Cognitive outcome in late preterm babies

  • Ayu Setyorini Department of Child Health, Medical School, Udayana University, Sanglah Hospital
  • Soetjiningsih Soetjiningsih Department of Child Health, Medical School, Udayana University, Sanglah Hospital
  • Ekawaty L. Haksari Department of Child Health, Medical School, Udayana University, Sanglah Hospital
Keywords: cognitive outcome, late preterm babies, Mullen Scale of Early Learning

Abstract

Background Late preterm babies are at risk for delayed cognitive outcome, but little attention has been paid on this issue. There has been a general assumption that this group of babies will have the same development as full-term babies.
Objective To compare the cognitive development between late preterm babies and full-term babies.
Methods A prospective cohort study was conducted at the Department of Child Health Medical School of Udayana University/Sanglah Hospital. Babies with 34 to 42 weeks of gestational age who were born in Sanglah Hospital between November 1st 2007 and December 31st 2008, were recruited to the study. Cognitive development of each baby was measured by Mullen Scale’s of Early Learning twice, at 7 days and 3 months of age. We used corrected age for late preterm babies and chronological age for fullterm babies.
Results The incidence of under-average development for late preterm babies at three months corrected age was 47.8% compared to 4.1% among fullterm babies (P < 0.0001). The relative risk for under-average development among late preterm babies was 11.8 (95%CI 9.95 to 13.75). Multivariate analysis revealed late preterm influenced cognitive significantly with OR 17.01 (95%CI 1.15 to 32.87).
Conclusions Cognitive outcome of late preterm babies was delayed compared to full-term babies.

References

1. Engle WA, Tomashek KM, Wallman C. “Late-preterm” infants: a population at risk. Pediatr. 2007;120:1390-401.
2. Aylward GP. Cognitive function in preterm infants, no simple answers. JAMA. 2005;289:752-3.
3. Colvin M, McGuire W, Fowlie PW. Neurodevelopmental outcomes after preterm birth. Br Med J. 2004;329:1390-3.
4. Pierrehumbert B, Nicole A, Muller-Nix C, Forcada-Guex M, Ansermet F. Parental post-traumatic reactions after premature birth: implications for sleeping and eating problems in the infant. Arch Dis Child Fetal Neonatal Ed. 2003;88:F400-4.
5. Soetjiningsih. Tumbuh-kembang anak. In: Ranuh IGNG, editor. Tumbuh kembang anak. 2nd ed. Jakarta: EGC, 1998; p. 1-36.
6. Vohr BR., O’Shea M, Wright LL. Longitudinal multicenter follow-up of high-risk infants: why, who, when, and what to assess. Semin Perinatol. 2003;27:333-42.
7. Wolke D. Psychological development of prematurely born children. Arch Dis Child. 1998;78:567-70.
8. Takahashi S, Endo A, Minato M. Why do we help a micropreemie to live? Acta Pædiatr. 2003;92:773-5.
9. Cooke RWI. Perinatal and postnatal factors in very preterm infants and subsequent cognitive and motor abilities. Arch Dis Child Fetal Neonatal Ed. 2005;90:60-3.
10. Evans DJ, Levene MI. Evidence of selection bias in preterm survival studies: a systematic review. Arch Dis Child Fetal Neonatal Ed. 2001;84:79-84.
11. Macfarlane PI., Wood S, Bennett J. Non-viable delivery at 20-23 weeks gestation: observations and signs of life after birth. Arc Dis Child Fetal Neonatal Ed. 2003;88:F199-202.
12. McCarton CM, Wallace IF, Divon M, Vaughan HG. Cognitive and neurologic development of the premature, small for gestational age infant through age 6: comparison by birth weight and gestational age. Pediatr. 1996;98:1167-78.
13. Peterson BS, Vohr B, Staib LH., Cannistraci CJ, Dolberg A, Schneider KC. Regional brain volume abnormalities and long-term cognitive outcome in preterm infants. JAMA. 2000;284:1939-47.
14. Guinn D, Gibbs R. Infection-related preterm birth: a reviewof the evidence. NeoReviews. 2002;3:e86-95.
15. Kramer MS, Demissie K, Yang H, Platt RW, Sauvé R, Liston R. The contribution of mild to moderate preterm birth to infant mortality. JAMA. 2000;284:843-9.
16. Slattery MM., Morrison JJ. Preterm delivery. Lancet. 2002;360:1489-97.
17. Morse SB, Zheng H, Tang Y, Roth J. Early school-age outcomes of late preterm infants. Pediatr. 2009;123:e622-9.
18. Windiani IGAT. Dampak stimulasi dini terhadap perkembangan bayi berat badan lahir rendah sesuai masa kehamilan pada umur koreksi 3 bulan [thesis]. Denpasar: Fakultas Kedokteran Universitas Udayana; 2004.
19. Huddy CL, Johnson A, Hope PL. Educational and behavioural problems in babies of 32–35 weeks gestation. Arch Dis Child Fetal Neonatal Ed. 2001;85:F23-8.
20. Kalia JL, Visintainer P, Brumberg HL, Pici M, Kase J. Comparison of enrolment in interventional therapies between late-preterm. Pediatr. 2009;123:804-9.
21. Billiards SS, Pierson CR, Haynes RL, Folkerth RD, Kinney HC. Is the late preterm infant more vulnerable to gray matter injury than the term infant. Clin Perinatol. 2006;33:915-33.
22. Fallang B, Hadders-Algra M. Postural behaviour in children born preterm. Neural Plast. 2005;12:175-82.
23. Goyen T, Lui K, Woods R. Visual-motor, visual-perceptual, and fine motor outcomes in very low birth weight children at 5 years. Developmental Medicine and Child Neurology. 1998 ;40:76-81.
24. Gabbard C, Goncalves VMG, Santoa DCC. Visual-motor integration problems in low birth weight infants. J of Clinical Psychology in Medical Settings. 2001;8:199-204.
25. Yliherva A, Olsen P, Maki-Torkko E, Koiranen M, Jarvelin MRMR. Linguistic and motor abilities of low-birth weight children as assessed by parents and teachers at 8 years of age. Acta Paediatr. 2001;90:1440-9.
26. Nelson HD, Nygren P, Walker M, Panoscha R. Screening for speech and language delay in preschool children: systematic evidence review for the US preventive service task force. Pediatr. 2006;117:e298-319.
27. Hohm E, Jennen-Steinmetz C, Schmidt MH, Laucht M. Language development at ten months, predictive of language outcome and school achievement ten years later? Eur Child Adolesc Psychiatry. 2007;16:149-56.
28. Kirkegaard I, Obel C, Hedegaard M, Henriksen TB. Gestational age and birth weight in relation to school performance of 10-year-old children: a follow-up study of children born after 32 completed weeks. Pediatr. 2006;118:1600-6.
29. Gale CR, O’Callaghan FJO, Godfrey KM, Law CM, Martyn CN. Critical periods of brain growth and cognitive function in children. Brain. 2004;127:321-9.
30. Cheong JLY, Hunt RW, Anderson PJ, Howard K, Thompson DK, Wang HX. Head growth in preterm infants: correlation with magnetic resonance imaging and neurodevelopmental outcome. Pediatr. 2008;121:e1534-40.
31. Shenkin SD, Starr JM, Pattie A, Rush MA, Whalley LJ. Birth weight and cognitive function at age 11 years: the Scottish mental survey 1932. Arch Dis Child. 2001;85:189-97.
32. Moster D, Lie RT, Markestad T. Long-term medical and social consequences of preterm birth. N Engl J Med. 2008;359:262-73.
33. Whitaker AH, Feldman JF, Lorenz JM, McNicholas F, Nieto M, McCulloch D, et al. Motor and cognitive outcomes in nondisabled low-birth-weight adolescents, early determinants. Arch Pediatr Adolesc Med. 2006;160:1040-6.
34. Dina D. Kejadian dan faktor risiko penyimpangan perkembangan pada bayi berat badan lahir rendah di RSUP Sanglah Denpasar [thesis]. Denpasar: Fakultas Kedokteran Universitas Udayana; 1996.
35. Gray RF, Indurkhya A, McCormick MC. Prevalence, stability, and predictors of clinically significant behavior problems in low birth weight children at 3, 5, and 8 years of age. Pediatr. 2004;114:736-43.
36. Van Baar AL, Vermaas J, Knots E, de Kleine MJK, Soons P. Functioning at school age of moderately preterm children born at 32 to 36 weeks gestational age. Pediatr. 2009;124:251-7.
37. Petrini JR, McCormick MC, Massolo M, Green NS, Escobar GJ. Increased risk of adverse neurological development for late preterm infants. J Pediatr. 2009;154:169-76.
38. Adams-Chapman I. Neurodevelopmental outcome of the late preterm infant. Clin Perinatol. 2006;33:947-64.
39. Reuner G, Hassenpflug A, Pietz J, Philippi H. Long-term development of low-risk low birth weight preterm born infants: neurodevelopmental aspects from childhood to late adolescent. Early Hum Dev. 2009;85:409-13.
40. Smith EK, Landry SH, Swank PR. The role of early maternal responsiveness in supporting school-aged cognitive development for children who vary in birth status.
Published
2010-08-31
How to Cite
1.
Setyorini A, Soetjiningsih S, Haksari E. Cognitive outcome in late preterm babies. PI [Internet]. 31Aug.2010 [cited 22Nov.2024];50(4):239-44. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1223
Section
Articles
Received 2017-01-29
Accepted 2017-01-29
Published 2010-08-31