Macronutrient malabsorption in acute diarrhea: Prevalence and affecting factors

  • Lilis D. Hendrawati
  • Agus Firmansyah
  • Darlan Darwis
Keywords: Acute diarrhea, malabsorption syndrome, stool analysis

Abstract

Introduction Diarrhea remains a major problem for community
health in Indonesia. More than 25% of children with severe diar-
rhea suffer from malabsorption syndrome.
Objectives This study aimed to determine the age range of chil-
dren with acute diarrhea, the prevalence of macronutrient malab-
sorption, and the relationship between age and bacterial infec-
tion in macronutrient malabsorption.
Methods This was a cross-sectional study, subjects were chil-
dren aged 0-59 months with acute diarrhea whose stools were
obtained and examined in the laboratory of Gastrohepatology
Division, Department of Child Health, Cipto Mangunkusumo Hospi-
tal, Jakarta from January 2002 to December 2003.
Results Children with acute diarrhea were mostly in the age
range of 0-11 months (61%). The prevalence of lactose malab-
sorption was 11%, carbohydrate malabsorption was 19%, and
fat malabsorption was 51%. Moreover, the age group of 0-11
months had a 1.5 times greater possibility of lactose and fat
malabsorption compared to that of 12-59 months. The 12-59 months
age group had a greater possibility of suffering carbohydrate
maldigestion (70%). The group of children who did not suffer
from bacterial infection had a higher prevalence of lactose mal-
absorption (54%), carbohydrate maldigestion (65%), and fat
malabsorption (58%).
Conclusions Acute diarrhea occurred more frequently in the
age of 0-11 months. There was a significant correlation between
the age groups of 0-11 months and 12-59 months in experiencing
macronutrient malabsorption. Lactose malabsorption, carbohy-
drate maldigestion, and fat malabsorption were encountered more
frequently in the group that did not have bacterial infection

Author Biographies

Lilis D. Hendrawati
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Agus Firmansyah
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Darlan Darwis
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

References

1. Noerasid H, Suraatmadja S, Asril PO. Gastroenteritis
(diare) akut. In: Suharyono, Boediarso A, Halimun EM,
editors. Gastroenterologi anak praktis. 2nd ed. Jakarta:
Gaya Baru; 1994. p. 51-83.
2. Firmansyah A. Pemahanan atas konsep perkembangan
saluran cerna dalam upaya menurunkan morbiditas diare
pada anak [dissertation]. Jakarta (Indonesia): Medical
School, Univ. Indonesia; 1997.
3. Ariyani A. Gambaran diare akut serta hubungannya
dengan gejala yang ditemukan pada anak 0-2 tahun
yang dirawat di SMF Anak RSUPN CM periode Sep-
tember 1996 – Januari 1997 [thesis]. Jakarta (Indone-
sia): Clinical Pathology Department, Medical School,
Univ. Indonesia; 1998.
4. Suharyono. Literature review: Maldigesti dan malabsorpsi.
In: Diare akut. Jakarta: Lembaga Penerbit Fakultas
Ekonomi Universitas Indonesia; 1986. p.23-9.
5. Suharyono, Sunoto, Sutedjo. Lactose intolerance in In-
donesian children. Ann Inst Child Health 1971;1:7.
6. Mustadjab L, Munir M. Lactose intolerance in patients
with gastroenteritis between 0-2 years of age. Paediatr
Indones 1976;16:415-20.
7. Hegar B, Firmansyah A. Evaluasi penderita diare yang
dirawat di bangsal anak RSCM 1994. Maj Kes Masy
Indones 1995;8:563-5.
8. Suharyono. Literature review: Penelitian gangguan
fungsi saluran pencernaan makanan. In: Diare akut.
Jakarta: Lembaga Penerbit Fakultas Ekonomi Universi-
tas Indonesia; 1986. p. 23-9.
9. Suharyono. Penanggulangan diare akut pada bayi dan
anak di Jakarta dan masalahnya [doctoral thesis]. Jakarta
(Indonesia): Medical School, Univ. Indonesia; 1985.
10. Bass DM. Rotavirus and other agents of viral gastroen-
teritis. In: Nelson WE, Berhman RE, Kliegman RM, Arvin
AM, editors. Nelson’s textbook of pediatrics. 17th ed.
Philadelphia: WB Saunders; 2000. p. 765 – 8.
11. Webberley. Travellers’ diarrhea. In: Bouchier IA, Allan
RN, editors. Gastroenterology clinical science and prac-
tice. 2nd ed. Philadelphia: WB Saunders; 1993. p. 1425-8.
Published
2016-10-13
How to Cite
1.
Hendrawati L, Firmansyah A, Darwis D. Macronutrient malabsorption in acute diarrhea: Prevalence and affecting factors. PI [Internet]. 13Oct.2016 [cited 22Nov.2024];45(5):207-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/841
Received 2016-10-10
Accepted 2016-10-10
Published 2016-10-13