Brainstem auditory evoked potentials in children with microcephaly
Keywords:
hearing loss, microcephaly, auditory brainstem pathways
Abstract
Background Hearing loss (HL) is commonly found in childrenwith microcephaly. The aim of this study was to reveal hearing loss
and auditory brainstem pathways disorders in children with micro-
cephaly and other handicaps.
Methods There were 194 children who were referred for hearing
evaluation. Subjects with history of congenital perinatal infection
(TORCH) were excluded. Data were collected from the results of
Brainstem Auditory Evoked Potentials (BAEP) recordings, includ-
ing sex, age, clinical manifestations, latency and interlatency be-
tween waves I, III, V, and the hearing levels of each ear.
Results Moderate to profound HL were found in fourteen ears
(58%) of patients with microcephaly. Moderate to profound HL (28%)
and endocochlear damage (15%) were found in the ears of pa-
tients with microcephaly and delayed speech. Moderate to pro-
found HL (39%) and endocochlear damage (11%) were detected
in the ears of patients with microcephaly and delayed develop-
ment. Moderate to profound HL (21%) and endocochlear damage
(16%) were found in the ears of microcephalic patients with both
delayed speech and delayed development. Moderate to profound
HL (26%) and endocochlear damage (32%) were detected in the
ears of patients with microcephaly and cerebral palsy.
Conclusion This study revealed the importance of early HL de-
tection in microcephalic patients especially those with other handi-
caps such as delayed speech, delayed development, and cere-
bral palsy
References
1. Erenberg S. Automated auditory brainstem response
testing for universal newborn hearing screening.
Otolaryng Clin North Am 1999;32:993–7
2 Picton TW, Taylor MG, Durieux-Smith A. Brainstem au-
ditory evoked potentials in infants and children. In: Aminoff
MJ, editor. Electrodiagnosis in clinical neurology, 4 th ed.
New York: Churchill Livingstone; 1999. p. 485-511
3. DeMyer W. Microcephaly, micrencephaly, megalo-
cephaly and megalencephaly. In: Swiman KE, Ashwal
S, editors. Pediatric neurology: principles & practice.
3 rd ed St Louis: Mosby; 1999. p. 1438-69
4. American Electroencephalographic Society. Guide-
line for clinical evoked potential studies. J Clin
Neurophysiol 1984; 1:3-54
5. Duclaux R, Sevin F, Ferber C, Drai MF, Dubreui C.
Brainstem auditory evoked potentials following men-
ingitis in children. Brain Dev 1993;340-5
6. Rapin I. Hearing impairment. In: Swiman KE, Ashwal
S, editors. Pediatric neurology: principles & practice.
3 rd ed. St Louis: Mosby; 1999. p. 77-95
7. Joint Committee on Infant Hearing: 1994 position
statement. ASHA 1994; 36:38 - 42
8. Leung AKC, Kao CP. Evaluation and management of
the child with speech delayed. Am Fam Phys 1999;
59:282-6
9. Squires N, Aine C, Buchwald J, Norman R, Galbraith
G. Auditory brainstem responses abnormality in se-
verely and profoundly retarded adult. Electrocephalogr
Clin Neurophysiol 1980; 50:172-85
testing for universal newborn hearing screening.
Otolaryng Clin North Am 1999;32:993–7
2 Picton TW, Taylor MG, Durieux-Smith A. Brainstem au-
ditory evoked potentials in infants and children. In: Aminoff
MJ, editor. Electrodiagnosis in clinical neurology, 4 th ed.
New York: Churchill Livingstone; 1999. p. 485-511
3. DeMyer W. Microcephaly, micrencephaly, megalo-
cephaly and megalencephaly. In: Swiman KE, Ashwal
S, editors. Pediatric neurology: principles & practice.
3 rd ed St Louis: Mosby; 1999. p. 1438-69
4. American Electroencephalographic Society. Guide-
line for clinical evoked potential studies. J Clin
Neurophysiol 1984; 1:3-54
5. Duclaux R, Sevin F, Ferber C, Drai MF, Dubreui C.
Brainstem auditory evoked potentials following men-
ingitis in children. Brain Dev 1993;340-5
6. Rapin I. Hearing impairment. In: Swiman KE, Ashwal
S, editors. Pediatric neurology: principles & practice.
3 rd ed. St Louis: Mosby; 1999. p. 77-95
7. Joint Committee on Infant Hearing: 1994 position
statement. ASHA 1994; 36:38 - 42
8. Leung AKC, Kao CP. Evaluation and management of
the child with speech delayed. Am Fam Phys 1999;
59:282-6
9. Squires N, Aine C, Buchwald J, Norman R, Galbraith
G. Auditory brainstem responses abnormality in se-
verely and profoundly retarded adult. Electrocephalogr
Clin Neurophysiol 1980; 50:172-85
Published
2016-09-24
How to Cite
1.
Mangunatmadja I, Widodo D, Pusponegoro H. Brainstem auditory evoked potentials in children with microcephaly. PI [Internet]. 24Sep.2016 [cited 14Nov.2024];43(1):28-0. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/655
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Received 2016-09-22
Accepted 2016-09-22
Published 2016-09-24
Accepted 2016-09-22
Published 2016-09-24
