Phenobarbital overdose in an eleven-year-old-girl with attempted suicide
Keywords:
Phenobarbital overdose, eleven-year-old-girl, attempted suicide
Abstract
This report describes a patient with life-threat-ening phenobarbital overdose, treated successfully
with hemodialysis, using a high-flux, high-efficiency
dialyzer and high blood flow rates. The rapid fall in
phenobarbital levels and the dramatic clinical re-
sponse noted during the procedure supports this
technique as an effective therapy in such patients.
References
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Emerg Med Clin North Am 2002;20(1):223-47.
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nobarbital intoxication. South Med J 1992;85(8):803-7.
10. Frenia ML, Schauben JL, Wears RL. Multiple-dose acti-
vated charcoal compared to urinary alkalinization for
the enhancement of phenobarbital elimination. J Toxicol
Clin Toxicol 1996;34(2):169-75.
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/www.emedicine.com/med/by name/toxicity-barbiturate.
htm
2. Homan CS, Ryan JG. Enhancement of elimination. In:
Viccellio P, editor. Handbook of medical toxicology. 1st
ed. Boston: Little, Brown and Company; 2000. p. 106-17.
3. Winchester JF, Kitiyakara C. Use of dialysis and
hemoperfusion in treatment of poisoning. In: Daugirdas
JT, Blake PG, Ing TS, editors. Handbook of dialysis. 3rd
ed. Philadelphia: Lippincott Williams & Wilkins; 2001.
p. 263-80.
4. Levy J. Haemodialysis and haemoperfusion for poison-
ing. In: Levy J, Morgan J, Brown E, editors. Oxford hand-
book of dialysis. 1st ed. London: Oxford University Press;
2001. p. 204-7.
5. American Academy of Child and Adolescent Psychia-
try. Practice parameter for the assessment and treatment
of children and adolescents with suicidal behavior. J Am
Acad Child Adolesc Psychiatry 2001;40(7):24-51.
6. McNamara JO. Drugs effective in therapy of the epilep-
sies. In: Hardman JG, Limbird LE, Gilman AG, editors.
Goodman & Gilman’s the pharmacological basis of thera-
peutics. 10th ed. New York: McGraw-Hill; 2001. p. 412-
9.
7. Schiebel N, Vicas I. Barbiturates. In: Delaney KA, Ling
LJ, Erickson T, Ford MD, editors. Clinical toxicology. 1st
ed. Philadelphia: WB Saunders; 2001. p. 569-73.
8. Abbruzzi G, Stork CM. Pediatric toxicologic concerns.
Emerg Med Clin North Am 2002;20(1):223-47.
9. Lindberg MC, Cunningham A, Lindberg NH. Acute phe-
nobarbital intoxication. South Med J 1992;85(8):803-7.
10. Frenia ML, Schauben JL, Wears RL. Multiple-dose acti-
vated charcoal compared to urinary alkalinization for
the enhancement of phenobarbital elimination. J Toxicol
Clin Toxicol 1996;34(2):169-75.
11. Pastan S, Bailey J. Dialysis therapy. N Engl J Med
1998;338(20):1428-37.
12. Palmer BF. Effectiveness of hemodialysis in the extracor-
poreal therapy of phenobarbital overdose. Am J Kidney
Dis 2000;36(3):640-3.
Published
2016-10-13
How to Cite
1.
Limantara V, Widia M, Suwitra K, Ardjana E. Phenobarbital overdose in an eleven-year-old-girl with attempted suicide. PI [Internet]. 13Oct.2016 [cited 22Nov.2024];45(5):223-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/844
Section
Case Report
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Received 2016-10-10
Accepted 2016-10-10
Published 2016-10-13
Accepted 2016-10-10
Published 2016-10-13
