Association between serum vitamin D level and tuberculosis in children

Main Article Content

Ahmad Zaeni Syafii
Abdurachman Sukadi
Budi Setiabudiawan


Background A possible association between vitamin 0 and
tuberculosis has been described. In adult, vitamin 0 is considered
to have a role in protecting tuberculosis. On the other hand,
tuberculosis infection can decrease serum vitamin 0 level.
Objective To find out the difference between serum vitamin 0
level in children with and without tuberculosis, and to find the
association of serum vitamin 0 level with tuberculosis.
Methods A cross sectional study was conducted in Cibabat Hospital,
Ban dung from July to October 2007. We selected children :S 14
years, diagnosed as tuberculosis, and had positive response after
two month treatment; for control we selected randomly siblings
or neighbors who didn't have tuberculosis. We excluded children
with liver abnormalities and immunocompromized children.
Mann-Whitney test and OR method with 95% confidence interval
was used to analyze the data.
Results Thirty-nine children with tuberculosis (21 boys, 18 girls)
and 39 children without tuberculosis (19 boys, 20 girls) as were
enrolled. Mean serum vitamin 0 level of children with and without
TB were 4 7 (SO 25) pmol/L and 125 (SO 3 7) pmol/L, respectively
(P=O.OOl). All children without tuberculosis had normal vitamin
0 level while of those with tuberculosis, 14 children had normal
level and 25 children were deficient (corrected OR: 139, 95%CI
8 to 238).
Conclusion Serum vitamin 0 level is low in children with

Article Details

How to Cite
Syafii A, Sukadi A, Setiabudiawan B. Association between serum vitamin D level and tuberculosis in children. PI [Internet]. 15Sep.2016 [cited 21Oct.2020];48(6):350-. Available from:
Author Biographies

Ahmad Zaeni Syafii

Department of Child Health, Medical School, Padjadjaran
University, Hasan Sadikin General Hospital, Bandung, Indonesia.

Abdurachman Sukadi

Department of Child Health, Medical School, Padjadjaran
University, Hasan Sadikin General Hospital, Bandung, Indonesia.

Budi Setiabudiawan

Department of Child Health, Medical School, Padjadjaran
University, Hasan Sadikin General Hospital, Bandung, Indonesia.
Received 2016-09-14
Accepted 2016-09-14
Published 2016-09-15


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