Association between soil-transmitted helminthiasis and hemoglobin concentration in primary school children
Keywords:
helminthiasis, Hb concentration, albendazole treatment, anemia
Abstract
Objectives To determine the association between intestinal hel-minthiasis and hemoglobin (Hb) concentration and to observe the
effect of single dose albendazole treatment on Hb concentration.
Methods An experimental study was carried out from March to
July 2002 on primary school children at Suka Village, Tiga Panah
Subdistrict, Karo Regency, North Sumatera Province. From 366
children who suffered from helminthiasis, 113 were selected as
subjects by simple random sampling. Subjects were treated with a
single oral dose of 400 mg albendazole. Hb concentration was
examined using the cyanide method twice i.e., prior to and three
months after treatment with albendazole.
Results It was found that among 113 subjects, the prevalences of
Ascaris lumbricoides, Trichuris trichiura, and mixed infestation were
18.3%, 40.4%, and 41.3%, respectively, while the prevalence of
anemia was 33.0%. There was no significant difference in age,
gender, nutritional status, and mean Hb concentration between
children suffering from the different types of worm infestation
(P>0.05). For each type of infestation, there were significant differ-
ences in mean Hb concentration and anemia prevalence before
and after treatment (P<0.05).
Conclusions There was no difference between the Hb concen-
trations of children suffering from Ascaris lumbricoides, Trichuris
trichiura, and mixed-type worm infestations. Single dose 400 mg
albendazole was beneficial in increasing Hb concentration and
reducing the occurrence of anemia
References
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testinal tract (Enterobius vermicularis, Trichuris trichiura,
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hookworms. Am J Clin Nutr 1997;65:153-9.
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parasitologi. Medan: Pendidikan Analis Kesehatan
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19. Pasaribu S, Lubis CP. Diagnostic of hookworm infec-
tion by using modified Kato-Katz thick smear. Proceed-
ings of the Congress of Infectious Diseases; 1996; Kuala
Lumpur, Malaysia.
20. Nallam NR, Paul I & Gnanamani G. Anemia and hy-
poalbuminemia as an adjunct to soil-transmitted hel-
minthiasis among slum school children in
Visakhapatnam. South India, Asia Pacific J Clin Nutr
1998;7:164-9.
21. Smith HM, De Kaminsky RG, Niwas S, Soto RJ, Jolly
PE. Prevalence and intensity of infections of Acaris
lumbricoides and Trichuris trichiura and associated socio-
demographic variables in four rural Honduran com-
munities. Mem Inst Oswaldo Cruz, Rio de Janeiro
2001;96:303-14.
22. Norhayati M, Zainudin B, Mohammod CG, Oothuman
P, Azizi O, Fatmah MS. The prevalence of Trichuris,
Ascaris and hookworm infection in Orang Asli chil-
dren. Southeast Asian J Trop Med Public Health
1997;28:161-8.
23. Greenberg ER, Cline BL. Is trichuriasis associated with iron
deficiency anemia? Am J Trop Med Hyg 1979;28:770-2.
24. Blumenthal DS & Schultz MG. Effects of Ascaris in-
fection on nutritional status in children. Am J Trop
Med Hyg 1976;25:682-90.
25. Robertson LJ, Crompton DWT & Nesheim MC. He-
moglobin concentration and concomitant infections
of hookworm and Trichuris trichiura in Panamanian
primary school children. Transactions of the Royal
Society of Tropical Medicine and Hygiene 1992;
86:654-6.
26. Stoltzfus RJ, Albonico, Chwaya M, Savioli L, Tielsch
J, Schulze K, et al. Hemoquant determination of
hookworm-related blood loss and its in iron defi-
ciency in African children. Am J Trop Med Hyg
1996;55:399-404.
27. Oguntibeju OO. Parasitic infection and anemia: the
prevalence in a rural hospital setting. JIACM
2003;210-2.
massal askariasis dengan albendazole pada anak usia
sekolah dasar [dissertation]. Medan: University of
Sumatera Utara; 2004.
2. Mahmoud AAF. Intestinal nematodes. In: Mandell
GL, Bennett JE, Dolin R, editors. Mandell, Douglas,
and Bennett’s principles and practice of infectious
disease. 5th ed. New York: Churchill Livingstone;
2000. p. 2938-9.
3. Margono SS. Nematoda usus. In: Gandahusada S,
Ilahude HD, Pribadi W, editors. Parasitologi
kedokteran. 3rd ed. Jakarta: Fakultas Kedokteran Uni-
versitas Indonesia; 1998. p. 8-34.
4. Strickland GT. General principles. In: Hunters’ tropi-
cal medicine. 8th ed. Philadelphia: WB Saunders Com-
pany; 2000. p. 722-4.
5. Bundy DAP, DeSilva N. Intestinal nematodes that mi-
grate through lungs (ascariasis). In: Strickland GT, edi-
tor. Hunters’ tropical medicine. Philadelphia: WB
Saunders Company; 2000. p. 726-30.
6. Kazura JW. Ascariasis. In: Behrman RE, Kliegman RM,
Arvin AM, editors. Nelson textbook of pediatrics. 15th ed.
Philadelphia: WB Saunders Company; 1996. p. 992-3
7. Bundy DAP, Cooper E. Nematodes limited to the in-
testinal tract (Enterobius vermicularis, Trichuris trichiura,
and Capillaria phillippinensis). In: Strickland GT, edi-
tor. Hunters’ tropical medicine. 8th ed. Philadelphia:
WB Saunders Company; 2000. p. 719-24.
8. Warren KS, Bundy DAP, Anderson RM, et al. Helm-
inth infection. In: Jamison DT, Mosley WH, Measham
AR, Bobadilla JL, editors. Disease control priorities in
developing countries. New York: Oxford University
Press; 1993. p. 131-60.
9. Ozumba UC, Ozumba N. Patterns of helminth infec-
tion in the human at the university of Nigeria teaching
hospital, Enugu, Nigeria. J Health Sci 2002;48:263-8.
10. Gilman RH. Intestinal nematodes that migrate through
skin and lung. In: Strickland GT, editor. Hunters’ tropi-
cal medicine. 8th ed. Philadelphia: WB Saunders Com-
pany; 2000. p. 730-5.
11. King CH. Hookworms. In: Behrman RE, Kliegman RM,
Arvin AM, editors. Nelson textbook of pediatrics. 15th
ed. Philadelphia: WB Saunders Company; 1996. p.
1000-1.
12. Committee on infectious diseases. Hookworm infec-
tions. In: Pickering LK, Peter G, Baker CJ, Gerber MA,
MacDonald NE, editors. 2000 red book: report of the
committee on infectious diseases. 25th ed. Elk Grove
Village: American Academy of Pediatrics; 2000. p. 321.
13. Stlotzfus RJ, Dreyfuss ML, Chwaya HM, Albanico M.
Hookworm control as a strategy to prevent iron defi-
ciency. Nutrition Reviews 1997;55:223-32.
14. Stlotzfus RJ, Chwaya HM, Tielsch JM, Schulze KJ,
Albanico, Savioli L. Epidemiology of iron deficiency
anemia in Zanzibar schoolchildren: the importance of
hookworms. Am J Clin Nutr 1997;65:153-9.
15. Sembiring TUJ. Protozoologi dan penuntun praktikum
parasitologi. Medan: Pendidikan Analis Kesehatan
Depkes RI; 1997. p. 131-5.
16. Kuczmarski RJ, Ogden CL, Grumer-Strawn LG. CDC
growth charts: United States. Advanced data–NCHS
2000;314:1-28.
17. Bain BJ, Bates I. Basic haematological techniques. In:
Lewis SM, Bain BJ, Bates I, editors. Dacie and Lewis
practical hematology. 9th ed. London: Churchill
Livingstone; 2001. p. 19-33.
18. Dirren H, Logman MH, Barclay DV, Freire WB. Alti-
tude correction for hemoglobin. Eur J Clin Nutr
1994;48:625-32.
19. Pasaribu S, Lubis CP. Diagnostic of hookworm infec-
tion by using modified Kato-Katz thick smear. Proceed-
ings of the Congress of Infectious Diseases; 1996; Kuala
Lumpur, Malaysia.
20. Nallam NR, Paul I & Gnanamani G. Anemia and hy-
poalbuminemia as an adjunct to soil-transmitted hel-
minthiasis among slum school children in
Visakhapatnam. South India, Asia Pacific J Clin Nutr
1998;7:164-9.
21. Smith HM, De Kaminsky RG, Niwas S, Soto RJ, Jolly
PE. Prevalence and intensity of infections of Acaris
lumbricoides and Trichuris trichiura and associated socio-
demographic variables in four rural Honduran com-
munities. Mem Inst Oswaldo Cruz, Rio de Janeiro
2001;96:303-14.
22. Norhayati M, Zainudin B, Mohammod CG, Oothuman
P, Azizi O, Fatmah MS. The prevalence of Trichuris,
Ascaris and hookworm infection in Orang Asli chil-
dren. Southeast Asian J Trop Med Public Health
1997;28:161-8.
23. Greenberg ER, Cline BL. Is trichuriasis associated with iron
deficiency anemia? Am J Trop Med Hyg 1979;28:770-2.
24. Blumenthal DS & Schultz MG. Effects of Ascaris in-
fection on nutritional status in children. Am J Trop
Med Hyg 1976;25:682-90.
25. Robertson LJ, Crompton DWT & Nesheim MC. He-
moglobin concentration and concomitant infections
of hookworm and Trichuris trichiura in Panamanian
primary school children. Transactions of the Royal
Society of Tropical Medicine and Hygiene 1992;
86:654-6.
26. Stoltzfus RJ, Albonico, Chwaya M, Savioli L, Tielsch
J, Schulze K, et al. Hemoquant determination of
hookworm-related blood loss and its in iron defi-
ciency in African children. Am J Trop Med Hyg
1996;55:399-404.
27. Oguntibeju OO. Parasitic infection and anemia: the
prevalence in a rural hospital setting. JIACM
2003;210-2.
Published
2016-10-10
How to Cite
1.
Angraini R, Dimyati Y, Lubis B, Pasaribu S, Lubis C. Association between soil-transmitted helminthiasis and hemoglobin concentration in primary school children. PI [Internet]. 10Oct.2016 [cited 22Nov.2024];45(1):24-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/794
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Received 2016-10-05
Accepted 2016-10-05
Published 2016-10-10
Accepted 2016-10-05
Published 2016-10-10
