive prospective study was done on babies & children not older
than 3 years of age who came to Pediatric Allergy & Immunology Clinic, Medical School, University of Indonesia - Cipto Mangunkusumo Hospital, Jakarta, during the period of April I 996-March I 997. Screening test included interview, physical examination elimination and open provocation. The aim of the study was to determine clinical features and specific lgE of babies and children with cow's milk allergy (CMA). Among 541 patients, 18 were diagnosed as CMA. The most common clinical symptoms was cronic and recurrent cough (CFC), while only 5 patients were suffering from diarrhea. Specific IgE examination gave positive results on 7 patients, skin tests were positive in 11 patients, and increased total lgE count were found in 13 patients. All CMA patients had family history of atopies.

References

1. WalkerWA. Adverse reactions to foods in infancy and childhood. J Pediatr 1992; 121:4-6.
2. Schwartz HR. IgE mediated allergic reactions to cow's milk. Immunol Clin North Am 1991; 11:717-41.
3. Gerrad JW, Mackenzie JWA, Goluboff N, et al. Cow's allergy: Prevalence and manifestations in unselected series of newboms. Acta Paediatr Scand 1973; 234:1-21.
4. Siregar SP. Alergi susu sapi pada bayi dan anak. Presented in Malam Klinik IDAI Jaya, Jakarta, 5 February 1992.
5. Owen G. Infant protein allergy: Its origins and management Guest Lecture, Department of Child Health, Medical School, University of Indonesia, Jakarta, October 20, 1991.
6. Jakobsson I, Lindberg T, Benediktsson B, et al. Diitary bovine beta lactoglobulin is transferred to human milk. Acta Paediatr Scand 1985; 74:342-5.
7. Axelsson I, Jakobsson I, Lindberg T, et al. Bovine beta lactoglobulin in the human milk. Acta Paediatr Scand 1986; 75:702-7.
8. Anderson JA. Adverse reactions to fOod. In: Bierman CW, Pearlman OS, editors. Alergic diseases from infancy to adulthood; edisi ke-2. Philadelphia: Saunders, 1988; 130-40.
9. Marks DR, Marks LM. Food Allergy. Manifestations, evaluation, and management. Postgrad Med 1993; 93:191-6.
10. Goldman AS, Anderson DW Jr, Sellers WA, et al. Milk allergy. I. Oral challenge with milk and isolated milk proteins in allergic children. Pediatrics 1963; 32:425-43.
11. Gryboski JD. Gastrointestinal aspects of cow's milk protein intolerance and allergy. J Immunol Allergy Clin North Am 1991; 11:773-97.
12. Bishop JA, Rafei AE, Peters SM, Harris N. Comparative studies of specific IgG4 and IgE antibody in patient with food allergy. Food allergy. New York: Raven Press, 1988; 51-61.
13. Horword W, Ferguson DM, Shannon FR. Social and familial factors in the development of early childhood asthma. Pediatr 1985; 75:859-68.
14. Savilahti E, Kuitunen M. Alergenicity of cow's milk proteins. Dalam: Esteban MM, penyunting. Adverse reactions to foods in infancy and childhood. J Pediatr 1992; 121:12-20.
Published
1999-04-30
How to Cite
1.
Siregar S, Mardiati I, Akib A. Clinical features and specific lgE in babies and children with cow’s milk allergy. PI [Internet]. 30Apr.1999 [cited 28Mar.2024];39(3-4):83-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1683
Section
Pediatric Allergy Immunology
Received 2017-11-16
Published 1999-04-30