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tuberculosis has been described. In adult, vitamin 0 is considered
to have a role in protecting tuberculosis. On the other hand,
tuberculosis infection can decrease serum vitamin 0 level.
Objective To find out the difference between serum vitamin 0
level in children with and without tuberculosis, and to find the
association of serum vitamin 0 level with tuberculosis.
Methods A cross sectional study was conducted in Cibabat Hospital,
Ban dung from July to October 2007. We selected children :S 14
years, diagnosed as tuberculosis, and had positive response after
two month treatment; for control we selected randomly siblings
or neighbors who didn't have tuberculosis. We excluded children
with liver abnormalities and immunocompromized children.
Mann-Whitney test and OR method with 95% confidence interval
was used to analyze the data.
Results Thirty-nine children with tuberculosis (21 boys, 18 girls)
and 39 children without tuberculosis (19 boys, 20 girls) as were
enrolled. Mean serum vitamin 0 level of children with and without
TB were 4 7 (SO 25) pmol/L and 125 (SO 3 7) pmol/L, respectively
(P=O.OOl). All children without tuberculosis had normal vitamin
0 level while of those with tuberculosis, 14 children had normal
level and 25 children were deficient (corrected OR: 139, 95%CI
8 to 238).
Conclusion Serum vitamin 0 level is low in children with
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