Comparison of oxygen saturation measured by pulse oximetry and arterial blood gas analysis in neonates
Keywords:
arterial oxygen saturation, pulse oximetry, arterial blood gas analysis, neonates
Abstract
Background Arterial blood gas is usually beneficial to discern thenature of gas exchange disturbances, the effectiveness of com-
pensation, and is required for adequate management. Although
PaO 2 is the standard measurement of blood oxygenation, oxygen
saturation measured by pulse oximetry (SapO 2 ) is now a custom-
ary noninvasive assessment of blood oxygenation in newborn in-
fants.
Objective To compare oxygen saturation measured by pulse oxi-
metry (SapO 2 ) and arterial blood gas (SaO 2 ), its correlation with
other variables, and to predict arterial partial pressure of oxygen
(PaO 2 ) based on SapO 2 values.
Methods A cross sectional study was conducted on all neonates
admitted to Pediatric Intensive Care Unit (PICU) during February
2001 to May 2002. Neonates were excluded if they had impaired
peripheral perfusion and/or congenital heart defects. Paired t-test
was used to compare SapO 2 with SaO 2 . Correlation between two
quantitative data was performed using Pearson’s correlation. Re-
gression analysis was used to predict PaO 2 based on SapO 2 val-
ues.
Results Thirty neonates were included in this study. The differ-
ence between SaO 2 and SapO 2 was significant . There were sig-
nificant positive correlations between heart rate /pulse rate and
TCO 2 , HCO 3 ; respiratory rate and TCO 2 , HCO 3 , base excess (BE);
core temperature and HCO 3 , BE; surface temperature and pH,
TCO 2, HCO 3, BE; SapO 2 and pH, PaO 2 ; and significant negative
correlation between SapO 2 and PaCO 2 ; the correlations were weak.
The linear regression equation to predict PaO 2 based on SapO 2
values was PaO 2 = -79.828 + 1.912 SapO 2 .
Conclusion Pulse oximetry could not be used in place of arterial
blood gas analysis available for clinical purpose
References
1. Haller M, Kilger E, Briegel J, Forst H, Peter K. Con-
tinuous intra-arterial blood gas and pH monitoring in
critically ill patients with severe respiratory failure: a
prospective, criterion standard study. Crit Care Med
1994;22:580-7.
2. Lister G, Fontan JJP. Pediatric critical care. In: Nelson
WE, Behrman RE, Kliegman RM, Arvin AM, editors.
Nelson textbook of pediatrics. 15 th ed. Philadelphia:
Saunders; 1996. p. 239-45.
3. Durand DJ, Phillips BL. Blood gases: technical aspects
and interpretation. In: Goldsmith JP, Karotkin EH,
editors. Assisted ventilation of the neonate. 3 rd ed.
Philadelphia: Saunders; 1996. p. 257-71.
4. Gomella TC, Cunningham MD, Eyal FG. Neonatol-
ogy: management, procedures, on-call problems, dis-
eases and drugs. 3 rd ed. USA: Appleton & Lange;
1994. p. 43-69, 226-9, 243-4.
5. Burton GG, Hodgkin JE. Respiratory care: a guide
to clinical practice. 2 nd ed. Philadelphia: Lippincott;
1984. Cited from: Kornhauser MS. Blood gas inter-
pretation. In: Spitzer AR, editor. Intensive care of
the fetus and neonate. St. Louis: Mosby; 1996. p.
440-57.
6. Brockway J, Hay WW. Prediction of arterial partial
pressure of oxygen with pulse oxygen saturation mea-
surements. J Pediatr 1998;133:63-6.
7. Fanconi S, Doherty P, Edmonds JF, Barker GA, Bohn
DJ. Pulse oximetry in pediatric intensive care: com-
parison with measured saturations and transcutane-
ous oxygen tension. J Pediatr 1985;107:362-6.
8. Southall DP, Bignall S, Stebbens VA, Alexander JR,
Rivers RPA, Lissauer T. Pulse oximeter and transcu-
taneous arterial oxygen measurements in neonatal
and pediatric intensive care. Arch Dis Child
1987;62:882-8.
9. Russell RIR, Helms PJ. Comparative accuracy of pulse
oximetry and transcutaneous oxygen in assessing arte-
rial saturation in pediatric intensive care. Crit Care
Med 1990;18:725-7.
10. Rajadurai VS, Walker AM, Yu VYH, Oates A. Effect
of fetal haemoglobin on the accuracy of pulse oxim-
etry in preterm infants. J Pediatr Child Health
1992;28:43-6.
11. Bland JM, Altman DG. Statistical methods for as-
sessing agreement between two methods of clini-
cal measurement. Available from: URL: http://
www.sghms.ac.uk/depts/phs/staff/jmb/ba.htm.
tinuous intra-arterial blood gas and pH monitoring in
critically ill patients with severe respiratory failure: a
prospective, criterion standard study. Crit Care Med
1994;22:580-7.
2. Lister G, Fontan JJP. Pediatric critical care. In: Nelson
WE, Behrman RE, Kliegman RM, Arvin AM, editors.
Nelson textbook of pediatrics. 15 th ed. Philadelphia:
Saunders; 1996. p. 239-45.
3. Durand DJ, Phillips BL. Blood gases: technical aspects
and interpretation. In: Goldsmith JP, Karotkin EH,
editors. Assisted ventilation of the neonate. 3 rd ed.
Philadelphia: Saunders; 1996. p. 257-71.
4. Gomella TC, Cunningham MD, Eyal FG. Neonatol-
ogy: management, procedures, on-call problems, dis-
eases and drugs. 3 rd ed. USA: Appleton & Lange;
1994. p. 43-69, 226-9, 243-4.
5. Burton GG, Hodgkin JE. Respiratory care: a guide
to clinical practice. 2 nd ed. Philadelphia: Lippincott;
1984. Cited from: Kornhauser MS. Blood gas inter-
pretation. In: Spitzer AR, editor. Intensive care of
the fetus and neonate. St. Louis: Mosby; 1996. p.
440-57.
6. Brockway J, Hay WW. Prediction of arterial partial
pressure of oxygen with pulse oxygen saturation mea-
surements. J Pediatr 1998;133:63-6.
7. Fanconi S, Doherty P, Edmonds JF, Barker GA, Bohn
DJ. Pulse oximetry in pediatric intensive care: com-
parison with measured saturations and transcutane-
ous oxygen tension. J Pediatr 1985;107:362-6.
8. Southall DP, Bignall S, Stebbens VA, Alexander JR,
Rivers RPA, Lissauer T. Pulse oximeter and transcu-
taneous arterial oxygen measurements in neonatal
and pediatric intensive care. Arch Dis Child
1987;62:882-8.
9. Russell RIR, Helms PJ. Comparative accuracy of pulse
oximetry and transcutaneous oxygen in assessing arte-
rial saturation in pediatric intensive care. Crit Care
Med 1990;18:725-7.
10. Rajadurai VS, Walker AM, Yu VYH, Oates A. Effect
of fetal haemoglobin on the accuracy of pulse oxim-
etry in preterm infants. J Pediatr Child Health
1992;28:43-6.
11. Bland JM, Altman DG. Statistical methods for as-
sessing agreement between two methods of clini-
cal measurement. Available from: URL: http://
www.sghms.ac.uk/depts/phs/staff/jmb/ba.htm.
Published
2016-10-10
How to Cite
1.
Yanda S, Lubis M, Yusroh Y. Comparison of oxygen saturation measured by pulse oximetry and arterial blood gas analysis in neonates. PI [Internet]. 10Oct.2016 [cited 23Dec.2024];43(6):211-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/696
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Received 2016-09-24
Accepted 2016-09-24
Published 2016-10-10
Accepted 2016-09-24
Published 2016-10-10
