Association between the absence of colostrum feeding and symptoms of intestinal obstruction or neonatal necrotizing enterocolitis
Keywords:
absence of colostrum, symptoms of intestinal obstruction, neonatal necrotizing enterocolitis
Abstract
Objective To assess the relationship between withholding colos-trum and symptoms of intestinal obstruction (SIO) or neonatal ne-
crotizing enterocolitis (NNEC).
Methods This was a longitudinal cohort study in four subdistricts
in West Lombok involving mothers and live newborns. Mothers
were interviewed about prenatal care, delivery process, and prac-
tice of colostrum feedings. Neonates were followed everyday for
28 days by field assistants for signs of intestinal obstruction or
NNEC. We used X 2 test to analyze the association between the
absence of colostrum feeding and the occurence of SIO and stu-
dent t test to compare the average of colostrum feeding between
the SIO and the non-SIO group.
Results 3420 live newborns between 1993-1994 were observed.
1900 mothers gave colostrum while 1520 did not. The incidence of
SIO was 1.8%. There was a significant association between the
absence of colostrum feeding and the occurence of the SIO (RR
1.816; 95%CI 1.08-3.06; p=0.028). No infants with NNEC were
given colostrum.
Conclusion The absence of colostrum feeding is an important
risk factor for the occurence of SIO and NNEC in neonates
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role of effector cells on the intestinal mucosa gastrointes-
tinal host defenses in intractable diarrhea. In: Chronic
diarrhea in children. Nestle Nutrition Workshop Series.
Vol 6. New York: Nestles, Vevey/Raven press; 1984. p.
29-37.
29. Central Bureau Statistic of Indonesia and Macro In-
ternational Inc. Demographic and health in Indonesia
1994. Maryland, USA; 1995. p. 141-50.
fect of breast-feeding on morbidity in rotavirus gastro-
enteritis. Pediatrics 1984; 74:250-3.
2. Levine M, Losonsky G, Herrington D, Kaper J, Tacked C,
Rennels MB, and Morris G. Pediatric diarrhea, the chal-
lenge of prevention. Pediatr Infect Dis J 1986;5:29-43.
3. Yoshioka H, Iseki K, and Fujita K. Development and
differences of intestinal flora in neonatal period in
breastfed and bottle-fed infants. Pediatrics 1983;
72:317-20.
4. Lawrence RA. Breast-feeding. A guide for the medical
profession. 4th ed. Missouri, USA: Mosby-Year book;
1994. p. 95-9.
5. Lebenthal, E. Prolonged small intestinal mucosal in-
jury as a primary cause of intractable diarrhea of in-
fancy. In: Lebenthal, E. Chronic diarrhea in children.
New York: Nestles Vevey/Raven Press; 1984. p. 5-29.
6. Walker AW. Effect of colostrum on the maturation of
intestinal host defense. In: Lebenthal, E. Textbook of
gastroenterology and nutrition in infancy. New York:
Nestle, Vevey/Raven Press; 1981. p. 225-38.
7. Boix-Ochoa J, Cannal J. Maturation on the lower
esophagus. J Pediatr Surg 1976;11:749-56.
8. USAID. The report of ethnographic research in East
Java and West Nusa Tenggara Province; West Nusa
Tenggara: The weaning project; 1989.
9. Wiryo H. The Effect of the use of banana (Musa
paradisiaca) as early solid food feeding and the absence
of colostrum on the incidence of the symptoms of in-
testinal obstruction in neonates. [Dissertation].
Yogyakarta: Gadjah Mada University, Indonesia; 1996.
10. Wiryo H. Prelacteal feeding and its implications on
infant mortality. Proceedings of the Scientific Meeting
of the Coordination Body of Pediatric Gastroenterol-
ogy Indonesia XI; 1989; Jakarta, Indonesia.
11. Dodge JA. Trauma and foreign substance. Pediatric gas-
trointestinal disease pathophysiology, diagnosis, and
management vol. I. 2nd ed. Mosby St. Louis; 1996. p.
528-32.
12. Giles W. Necrotizing enterocolitis in a perinatal cen-
ter. J Pediatr Child Health 1992;28:47-9.
13. Bell MJ, Ternberg JL. Neonatal necrotizing enterocoli-
tis therapeutic decision based upon clinical staging.
Ann Surg 1978;187(pt 1):1-7.
14. Fleiss JD. Statistical methods for rates and proportions.
2nd ed. Wiley; 1982. p. 38-45.
15. Schlesselman J. Case-control studies. Design, conduct,
analysis. 2nd ed. England: Oxford University Press Inc;
1982. p. 145-50.
16. Corner G. dSURVEY user manual. Pearce, Australia:
Helkorn Pty. Ltd; 1989.
17. Dean AG, Dean JA, Burton AH, and Dicker RC.
EpiInfo, version 5, a word processing, database, and
statistics program for epidemiology on microcomputer.
Atlanta, Georgia, USA: Centers for Disease Control;
1990.
18. Wilkinson L. Systat. Evanston Inc: Illinois, USA; 1990.
19. Dixon WJ, Brown MB, Engelman L, Jenrich RI. BMPD.
Statistical software manual vol. 1&2. Berkeley: Uni-
versity of California Press; 1990.
20. Oemijati S, Setiabudy R, Budijanto A. A guideline of
ethics in medical research. Jakarta: Balai Penerbit FKUI;
1987.
21. WHO. International guidelines for ethical review of
epidemiological studies. Geneva: Cioms; 1991.
22. Vaughan VV, McKay RJ, Behrmanm RE. Nelson’s text-
books of pediatrics. ASEAN edition. 11th ed. Tokyo:
WB Saunders Company Philadelphia, IGAKU Shoin;
1979. p. 1102-3.
23. Lebenthal E. Textbook of gastroenterology and nutri-
tion in infancy. New York: Raven Press; 1989. p. 964.
24. Gryboski JD. Suck and swallow in the premature in-
fant. Pediatrics 1969;43:96-102.
25. Avery EM and Tuesch HW. Diseases of the newborn.
5 th ed. Philadelphia: WB Saunders Co; 1984. p. 310-14.
26. Rodgers IM, Davidson DC, Lawrence J, Ardil J,
Buchanan KD. Neonatal secretion of gastrin and glu-
cagon. Arch Dis Child 1974; 49:796-801.
27. Agunod M, Yamaguchi N, Loprez R, Luhby AL, Jerzy
G. Correlative study of hydrochloric acid, pepsin and
intrinsic factor secretion in the newborn and infants.
Am J Dig Dis 1969; 14:400-14.
28. McDermott RM, Befus AD, Bienestock J. The possible
role of effector cells on the intestinal mucosa gastrointes-
tinal host defenses in intractable diarrhea. In: Chronic
diarrhea in children. Nestle Nutrition Workshop Series.
Vol 6. New York: Nestles, Vevey/Raven press; 1984. p.
29-37.
29. Central Bureau Statistic of Indonesia and Macro In-
ternational Inc. Demographic and health in Indonesia
1994. Maryland, USA; 1995. p. 141-50.
Published
2016-10-10
How to Cite
1.
Wiryo H, Hakimi M, Wahab A, Soeparto P. Association between the absence of colostrum feeding and symptoms of intestinal obstruction or neonatal necrotizing enterocolitis. PI [Internet]. 10Oct.2016 [cited 22Nov.2024];44(1):7-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/725
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Received 2016-09-28
Accepted 2016-09-28
Published 2016-10-10
Accepted 2016-09-28
Published 2016-10-10
