Mortality predictors of pneumonia in children

Main Article Content

Priyanti Kisworini
Amalia Setyati
Sutaryo Sutaryo

Abstract

Background Pneumonia is one of the main causes of death in children in developing countries. It is important to identify clinical signs, demographic factors, and laboratory data which can be used to predict children who have higher risk of mortality from pneumonia.

Objective To find the clinical signs, demographic factors and laboratory data that can be used as predictors of mortality from pneumonia.


Methods T his historical case􀀽control study was carried out in Sardjito Hospital between January 2004 and December 2006. Data were obtained from medical records. Differential proportion between groups was analyzed with chi square. Regression analysis was used to identify clinical factors, demographic factors and laboratory factors that associated with mortality from pneumonia.

Results Fifty􀀽eight patients were enrolled in this study, 29 patients were dead (case group) and 29 patients were cured (control group). Baseline data between the two groups were similar in terms of gender and mean of age. Bivariate analyses show that the predictors of mortality in children with pneumonia were: age < 1 year (OR3.11, 95% CI 1.06 to 9.08), malnutrition (OR 7.30,95% CI 1.62- to 21.03), age of the mother < 20 years (OR 2.21,95%
CI 1.64 to 2.97),t achycardia (OR 6.075,95% CI 1.18 to 31.24), and anemia (OR 5 .83, 95% CI 1.88 to 18.10). Logistic regression analysis shows that tachycardia (OR 6.04, 95% CI 1.01 to 36.17) and anemia (OR 4.41,95% CI 1.25 to 15.51) were predictor of mortality in children 'With pneumonia.

Conclusions Tachycardia and anemia play as independent mortality predictors of pneumonia in children.

Article Details

How to Cite
1.
Kisworini P, Setyati A, Sutaryo S. Mortality predictors of pneumonia in children. PI [Internet]. 30Jun.2010 [cited 19Aug.2019];50(3):149-3. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/812
Section
Articles
Received 2016-10-06
Accepted 2016-10-06
Published 2010-06-30

References

1. WHO, Geneva. Technical bases for the WHO recommendations on the management of pneumonia in children at firsdevel health faciliteis In : Programme for control of acute respiratory infection, 1990.
2. Dowell SF. Kupronis BA. Zell ER, Shay DK. Mortality from pneumonia in children in the United States, 1939 through 1996. N Eng J Med. 2000;342,1399-407.
3. Gunajaya E, Widia 1M. Clinical predictors of hypoxemia in pneumonia. Pediatr Indones. 2003;43:192-7.
4. Lodha R, Bhadauria PS, Kuttikat A V, Puranik M, Gupta S, Pandey RM, et aL Can clinical symptoms or sign accurately predict hypoxemia in children 'With acute lower respiratory tract infections? Indian Pediatrics. 2004;41:129-35.
5. Stekelenburg J, Kashumba E, Wolffers. Factors contributing to high mortality due to pneumonia among under-fives in Kalabo District, Zambia. Trop Med Int Health. 2002;7:886-93.
6. Said M. Pneumonia penyebab utama mortalitas anak balita di Indonesia. Bul IDA!. 2006;45:13-4.
7. Kartasasmita CB, Mintardaningsih, Rosmayudi 0, Suardi AU, Sukandar H. Community trials on case management of acute respiratory infections (ARI) in rural villages. Paediatr Indones. 2001;41:260.3.
8. West TE. Goetghebuer T. Milligan P, Mulholland EK. Weber MW Long􀁨tenn morbidity and mortality following hypoxaemic lower respiratory tract Infection in Gambian children. Bull World Health Organ. 1999;77,144·8
9. Nathoo KJ. Nkrumah FK. Ndlovu D. Nhembe M. Pirie DJ, Kowo H. Acute lower respiratory tract infection in hospitalized children in Zimbabwe. Ann Trop Paediatr. 1993; 13,253-61.
10. Sehgal V, Sethi GR, Sachdev HP, Satyanarayana L. Predictors of mortality in subjects hospitalized with acute lower respiratory tract infections. Indian Pediatr. 1997 ;34:213-9.
11 Vejar L, Casteran JC, Navarette P, Sanchesz S, LeCerf P, Castillo C. Risk factors for home deaths due to pneumonia among low socioeconomic level Chilean children, Santiago de Chile. Rev Med Chi!. 2000;128,627-32.
12. Suwanjutha S, Ruangkancha-nasetr S, Chantarojanasiri T,
Hotrakitya S. Risk factors associated with morbidity and mortality of pneumonia in Thai children under 5 years. Southeast Asian J Trop Med Public Health. 1994;25:60·6.
13. lvijanthi MQ, Vitri S, Landia S, Makmuri MS. Risk factors of mortality in children under 6-year-old with pneumonia. Presented at 13th Child Health National Congress, Bandung, 2005.
14. Sastroasmoro S, Ismael S. Dasar-dasar metodologi penelitian klinis. 2nd ed. Jakarta:' CV Sagung Seto, 2000.
15. Gunajaya E, Widia 1M. Clinical predictors of hypoxemia in pneumonia. Pediatr Indones. 2003;43:192-7.
16. Usen S. Weber M. Mulholland EK. Jaffar S. Oparaugo A, Omosigho C, et al. Clinical predictors of hypoxaemi in Gambian children with acute lower respiratory tract infection: prospective cohort study. BMJ. 1999;518:86-91.
17. Weber MW, Usen S. Palmer A, Jaffar S. Mulholland EK. Predictors of hypoxaemia in hospital admissions with acute lower respiratory tract infection in a developing country. Arch Dis Child. 1997;76,310-4.
18. Scrimshaw NS and SanGiovanni JP. Synergism of nutrition, infection and immunity: an overview. Am J Clin Nutr. 1997;66,S464· 77.