Comparison of clinical aspects and Mantoux test in tuberculosis versus non-tuberculosis superficial lymphadenitis
Keywords:
Clinical aspect, Mantoux test, tuberculosis superficial lymphadenitis, fine needle aspirate
Abstract
Objective To investigate the clinical aspects and result of Man-toux test in superficial lymphadenitis caused by Mycobacterium
tuberculosis (MTB) compared to that caused by non-MTB organ-
isms.
Methods This was a cross sectional study conducted on 86 pa-
tients aged between 3 months and 14 year-old with enlargement
of the superficial lymph nodes, 43 with tuberculosis superficial lym-
phadenitis (TSL) and 43 with non-tuberculosis superficial lymphad-
enitis (NTSL). The diagnoses of TSL and NTSL were confirmed by
histopathological examination. Clinical symptoms and Mantoux test
were examined in this study.
Results In the TSL group, most children (70%) were in the age of
>5-14 year-old, while in the NTSL, most (46%) were 1-5 years old.
The most frequent chief complaint in the TSL group was fever
(37%), while in the NTSL group, cough (49%) (p=0.004). Failure to
thrive and loss of appetite were more frequently found in the TSL
(70% and 35%) compared to the NTSL group (0 and 3%) (p=0.004).
Most enlarged nodes in TSL were multiple (67%), while in NTSL,
solitary (72%) (p<0.001). There were no differences in the location
and distribution of enlarged nodes between the two groups. Thirty-
one (72%) children in the TSL group had positive Mantoux test,
while in the NTSL group were only 2(5%) (p<0.001).
Conclusions Most children with TSL had fever as the chief com-
plaint while those with NTSL had cough. Children with TSL had
failure to thrive, loss of appetite, multiple nodes, and positive Man-
toux test more frequently compared to NTSL ones
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phadenitis. Acta Cytologica 1992;36:391-4.
17. Rahajoe NN. Challenges of tuberculosis diagnosis and
management in children. KONIKA XII; Bali, Indonesia.
18. Thompson MM, Underwood MJ, Sayers RD,
Dookeran KA, Bell PRF. Peripheral tuberculosis
lymphadenop-hathy: review of 67 cases. Br J Surg
1992;79:763-4.
19. Lau SK, Wei WI, Engzell UCG. Efficacy of fine
needle aspiration cytology in the diagnosis of tuber-
culosis cervical lymphadenopathy. J Laryngo Otol
1990;104: 24-7.
JIE, Rudolph CD, editors. Rudolph’s pediatrics. 20 th
ed. New York: Prentice Hall Int; 1996. p. 614-23.
2. Jha BC, Dass A, Nagarkar NM, Gupta R, Singhal S.
Cervical tuberculosis lymphadenophathy: changing
clinical pattern and concepts in management. Postgard
Med 2001;77:185-7.
3. Khan EA, Starke JR. Diagnosis of tuberculosis in chil-
dren increased need better methods. Baylor College of
Medicine 1997; 1:1-13.
4. Small PM, Selcer UM. Tuberculous adenitis. In:
Strickland GT, editor. Tropical medicine and emerg-
ing infectious diseases. 8 th ed. Philadelphia: Saunders;
2001. p. 499.
5. Inselman LS, Kendig EL. Tuberculosis of the superfi-
cial lymph nodes. In: Chernick V, Kendig EL, editors.
Disorders of the respiratory tract in children. 5 th ed.
Philadelphia: Saunders; 1990. p. 759-60.
6. Loenhout-Rooyackers JH, Laheji RJF, Richter C,
Verbeek ALM. Shortening the duration of treatment
for cervical tuberculosis lymphadenitis. Eur Respir L
2000;15:192-5.
7. Starke JR. Tuberculosis. In: Behrman RE, Kliegman
RM , Arvin AM, editors. Nelson textbook of pediat-
rics. 16 th ed. Philadelphia: Saunders; 1996. p. 34-47.
8. Cambell I, Drobniewski F, Novelli V, Ormerod P,
Pozniak A. Management of opportunist mycobacterial
infection: joint tuberculosis committee guideline 1999.
Thorax 2000;55:210-8.
9. Rahajoe NN. Tatalaksana tuberkulosis pada anak. Sari
pediatri 2001;3: 24-35.
10. Dandapat MC, Mishra BM, Dash SP, Kar PK. Periph-
eral lymph node tuberculosis: a review of 80 cases. Br J
Surg 1990;77:911-2.
11. Geldmacher H, Taube C, Kroeger C, Magnussen H,
Kirsten DK. Assessment of lymph node tuberculosis
in northern Germany. Chest 2002;121(4):1177-82.
12. Mignogna MD, Muzio LLO, Favia G. Oral tubercu-
losis: a clinical evaluation of 42 cases. Oral Disease
2000;6:25-30.
13. Manolidis S, Frenkiel S, Yoscovitch A, Black M. My-
cobacterial infections of the head and neck.
Otolaryngol head neck surg 1993;109:427-33.
14. Castro JJ, Hoover L, Castro DJ, Zuckerbraun L. Cervi-
cal mycobacterial lymphadenitis. Arch Otolaryngol
1985;111:816-9.
15. Hopewell PC, Bloom BR. Tuberculosis and other my-
cobacterial disease. In: Murray JF, Nadel JA, editors.
Textbook of respiratory medicine. 3 rd ed. Philadelphia:
Saunders; 1996. p. 34-47.
16. Gupta AK, Nayar M, Chandra M. Critical appraisal
of fine needle aspiration cytology in tuberculosis lym-
phadenitis. Acta Cytologica 1992;36:391-4.
17. Rahajoe NN. Challenges of tuberculosis diagnosis and
management in children. KONIKA XII; Bali, Indonesia.
18. Thompson MM, Underwood MJ, Sayers RD,
Dookeran KA, Bell PRF. Peripheral tuberculosis
lymphadenop-hathy: review of 67 cases. Br J Surg
1992;79:763-4.
19. Lau SK, Wei WI, Engzell UCG. Efficacy of fine
needle aspiration cytology in the diagnosis of tuber-
culosis cervical lymphadenopathy. J Laryngo Otol
1990;104: 24-7.
Published
2016-10-10
How to Cite
1.
Nilawardhani S, Lubis H, Daulay R, Panggabean G, Hasibuan S. Comparison of clinical aspects and Mantoux test in tuberculosis versus non-tuberculosis superficial lymphadenitis. PI [Internet]. 10Oct.2016 [cited 28Nov.2024];44(2):55-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/737
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Received 2016-09-29
Accepted 2016-09-29
Published 2016-10-10
Accepted 2016-09-29
Published 2016-10-10
