Cow’s milk allergy in patients with diarrhea
Abstract
Background Cow’s milk allergy (CMA) might be one of the causesof diarrhea in children. Previous prospective studies found the
prevalence of CMA in children aged 0-3 years between 1.1-5.2%,
but data about the prevalence of CMA in children with diarrhea
was very limited.
Objective This study intended to estimate the prevalence of CMA
in children with diarrhea.
Methods Children aged 0-3 years, who came with diarrhea and
consumed milk formula were selected for further evaluation. A
diagnostic procedure was developed i.e., elimination diet with par-
tially hydrolyzed formula (pHF) for 2 weeks, and then open milk
challenge. If diarrhea was not resolved with pHF, the children were
given extensively hydrolyzed formula, or soy-based formula.
Results Ninety-nine children participated in this study, 87 came
with acute diarrhea and 12 with chronic diarrhea. There were 3
children (2 children with acute diarrhea and one with chronic
diarrhea) who reacted to the milk challenge.
Conclusion The estimated prevalence of CMA in children with
diarrhea in our study was 3%
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Accepted 2016-10-03
Published 2016-10-10