Lactose intolerance among healthy adults

  • Achmad Surjono Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java
  • Teluk Sebodo Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java
  • Jati Sunarto Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java
  • Moenginah P. A. Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java
DOI: https://doi.org/10.14238/pi13.2.1973.49-54
Keywords: lactose intolerance, lactose, lactase, hydrolyzed, enzim

Abstract

Lactose occurring naturally only in milk, must be hydrolyzed into glucose and galactose by small-intestinal enzyme lactase in order to be
utilized. The production and presence of lactase is in the brush-border
of the intestinal epithelial cells and its activity takes place within those cells (Johnson, 1967; Levine and Haft, 1970). The lactase activity is ditributed uniformly throughout the small intestines, except in the duodenum and distal ileum where low levels are found (Auricchio, et al.,1965).

 

Author Biography

Moenginah P. A., Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta, Central Java

References

1. AURICCHIO. S .. RUBINO. A . LANDOLT, M., SEMENZA, G., PRODER, R.: Isolated intestinal lactase deficiency in the adult. Lancet ii : 324 (1963).
2. AURICCHIO. S .• RUBINO. A . MURSET, G.' Intestinal glycosidase activities In human embryo, fetus 811d newborn. PediatJ'ics 35: 944 (1965).
3. BAYLESS. T.M_ and ROSENSWEIG. N.S.: A racial difference in incidence of lactase deficiency. J amer. med. Ass. 197 :968 (1966). Topics in clinical medicine : Incidence and implications of llactase dieficiency in white Negro populations. John Hopkins med J. 121:54 (1967).
4· BAYLESS. T.M. and CHRISTOPHER, N.L.: Disaccharidase dificiency. Amer. J. Clin. Nutrlt. 22 : 181 (1969).
5. BAYLESS, T.M., PAIGE, D.M., FERRY, G.D. : Lactose intolerance and milk drinking habits. Gastroenterollogy 60 : 605 (1971).
6. BOWIE, M.D., BRINKMAN, G.L., JANSEN, J.D.L. : Diarrhoea in protein-calorie malnutrition. Lancet ii; 550 (1963).
7. CHUNG, M.H. and McGILL, D·B. : Lactase deficiency in Orientals. Gastroenterology 54: 225 (1968).
8. COOK, G.C. and KAJUBI, S·K. : Tribal incidence of lactase deficiency in Uganda. Lancet i : 725 (1966).
9. DANOVITCH, S.H. : The syndrome ot lactase deficiency. Gen. Pract. 33 : 117 (1966).
10. FERGUSON, A. and MAWELL, J.D. : Generic etiology of lactose intolerance. Lancet i : 188 (1967).
11. HUANG, S.S. and BAYLESS, T.M. : Milk and lactose intolerance in healthy Orientals. Science 160 : 88 (1968).
12. JAMES, W,P.T. : Sugar absortion and intestinall motility in children when malnourished and after tre 39: 305 (1970).
13. JOHNSON, C.F. : Disaccharidase, localization in Hamster intestine brushborder. Science 155: 1670 (1967).
14. KERN, F. and STRUTHERS, J.E. Lactase deficiency and lactose intolerance in adults, J. amer med, Ass. 195 : 927 (1966).
15. KRETCHMER, N., RANSOME·KUTI,
0., HURWITZ, R, DUNGY, C. and Alaraja, W. : Intestinal absorption of lactose in Nigerian ethnic groups. Lancet ii: 392 (1811).
16. LEVINE, R and HAFT, D.E. : Carbohydat e homeostasis. New Engl. J. Med. 283: 175 (1970).
17. LITTMAN, A. : Isolated lactate deficiency in the adult. J. amer med, Ass. 195: 954 (1966).
18. LUYKEN, R., LUYKEN-KONlNG, F. W.M. anld IMMlKHUIZEN, T.: Lactose intolerance in Surinam. Trap. geogr. Med. 23: 54 (1971).
19. McDONAGH, T.J.: Lactose intolerance in non-Caucasians. Med. BuR. 30 : 277 (1970).
20. McMICHAEL, H.B., WEBB, J. and DAWSON, A.M.: Lactase deficiency In adults. Lancet I : 717 (1965).
21. POLEY, J.R. : Causes of chronic diarrhea in infants and chilldren. Pract. Pediat. 48 : 143 (1970).
22. PRINSLOO, J.G., WITTMANN, W., PRETORIUS, P.J. KRUGER, H. and FELLINGHAM. S.A. : Effect of different sugars on diarrhea ot acute kwashiorkor. Arch. Dis. Childh. 44: 593 (1969).
23. SUHARJONO, SUNOTO, ASWITHA BUDIARSO adn SUTEDJO: Lactose malabsotion in "healthy" Indonesian Pre-School age children. Paediatr Indon. 11: 251-254 (1971).
24. SUNOTO, SUHARJONO, CYSCA M. LEMBONG, ASWITHA BUDIARSO and SAMSUDIN: Lactose loading test on Protein-Calorie Malnutrition. Paediat. Indon. 13: 43 (1973).
25. SURJONO, A.. MOENGINAH. P.A., TELUK SUBODO and JATI SUNARTO: Intole'ansi terhadap air susu sapi (lactose) pada mahasiswa kedokteran U.G.M. Berkala I. Kedokt. Gama 1971.
26. SURJONO, A., SURJANTORO, TONNY SADJIMIN, ISM AN GO EN: Lactose tolerance test on Indonesian newborn infants. Paediat Indon. 13: 11-16 (1973).
27. SUTEDJO: Cow's milk (lactose?) intolerance among Indonesian doctors of the Dr. Tjlpto Mnngunkusumo General Hospital. Jakarta. Pediat. Indon. 11: 43 (1971).
28. TRONCALE, F.J .. KEUSCH, G.T., MILLER, R.H. OLSON. RA. and BUCHANAN, R.D. : Normal absorption in subjects with non-specific jejunal abnormalitie. Br.ll mcd. J. II: 678 (1967).
29. VARAVITHYA, W. ; personal communication (1971).
30. WELESH, J.D., SHAW, R.W. and WALKER, A.' Isolated lactose deficiency producing post-gastrectomy milk intolerance. Ann. Intern. Med. 64; 1252 (1966).
Published
1973-02-28
How to Cite
1.
Surjono A, Sebodo T, Sunarto J, A. M. Lactose intolerance among healthy adults. PI [Internet]. 28Feb.1973 [cited 14Nov.2024];13(2):49-4. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1321
Issue
Vol 13 No 2 (1973): February 1973
Section
Articles

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Received 2017-03-23
Accepted 2017-03-23
Published 1973-02-28