The Correlation Between PPD and BCG Vaccination

  • T. Kustiman Department of Child Health, Medical School University of Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung and PT Perkebunan XIII, Bandung.
  • H. Garna Department of Child Health, Medical School University of Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung and PT Perkebunan XIII, Bandung.
  • J. Abdulkadir Department of Child Health, Medical School University of Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung and PT Perkebunan XIII, Bandung.
  • E. Nurhadi Department of Child Health, Medical School University of Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung and PT Perkebunan XIII, Bandung.
DOI: https://doi.org/10.14238/pi19.1-2.1979.1-10
Keywords: PPD, BCG vaccination

Abstract

During the period of October 1975-January 1976 a study on the correlation between induration size of BCG vaccination and Mantoux test using 5 TU PPD-S has been undertaken on 1.100 non-BCG vaccinated children. Good correlation between induration, size of BCG vaccination and Mantoux test performed simultaneously were observed, particularly on the third day of examination, with the correlation equation of y=4.97 + 0.69X, and a coefficient of correlation = 0.99. Significant differences on the mean size of BCG induration on each Mantoux test group were also observed. The mean size of BCG induration in subjects showing Mantoux test of less than 5mm., 5-9mm., and 10mm. and over were 6.07mm., 12.20mm., and 16.69mm. respectively, while the standard deviation were 2.71mm., 3.65mm., and 4.31mm. respectively. It seems that BCG indication of 8mm. (3rd day) could be taken as an indication for further diagnostic studies in the early case finding of tuberculosis in children, especially in rural areas. However, further study on the correlation of BCG induration and the incidence of tuberculosis is still required.

References

COLLINS, T.F.B., S. Afr. Med. J. 39 : 847 (1958). Cited by Heaf.

HARTSTON, W. (1967) in personal communication with Heaf (1968).

HEAF, F. and RUSKY, N.L. : Recent advance in respiratory tuberculosis. Vlth Ed., pp. 23 - 66 (Churchill, London 1968).

HORWITZ, O. and BUNCH-CHRISTENSEN, K. : Correlation between tuberculin sensitivity after 2 monhs and 5 years among BCG vaccinated subjects. Bull. WHO 47 : 1, 49 — 58 (1972).

ILJAS Dt. BATOEAH : Perbandingan antara PPD clan BCG test. Berita Tuberculosa Indonesiensis, IX : 1, 2, 3, 4 (1962).

KENDIG, F.L. : Pulmonary disorders. Vol. I, pp. 642 — 690 (Saunders, Philadelphia/London/Toronto 1972).

PAGEL, W.; SIMMONDS, P.A.H.; Mc.DONALD, N. and NASSAU, E. : Pulmonary tuberculosis. Fourth Ed., pp. 485-487 (Oxford University Press, New York/Toronto 1964).

SULA (1962) in personal communication with Iljas Dt. Batoeah (1962).

SUTARJO, J. and IBRAHIM, I. : Di-BCG vaccination in Primary School children with various doses of freeze dried BCG vaccine (first communication). Bull. Bio Farma VIII : 1, 43 — 69 (1971).

SUTARJO, J. and IBRAHIM, I.: Direct BCG vaccination in young infants with various doses of freeze dried BCG vaccine (final communication). Bull. Bio Farma 10 : 16 — 32 (1973).

WATTS, T. : A pilot study in case finding and control of tuberculosis in Uganda by giving BCG to Primary School children and using accelerates reaction as index cases. Environm. Child Health 20 : 71 — 73 (1974).
Published
2017-06-16
How to Cite
1.
Kustiman T, Garna H, Abdulkadir J, Nurhadi E. The Correlation Between PPD and BCG Vaccination. PI [Internet]. 16Jun.2017 [cited 20Apr.2024];19(1-2):1-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1523
Issue
Vol 19 No 1-2 (1979): January - February 1979
Section
Articles

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Received 2017-06-14
Accepted 2017-06-14
Published 2017-06-16