Screening urinalysis for proteinuria in school children

  • Partini P. Trihono Departments of Child Health, University of Indonesia Medical School, Jakarta
  • Ina S. Timan Departments of Clinical Pathology, University of Indonesia Medical School, Jakarta
  • Supriyadi Bektiwibowo Departments of Child Health, University of Indonesia Medical School, Jakarta
  • Diana Aulia Departments of Clinical Pathology, University of Indonesia Medical School, Jakarta
  • Lukman Edwar Departments of Community Health Program, University of Indonesia Medical School, Jakarta
Keywords: asymptomatic proteinuria, urinary tract infection, screening

Abstract

Although asymptomatic proteinuria in children is uncommon, long-term follow-up of children who have persistent proteinuria reveals that they face risks to have significant glomerular changes followed by decreasing kidney function. Since 1970’s urine screening program for asymptomatic hematuria and proteinuria in schoolchildren has been conducted regularly in some countries. So far such program has never been implemented in Jakarta. As a part of The Community Health Program of the Medical School, University of Indonesia, this epidemiologic study aimed especially to look at the urine abnormalities among schoolchildren. The target population was children in grades III, IV and V of 4 elementary schools in Eastern Jakarta. Four hundred and forty nine children (217 boys and 232 girls) were enrolled in this study, held during school time in August 1999. Their mean age was 9.35 (SD 1.2) years. Data collected were history of illness, physical examination, and complete urinalysis using a dipstick method. Proteinuria was found in 30 (6.8%) children, which in repeated urinalyses were determined as orthostatic in 2 (0.4%), transient in 20 (4.5%), and persistent proteinuria in 6 (1.4%) children. Three out of 6 children with persistent proteinuria also had hematuria. One child with persistent proteinuria was considered as having urinary tract infection. We conclude that the incidence of asymptomatic proteinuria in schoolchildren is not high, but because of significant risks that they face, a long-term follow up of them is indicated.

References

1. Makker SP. Proteinuria. In: Kher KK, Makker SP, editors. Clinical pediatric nephrology. Toronto: Mc Graw Hill; Toronto. p. 117-36.
2. Dodge WF, West EF, Smith EH, Bunce H. Proteinuria and hematuria in schoolchildren: epidemiology and early natural history. J Pediatr 1976; 88:327-47.
3. Vehaskari VM, Rapola J. Isolated proteinuria: analysis of a school age population. J Pediatr 1982; 101:661-8.
4. Yoshikawa N, Kitagawa K, Ohta K, Tanaka R, Nakamura H. Asymptomatic constant isolated proteinuria in children. J Pediatr 1991; 119:375-9.
5. Kitagawa T. Screening for asymptomatic hematuria and proteinuria in schoolchildren. Relationship between clinical laboratory findings and glomerular pathology or prognosis.
Acta Paediatr Jpn 1985; 27:366-73.
6. Robson AM, Vehaskari VM. Proteinuria. In Postlethwaite RJ, editor. Clinical paediatric nephrology. 2nd ed. Oxford: Butterworth Heinemann; 1994. p. 15-31.
7. Yoshikawa N, Ito H, Akamatsu R. Focal segmental glomerulosclerosis with and without nephrotic syndrome in children. J Pediatr 1986; 109:65-70.
8. Yoshikawa N, Iijima K, Machara K. Mesangial changes in IgA nephropathy in children. Kidney Int 1987; 32:585-9.
9. Asami T, Hayakawa H, Ohkawa K, Uchiyama M. Hypercholesterolemia and glomerular diseases in urinary screening of schoolchildren. Pediatr Nephrol 1999; 13:125-8.
10. Hisano S, Kwano M, Hatae K, Kaku Y, Yamane I, Kohji U, et al. Asymptomatic isolated microhematuria: natural history of 136 children. Pediatr Nephrol 1991; 5:578-81.
Published
2001-10-30
How to Cite
1.
Trihono P, Timan I, Bektiwibowo S, Aulia D, Edwar L. Screening urinalysis for proteinuria in school children. PI [Internet]. 30Oct.2001 [cited 26Apr.2024];41(9-10):231-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/1057
Received 2016-11-21
Accepted 2016-11-21
Published 2001-10-30