Detecting proteinuria: A comparison of diagnostic tests

Main Article Content

Jeanida Mauliddina
Rosmayanti Siregar
Oke Rina Ramayani
Rafita Ramayati
Rusdidjas Rusdidjas

Abstract

Background Proteinuria is a condition when protein is found in urine, a common symptom in children with renal disorders. Proteinuria can also be found in nonnal children and in those with non-renal disorders. A high sensitivity test is needed to detect proteinuria. Spectrophotometry has been used as a standard to detect proteinuria, however, it is expensive and not readily available in health clinics. We tested the use of20% sulfosalicylic add to detect proteinuria, and compared it to spectrophotometry. The sulfosalicylic add test is inexpensive, rapid, and easily performed in primary community health centers.

Objective To compare 2 0 % sulfosalicylic acid test t o spectrophotometry as a diagnostic test for proteinuria.

Methods We conducted a cross-sectional study in Adam Malik Hospital from September 2009 until December 2009. Inclusion criteria were children aged 3 to 18 years who experienced kidney disease. We collected 24 hour urine specimens from 55 children by consecutive sampling. Urine specimens were tested for proteinuria by 20% sulfosalicylic acid test and spectrophotometry.

Results Sensitivity and specificity of 20% sulfosalicylic acid test compared to spectrophotometry were 88.1 % and 69.2%, respectively, with a positive predictive value and a negative predictive value of 90.2% and 64.3%, respectively.

Conclusion The sulfosalicylic acid test had low sensitivity and specificity for detecting proteinuria, but it was more practical and less expensive compared to spectrophotometry.

Article Details

How to Cite
1.
Mauliddina J, Siregar R, Ramayani O, Ramayati R, Rusdidjas R. Detecting proteinuria: A comparison of diagnostic tests. PI [Internet]. 28Feb.2011 [cited 19Jul.2019];51(1):17-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/941
Section
Articles
Received 2016-10-17
Accepted 2016-10-17
Published 2011-02-28

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