Urinary tract infection among neonatal sepsis of late-onset in Cipto Mangunkusumo Hospital

  • Novie Amelia
  • Idham Amir
  • Partini P Trihono
Keywords: urinary tract infection, late-onset sepsis, neonate


Background Urine culture, as part of a full septic work-up for
late-onset neonatal sepsis, was not routinely done in the Neona-
tal Ward at Cipto Mangunkusumo Hospital, and as of today, the
prevalence of urinary tract infection (UTI) among neonates with
late-onset sepsis remains unknown.
Objectives To determine the prevalence and microbiological pat-
terns of UTI among late-onset neonatal sepsis in Cipto
Mangunkusumo Hospital.
Methods We conducted a cross-sectional study on all neonates
diagnosed as suspected late-onset sepsis who underwent sep-
sis evaluation between 20 October 2003 – 30 April 2004. Urine
specimens were collected by bladder catheterization for culture
and urinalysis.
Results UTI was found in 14.9% (7/47) neonates who under-
went urine culture (male: female ratio was 5:2). Six subjects
who had UTI were preterm neonates, Klebsiella pneumoniae
was found in both blood and urine cultures of 1 subject, while the
others showed different microorganisms. Forty-five out of 47
subjects, who were suspected of late-onset sepsis, had posi-
tive blood cultures. All subjects with UTI had positive bacteriuria
from Gram-stained specimen.
Conclusions The prevalence of UTI among neonates with late-
onset sepsis in Cipto Mangunkusumo Hospital was 14.9%. The
microorganisms most frequently found in urine cultures were
Pseudomonas sp., Staphylococcus epidermidis, and Klebsiella
pneumoniae. Urine culture, urinalysis, and urinary Gram-stain
should be performed as part of sepsis evaluation for late-onset
neonatal sepsis, especially in male and preterm neonates

Author Biographies

Novie Amelia
Department of Child Health, Medical School, University of
Indonesia, Jakarta, Indonesia.
Idham Amir
Department of Child Health, Medical School, University of
Indonesia, Jakarta, Indonesia.
Partini P Trihono
Department of Child Health, Medical School, University of
Indonesia, Jakarta, Indonesia.


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How to Cite
Amelia N, Amir I, Trihono P. Urinary tract infection among neonatal sepsis of late-onset in Cipto Mangunkusumo Hospital. PI [Internet]. 13Oct.2016 [cited 20Jan.2022];45(5):217-2. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/843
Received 2016-10-10
Accepted 2016-10-10
Published 2016-10-13