Detection of hypoxemia and hyperoxemia by pulse oximetry in neonates and children

  • Sri Murni A. Ritonga
  • Ekawati Lutfia Haksari
  • Purnomo Suryantoro
Keywords: blood gas analysis, pulse oximetry, oxygen saturation, hypoxemia, hyperoxemia, diagnostic test

Abstract

Objective To assess the validity of pulse oximetry for detecting
hypoxemia and hyperoxemia in neonates and children.
Methods This was a diagnostic test study conducted in Neonatal
Intensive Care Unit (NICU). The subjects of the study were
neonates of 0-28 days and children aged one month to 14 years
in Pediatric Intensive Care Unit (PICU) of Sardjito Hospital.
Hypoxemia and hyperoxemia were obtained by using NellcorR
pulse oximetry, at the same time as blood gas analysis was obtained
as a gold standard.
Results There were 240 neonates and 268 children enrolled in
this study. Pulse oximetry test with cut-off point 91% (neonates)
and 90% (children) for detecting hypoxemia had sensitivity of
81% and 80%, specificity of 79% and 95% positive predictive
value of 54% and 82% negative predictive value of93% and 93%
positive likelihood ratio of 3. 79 and 14.20 and negative likelihood
ratio of0.25 and 0.24. Pulse oximetry test with cut-off point 95%
(neonates) and 97% (children) for detecting hyperoxemia had
sensitivity of 7 8% and 81% specificity of 66% and 79%, positive
predictive value of77% and 76% negative predictive value of 66%
and 83% positive likelihood ratio of 2.26 and 3.84 and negative
likelihood ratio of 0.34 and 0.24.
Conclusion Pulse oximetry has a fairly good validity in detecting
hypoxemia in neonates and children and in detecting hyperoxemia
in children to however, it is not good enough to be used to detect
hyperoxemia in neonates.

Author Biographies

Sri Murni A. Ritonga
Department of Child Health, Medical School, University of
Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Ekawati Lutfia Haksari
Department of Child Health, Medical School, University of
Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta, Indonesia.
Purnomo Suryantoro
Department of Child Health, Medical School, University of
Gadjah Mada, Dr. Sardjito Hospital, Yogyakarta, Indonesia.

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Published
2016-09-15
How to Cite
1.
Ritonga SM, Haksari E, Suryantoro P. Detection of hypoxemia and hyperoxemia by pulse oximetry in neonates and children. PI [Internet]. 15Sep.2016 [cited 29Mar.2024];48(6):346-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/627
Received 2016-09-14
Accepted 2016-09-14
Published 2016-09-15