Phenobarbital overdose in an eleven-year-old-girl with attempted suicide
Keywords:
Phenobarbital overdose, eleven-year-old-girl, attempted suicide
Abstract
This report describes a patient with life-threat-ening phenobarbital overdose, treated successfully
with hemodialysis, using a high-flux, high-efficiency
dialyzer and high blood flow rates. The rapid fall in
phenobarbital levels and the dramatic clinical re-
sponse noted during the procedure supports this
technique as an effective therapy in such patients.
References
1. Habal R. Toxicity, barbiturate. Available from: URL: http:/
/www.emedicine.com/med/by name/toxicity-barbiturate.
htm
2. Homan CS, Ryan JG. Enhancement of elimination. In:
Viccellio P, editor. Handbook of medical toxicology. 1st
ed. Boston: Little, Brown and Company; 2000. p. 106-17.
3. Winchester JF, Kitiyakara C. Use of dialysis and
hemoperfusion in treatment of poisoning. In: Daugirdas
JT, Blake PG, Ing TS, editors. Handbook of dialysis. 3rd
ed. Philadelphia: Lippincott Williams & Wilkins; 2001.
p. 263-80.
4. Levy J. Haemodialysis and haemoperfusion for poison-
ing. In: Levy J, Morgan J, Brown E, editors. Oxford hand-
book of dialysis. 1st ed. London: Oxford University Press;
2001. p. 204-7.
5. American Academy of Child and Adolescent Psychia-
try. Practice parameter for the assessment and treatment
of children and adolescents with suicidal behavior. J Am
Acad Child Adolesc Psychiatry 2001;40(7):24-51.
6. McNamara JO. Drugs effective in therapy of the epilep-
sies. In: Hardman JG, Limbird LE, Gilman AG, editors.
Goodman & Gilman’s the pharmacological basis of thera-
peutics. 10th ed. New York: McGraw-Hill; 2001. p. 412-
9.
7. Schiebel N, Vicas I. Barbiturates. In: Delaney KA, Ling
LJ, Erickson T, Ford MD, editors. Clinical toxicology. 1st
ed. Philadelphia: WB Saunders; 2001. p. 569-73.
8. Abbruzzi G, Stork CM. Pediatric toxicologic concerns.
Emerg Med Clin North Am 2002;20(1):223-47.
9. Lindberg MC, Cunningham A, Lindberg NH. Acute phe-
nobarbital intoxication. South Med J 1992;85(8):803-7.
10. Frenia ML, Schauben JL, Wears RL. Multiple-dose acti-
vated charcoal compared to urinary alkalinization for
the enhancement of phenobarbital elimination. J Toxicol
Clin Toxicol 1996;34(2):169-75.
11. Pastan S, Bailey J. Dialysis therapy. N Engl J Med
1998;338(20):1428-37.
12. Palmer BF. Effectiveness of hemodialysis in the extracor-
poreal therapy of phenobarbital overdose. Am J Kidney
Dis 2000;36(3):640-3.
/www.emedicine.com/med/by name/toxicity-barbiturate.
htm
2. Homan CS, Ryan JG. Enhancement of elimination. In:
Viccellio P, editor. Handbook of medical toxicology. 1st
ed. Boston: Little, Brown and Company; 2000. p. 106-17.
3. Winchester JF, Kitiyakara C. Use of dialysis and
hemoperfusion in treatment of poisoning. In: Daugirdas
JT, Blake PG, Ing TS, editors. Handbook of dialysis. 3rd
ed. Philadelphia: Lippincott Williams & Wilkins; 2001.
p. 263-80.
4. Levy J. Haemodialysis and haemoperfusion for poison-
ing. In: Levy J, Morgan J, Brown E, editors. Oxford hand-
book of dialysis. 1st ed. London: Oxford University Press;
2001. p. 204-7.
5. American Academy of Child and Adolescent Psychia-
try. Practice parameter for the assessment and treatment
of children and adolescents with suicidal behavior. J Am
Acad Child Adolesc Psychiatry 2001;40(7):24-51.
6. McNamara JO. Drugs effective in therapy of the epilep-
sies. In: Hardman JG, Limbird LE, Gilman AG, editors.
Goodman & Gilman’s the pharmacological basis of thera-
peutics. 10th ed. New York: McGraw-Hill; 2001. p. 412-
9.
7. Schiebel N, Vicas I. Barbiturates. In: Delaney KA, Ling
LJ, Erickson T, Ford MD, editors. Clinical toxicology. 1st
ed. Philadelphia: WB Saunders; 2001. p. 569-73.
8. Abbruzzi G, Stork CM. Pediatric toxicologic concerns.
Emerg Med Clin North Am 2002;20(1):223-47.
9. Lindberg MC, Cunningham A, Lindberg NH. Acute phe-
nobarbital intoxication. South Med J 1992;85(8):803-7.
10. Frenia ML, Schauben JL, Wears RL. Multiple-dose acti-
vated charcoal compared to urinary alkalinization for
the enhancement of phenobarbital elimination. J Toxicol
Clin Toxicol 1996;34(2):169-75.
11. Pastan S, Bailey J. Dialysis therapy. N Engl J Med
1998;338(20):1428-37.
12. Palmer BF. Effectiveness of hemodialysis in the extracor-
poreal therapy of phenobarbital overdose. Am J Kidney
Dis 2000;36(3):640-3.
Published
2016-10-13
How to Cite
1.
Limantara V, Widia M, Suwitra K, Ardjana E. Phenobarbital overdose in an eleven-year-old-girl with attempted suicide. PI [Internet]. 13Oct.2016 [cited 23Dec.2024];45(5):223-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/844
Section
Case Report
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Received 2016-10-10
Accepted 2016-10-10
Published 2016-10-13
Accepted 2016-10-10
Published 2016-10-13
