Lactose malabsorption in junior high school children

  • Aswitha D. Budiarso
  • Deny Sofia
  • Sri Rezeki S Hadinegoro
  • Badriul Hegar
Keywords: lactose malabsorption, lactose intolerance, breath hydrogen test, milk drinking habit

Abstract

Background The prevalence of lactose malabsorption varies
widely throughout the world. Only people of Caucasian genetic
background continue to produce high amount of lactase throughout
adulthood. Previous studies in Indonesia revealed that the
prevalence of lactose malabsorption was 21-58% in children aged
3-11 years.
Objective To determine the prevalence of lactose malabsorption
in the older age group and whether a change in milk drinking habit
can affect it.
Methods A cross sectional descriptive study was conducted on
98 children aged between 12 and 14 years (junior high school) in
Jakarta. Lactose malabsorption was evaluated with Lactometer
Breath Hydrogen Test (Hoek Loes, Amsterdam). Milk drinking habit
was recorded, and drinking at least 1 glass of milk everyday since
6 months or more before the study was considered as regular milk
drinking.
Results This study showed 73% of the children had lactose malabsorption.
Regular milk drinking habit was found in 32 (33%) children
and lactose malabsorption occurred in 26. From 66 children
who were irregular milk drinkers, lactose malabsorption was found
in 46 (70%). Lactose intolerance was about the same in both groups.
Conclusion There was an increasing prevalence of lactose malabsorption
in older children. Milk drinking habit is a major concern
to review the practical implications of lactose malabsorption.

Author Biographies

Aswitha D. Budiarso
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta.
Deny Sofia
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta.
Sri Rezeki S Hadinegoro
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta.
Badriul Hegar
Department of Child Health, Medical School, University of
Indonesia, Cipto Mangunkusumo Hospital, Jakarta.

References

1. Lebenthal E, Kretchmer N, Alliet P. Lactase deficiency,
lactose malabsorption and lactose intolerance. In:
Lebenthal E, editor. Texbook of gastroenterology and
nutrition in infancy. New York: Raven Press; 1989. p.
459-72.
2. Buller HA. Lactase phlorizin hydrolase: A review of
the literature [dissertation]. Amsterdam: University of
Amsterdam; 1990.
3. Hegar B. Uji hidrogen napas satu cara diagnostik
gangguan saluran cerna. Maj Kes Masy Indones 1998;
3:278-80.
4. Hegar B, Buller HA. Breath hydrogen test in lactose
malabsorption. Paediatr Indones 1995; 35:161-71.
5. Kerzner B. Breath tests. In: Wyllie R, Hyams JS, editors.
Pediatric gastrointestinal disease pathophysiology,
diagnosis, management. Philadelphia: WB Saunders;
1993. p. 1027-37.
6. Hegar B, Firmansyah A, Boediarso A, Sunoto. Aktivitas
enzim laktase pada murid taman kanak-kanak. Maj Kes
Masy Indones 1997;2:125-7.
7. Hegar B, Niken PY, Pramita G. Aktivitas enzim laktase
pada murid sekolah dasar. Maj Kes Masy Indones
2000;4:723-5.
8. Rings E, Grand RJ, Buller HA. Lactose intolerance
and lactase deficiency in children. Curr Opin Pediatr
1994;6:562-7.
9. Quak SH. Accuracy of lactose breath hydrogen analysis
in the diagnosis of lactase deficiency. Int Med J
1998;5:47-9.
10. American Academy of Pediatric. Committee on Nutrition:
The practical significance of lactose intolerance
in children. Pediatrics 1978;62:240-5.
11. Nose O, Lida Y, Kai H. Breath hydrogen test for detecting
lactose malabsorption in infants & children.
Arch Dis Child 1979;54:436-40.
12. Tadesse K, Leung PT, Yuen RC. The status of lactose
absorption in Hong Kong Chinese children. Acta
Paediatr 1992;81:598-600.
13. Schmitz J. Malabsorption. In: Walker WA, Durie PR,
Hamilton JR, Walker-Smith JA, editors. Pediatric gastrointestinal
disease. St-Louis: Mosby; 1996. p. 83-95.
14. Welle AR. Carbohydrate intolerance. In: Roy CC,
Silverman A, Alagille D, editors. Pediatric clinical gastroenterology.
St Louis: Mosby; 1994. p. 287-98.
15. Bolin TD, Pirola RC, Davis AE. Adaptation of intestinal
lactase in the rat. Gastroenterology
1969;60:432-7.
16. Bolin TD, Davis AE. Primary adult lactase deficiency:
genetic or aquired? Am J Digest Dis 1970;15:692-769.
17. Lebenthal E, Sunshine P, Kretcmer N. Effect of prolonged
nursing on the activity of intestinal lactase in
rats. Gastroenteorology 1973;64:1136-41.
18. Woteki CE, Weser E, Young EA. Lactose malabsorption
in Mexican-American children. Am J Clin Nutr
1976;29:19.
19. Lisker R, Lopez-Habib G, Daltabuit M. Lactose deficiency
in a rural area of Mexico. Am J Clin Nutr
1974;27:756.
20. Stephenson LS, Latham MC. Lactose intolerance and
milk consumption. The relation of tolerance to symptoms.
Am J Clin Nutr 1974;27:296.
21. Newcomer AD, Thomas PJ, McGill DB, Hoffman AF.
Lactose deficiency: A common genetic trait of the
American Indian. Gastroenterology 1977;72:234.
22. Labenthal E, Antonowicz I, Schwachman H. Correlation
of lactase activity, lactose intolerance, and milk
consumption in different age groups. Am J Clin Nutr
1976;28:595.
23. Kretchmer N. Memorial lecture: Lactose and lactase a
historical perspective. Gastroenterology 1971;6:805-13.
24. Knudsen KB, Wels JD, Kronenberg RS, Vanderveen
JE, Heidelbaugh ND. Effect of a nonlactose diet on
human intestinal disacharidase activity. Am J Digest
Dis 1968;13:593-7.
25. Kogut MD, Donnell GN, Shaw KNF. Studies of lactose
absorption in patients with galactosemia. J Pediatr
1967;7:75-81.
26. Suharjono, Sunoto, Boediarso A, Sutedjo. Lactose malabsorption
in healthy Indonesian pre-school children.
Paediatr Indones 1971;11:251-4.
27. Surjono A, Sebodo T, Sunarto J, Moenginah PA. Lactose
intolerance among healthy adults. Paediatr
Indones 1973;13:49-54.
28. San Diego PC, Iskandar A. Lactose Intolerance in an
Indonesian closed community. Paediatr Indones
1974;14:92-105.
Published
2016-10-10
How to Cite
1.
Budiarso A, Sofia D, Hadinegoro S, Hegar B. Lactose malabsorption in junior high school children. PI [Internet]. 10Oct.2016 [cited 28May2024];43(2):46-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/838
Section
Articles
Received 2016-10-10
Accepted 2016-10-10
Published 2016-10-10