Comparison of metabolic syndrome criteria in obese and overweight children
Abstract
Background Metabolic syndrome (MS) is a group of disorders which occur in relation to increasing body weight. Only a few studies have reported the differences in the fulfillment of MS criteria between obese and overweight children, and none were from Indonesia.
Objective To detennine the differences in metabolic syndrome disorders between obese and overweight children.
Methods A cross-sectional study was conducted in Manado from May to August 2010. The diagnosis of MS is established by fulfilling three of five criteria: waist circumference  ≥90th percentile, blood pressure ≥ 90th  percentile, fasting blood sugar (FBS) ≥ 100 mg/dL, triglycerides  ≥110 mg/dL and high density lipoprotein (HDL) ≤40 mg/dL. Obesity was defined as body mass index (BMI) of> 3 SD and overweight as BMI of 2-3 SD. Results Results ere analyzed by x2 and t-test. Results Thirty obese and 30 overweight children aged 10-14years were examined for the disorders of MS. Twentyô€„three obese and 4 overweight children had waist circumferences  ≥90th percentile. Seventeen obese and 3 overweight children had blood pressure  ≥90th percentile. No significant differences in FBS, HDL, and triglycerides were observed between the two groups. Thirteen obese children met the MS inclusion criteria, while only 1 overweight child did so (P<0.001).
Conclusions High blood pressure (≥90th percentile) and waist circumference (≥90th  percentile) occurred were observed at higher frequency in obese children than in overweight children. The occurrence of MS in obese children was significantly higher than in overweight children.
References
2. Cruz ML, Ooran MI. T he metabolic syndrome in children and adolescents. CUff Diabetes Rep. 2004;4:53-62.
3. Nader PR, O'Brien M, Houts R, Bradley R, Belsky J, Crosnoe R, et al. Identifying risk for obesity in early childhood. Pediattics.2006;llS,e594,9.
4. Berenson OS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, Wattigney WA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults: the Bogalusa Heart Study. N Engl J Med. 1995;33S:1650-6.
5. McGill HC Jr, McMahan CA, Herderick EE, Zieske AW, Malcom OT, Tracy RE, et al. Pathobiological detenninants of atherosclerosis in youth (PDAY) research group. Obesity accelerates the progression of coronary atherosclerosis in young man. Circulation. 2002;105:2712-8.
6. McGill HC Jr, McMahan CA, Zieske A W, Tracy RE, Malcom OT, Herderick E, et al. Association of coronary heart disease risk factors with microscopic qualities of coronary
atherosclerosis in youth. Circulation. 2000;102;374-9.
7. Yoshinaga M, Tanaka S, Shimago A, Sameshima K, Nishi J, Nomura Y, et al. Metabolic syndrome in overweight and obese Japanese children. Obes Res. 2005; 13: 1135-40.
8. WHO Child growth standards: length-height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. France: WHO 2006.
9. Cizmecioglu FM, Hatun S, Kalca S. Metabolic syndrome in obese Turkish children and adolescents: comparison of two diagnostic models. Turk J Pediatr. 2008;50:359-65.
10. Cook S, Weitzman M, Auinger P, Nguyen M, Dietz WHo Prevalence of a metabolic syndrome phenotype in adolescents. Arch Pediatr Adolesc Med. 2003;157:821-7.
11. Li Y, Yang YL, Zhai F, Kok Fj, Zhao j, Piao j, et al. Prevalence of the metabolic syndrome in Chinese adolescents. Br J Nutr. 2008;99:565-70.
12. Srinivasan SR, Meyers L, Berrenson GS. Change in metabolic syndrome variables since childhood in prehypertensive and hypertensive subjects. T he Bogalusa Heart Study. Hypertension. 2006;33-39.
13. Steinberger J, Daniels SR, Eckel R, Hayman L, Lusting R, McCrindle B, et al. Progress and challenges in metabolic syndrome in children and adolescents. Circulation. 2009;119:1-20.
14. Bustos P, Saez K Glaisner A, Ulloa N, Asenjo S. Metabolic syndrome in obese adolescents. Pediatr Diab. 201O:11:55-60.
15. Adam JMF. Metabolik sindrom. Bandung: Medical School, Padjajaran University, 2006.
16. Weiss R, Dziura J, Burgert TS, Tamborlane W, Taksali S, Yeckel C, et al. Obesity and the metabolic syndrome in children and adolescents. N Engl j Med. 2004;350:2362-
74.
17. De Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai N. Prevalence of the metabolic syndrome in American adolescents: findings from the third national health and nutrition examination survey. Circulation. 2004; 110:2494-7.
18. Esmaillzadeh A, Mirmiran P, Etemandi A, Azizi F. High prevalence of the metabolic syndrome in Iranian Adolescents. Obesity. 2006;3:377-82.
19. American Academy of Pediatrics Committee on Nutrition. Prevention of pediatric overweight and obesity. Pediatrics. 2003;112:424-7.
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Accepted 2016-11-23
Published 2010-10-30