Cow’s milk allergy in patients with diarrhea
Keywords:
cow’s milk allergy, diarrhea, partially hydrolyzed formula, extensively hydrolyzed formula
Abstract
Background Cow’s milk allergy (CMA) might be one of the causesof diarrhea in children. Previous prospective studies found the
prevalence of CMA in children aged 0-3 years between 1.1-5.2%,
but data about the prevalence of CMA in children with diarrhea
was very limited.
Objective This study intended to estimate the prevalence of CMA
in children with diarrhea.
Methods Children aged 0-3 years, who came with diarrhea and
consumed milk formula were selected for further evaluation. A
diagnostic procedure was developed i.e., elimination diet with par-
tially hydrolyzed formula (pHF) for 2 weeks, and then open milk
challenge. If diarrhea was not resolved with pHF, the children were
given extensively hydrolyzed formula, or soy-based formula.
Results Ninety-nine children participated in this study, 87 came
with acute diarrhea and 12 with chronic diarrhea. There were 3
children (2 children with acute diarrhea and one with chronic
diarrhea) who reacted to the milk challenge.
Conclusion The estimated prevalence of CMA in children with
diarrhea in our study was 3%
References
1. Noerasid H, Suraatmadja S, Asnil PO. Gastroenteritis
(diare) akut. In: Suharyono, Boediarso A, Halimun EM,
editors. Gastroenterologi anak praktis. 2 nd ed. Jakarta:
BP-FKUI; 1994. p. 51-76.
2. Suharyono. Diare kronik. In: Suharyono, Boediarso A,
Halimun EM, editors. Gastroenterologi anak praktis.
2 nd ed. Jakarta: BP-FKUI; 1994. p. 85-96.
3. Sampson HA. Food Allergy. JAMA 1997;278:1888-94.
4. Moon A, Kleinman RE. Allergic gastroenteropathy in
children. Ann Allergy Asthma Immunol 1995;74:5-12.
5. Harsono A. Alergi makanan. In: Akib AAP,
Matondang CS, editors. Buku ajar alergi-imunologi anak.
Jakarta: BP IDAI; 1996. p. 204-13.
6. Saarinen KM, Juntunen-Backman K, Jarvenpaa AL.
Supplementary feeding in maternity hospitals and the
risk of cow‘s milk allergy: a prospective study of 6209
infants. J Allergy Clin Immunol 1999;104: 457- 61.
7. Bocks SA. Prospective appraisal of complaints of ad-
verse reactions to food in children during the first 3
years of life. Pediatrics 1987;79:683-8.
8. Host A, Halken S, Jakobsen HP, Christensen HP,
Herskind AM, Plesner K. Clinical course of cow’s milk
protein allergy/intolerance and atopic diseases in child-
hood. Pediatr Allergy Immunol 2002;13:23-8.
9. Eggesbo M, Botten G, Halvoren R, Magnus P. The preva-
lence of CMA/CMPI in young children: the validity of
parentally perceived reactions in a population-based study.
Allergy 2001;56:393-402.
10. Hill DJ, Firer MA, Shelton MJ, Hosking CS. Manifesta-
tions of milk allergy in infancy: clinical and immuno-
logic findings. J Pediatr 1986;109:270-6.
11. Host A, Koletzko B, Dreborg S, Muraro A, Wahn U, Agget
P, et al. Dietary products used in infants for treatment and
prevention of food allergy: joint statement of the Euro-
pean Society for Pediatric Allergology and Clinical
Immunollogy (ESPACI) Committee on hypoallergenic
formulas and the European Society for Pediatric Gastro-
enterology, Hepatology and Nutrition (ESPGHAN) Com-
mittee on Nutrition. Arch Dis Child 1999;81:80-4.
12. Zeiger RS. Food allergen avoidance in the prevention of food
allergy in infants and children. Pediatrics 2003;111:1662-71.
13. Host A. Frequency of cow’s milk allergy in childhood.
Ann Allergy Asthma Immunol 2002;89:33-7.
(diare) akut. In: Suharyono, Boediarso A, Halimun EM,
editors. Gastroenterologi anak praktis. 2 nd ed. Jakarta:
BP-FKUI; 1994. p. 51-76.
2. Suharyono. Diare kronik. In: Suharyono, Boediarso A,
Halimun EM, editors. Gastroenterologi anak praktis.
2 nd ed. Jakarta: BP-FKUI; 1994. p. 85-96.
3. Sampson HA. Food Allergy. JAMA 1997;278:1888-94.
4. Moon A, Kleinman RE. Allergic gastroenteropathy in
children. Ann Allergy Asthma Immunol 1995;74:5-12.
5. Harsono A. Alergi makanan. In: Akib AAP,
Matondang CS, editors. Buku ajar alergi-imunologi anak.
Jakarta: BP IDAI; 1996. p. 204-13.
6. Saarinen KM, Juntunen-Backman K, Jarvenpaa AL.
Supplementary feeding in maternity hospitals and the
risk of cow‘s milk allergy: a prospective study of 6209
infants. J Allergy Clin Immunol 1999;104: 457- 61.
7. Bocks SA. Prospective appraisal of complaints of ad-
verse reactions to food in children during the first 3
years of life. Pediatrics 1987;79:683-8.
8. Host A, Halken S, Jakobsen HP, Christensen HP,
Herskind AM, Plesner K. Clinical course of cow’s milk
protein allergy/intolerance and atopic diseases in child-
hood. Pediatr Allergy Immunol 2002;13:23-8.
9. Eggesbo M, Botten G, Halvoren R, Magnus P. The preva-
lence of CMA/CMPI in young children: the validity of
parentally perceived reactions in a population-based study.
Allergy 2001;56:393-402.
10. Hill DJ, Firer MA, Shelton MJ, Hosking CS. Manifesta-
tions of milk allergy in infancy: clinical and immuno-
logic findings. J Pediatr 1986;109:270-6.
11. Host A, Koletzko B, Dreborg S, Muraro A, Wahn U, Agget
P, et al. Dietary products used in infants for treatment and
prevention of food allergy: joint statement of the Euro-
pean Society for Pediatric Allergology and Clinical
Immunollogy (ESPACI) Committee on hypoallergenic
formulas and the European Society for Pediatric Gastro-
enterology, Hepatology and Nutrition (ESPGHAN) Com-
mittee on Nutrition. Arch Dis Child 1999;81:80-4.
12. Zeiger RS. Food allergen avoidance in the prevention of food
allergy in infants and children. Pediatrics 2003;111:1662-71.
13. Host A. Frequency of cow’s milk allergy in childhood.
Ann Allergy Asthma Immunol 2002;89:33-7.
Published
2016-10-10
How to Cite
1.
Marzuki N, Akib A, Boediman I. Cow’s milk allergy in patients with diarrhea. PI [Internet]. 10Oct.2016 [cited 23Apr.2024];44(6):239-2. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/785
Section
Articles
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Received 2016-10-03
Accepted 2016-10-03
Published 2016-10-10
Accepted 2016-10-03
Published 2016-10-10
