Early neonatal mortality rate and the risk factors in Wangaya hospital

  • Made lndah Nastiti Utami Budha
  • Wayan Retayasa
  • Made Kardana
Keywords: early neonate, mortality rate, risk factors

Abstract

Background The first week of life of a neonate is a critical period.
In Asia, early neonatal mortality rate remains high.
Objective To investigate early neonatal mortality rate and the risk
factors in Wangaya Hospital.
Methods A cross sectional study was carried out retrospectively
on neonates registered at Perinatology Unit, Wangaya Hospital
Denpasar, Bali since January 2006. The study was done from
October to November 2007. Data was obtained from medical
record, analyzed as univariate using chi-square test or Fisher's
exact test and multivariate logistic regression analysis model.
Results Early neonatal mortality rate in Wangaya Hospital was 38.7
per 1000 livebirths. Univariate analyses showed that there were
five significant risk factors of early neonatal death, i.e., respiratory
distress, asphyxia, birth weight less than 2500 grams, sepsis, and
gestational age less than 3 7 weeks. Multivariate analysis showed
that those five variables were significant as risk factors of early
neonatal death i.e., OR (95% confidence interval) for respiratory
distress: 16.8 (3.7 to 76.6)], asphyxia: 13.5 (6.1 to 29.9)], birth
weight <2500 grams: 8.1 (3.3 to 19.9)], sepsis: 7.3 (3.1 to 17.1),
and gestational age <37 weeks: 3.5 (1.6 to 7.8)].
Conclusions Early neonatal mortality rate in Wangaya Hospital
remains high. Respiratory distress, asphyxia, birth weight <2500
gram, sepsis, and gestational age <37 weeks were independent risk
factors of early neonatal death.

Author Biographies

Made lndah Nastiti Utami Budha
Department of Child Health, Medical School, Udayana
University, Sanglah Hospital, Denpasar, Indonesia.
Wayan Retayasa
Department of Child Health, Medical School, Udayana
University, Sanglah Hospital, Denpasar, Indonesia.
Made Kardana
Department of Child Health, Medical School, Udayana
University, Sanglah Hospital, Denpasar, Indonesia.

References

1. Purnomo W Safe Motherhood (Upaya penurunan kematian
ibu dan bayi baru lahir) [cited 2007 October 1]. Available
from: URL: http://www.fkm.unair.ac.id/Kespro
2. Komalasari K. Kematian bayi, tragedi yang terlupakan [cited
2007 October 4]. Available from: URL: http: //www.pikiran-
rakyat.com/cetak/0802/24
3. WHO. Neonatal and perinatal mortality. Country,
regional and global estimates (cited 2007 October 7).
Available from: URL: http: //www.whqlibdoc.who.int/
publications/2006/9241563 206 _eng.
4. Suanti BY. Faktor predisposisi dan sebab kematian perinatal
di ruang perinatologi RSUD Wangaya periode 2002-2004
[thesis]. Denpasar: Universitas Udayana, 2005.
5. Madiyono B. Perkiraan besar sampel. In:Sastroasmoro S,
Ismael S, editors. Dasar-dasar metodologi penelitian klinis.
2nd ed. Jakarta: CV Sagung Seto; 2002. p. 270-1.
6. Sugito, Purwanto A, Ismandari F. Glosarium data dan in-
formasi kesehatan. Pusat data dan informasi Departeman
Kesehatan Republik Indonesia; 2005. p. 1-127.
7. Kardana M. Asfiksia neonatorum. In: Suraatmaja S, editor.
Neonatologi praktis. Denpasar: Bag./SMF Ilmu Kesehatan
Anak; 2006. p. 33-6.
8. Hamid A. Asfiksia neonatorum. In: Suraatmaja S, Soetji-
ningsih, editors. Pedoman Diagnosis dan Terapi Ilmu Kese-
hatan Anak RSUP Sanglah Denpasar. Denpasar: Bag./SMF
Ilmu Kesehatan Anak; 2006. p. 178-9.
9. Fanaroff AA, Fanaroff JM. Clinical examination. In: Donn
SM, Sinha SK, editors. Manual of neonatal respiratory care.
2nd ed. Philadelphia: Mosby Elsevier; 2006. p. 89-97.
10. Gomella TC, Cunningham D, Eyal FG, Zenk KE. Neonatol-
ogy: Management, Procedures, On-Call Problems, Disease,
and Drugs. New York: Lange Medical Books/McGraw-Hill;
2004. p. 434-68.
11. Kardana M. Sepsis neonatorum. In: Suraatmadja S, editor.
Neonatologi praktis. Denpasar: Bag./SMF Ilmu Kesehatan
Anak; 2006. p. 41-7.
12. Hamid A. Sepsis neonatorum. In: Suraatmaja S, Soetjiningsih,
editors. Pedoman Diagnosis dan Terapi Ilmu Kesehatan
Anak RSUP Sanglah Denpasar. Denpasar: Bag./SMF Ilmu
Kesehatan Anak; 2000. p. 180-3.
13. Winkjosastro GH. Ilmu Kebidanan. Jrd ed. Jakarta: Yayasan
Bina Pustaka Sarwono Prawirohardjo; 2002. p. 723-90.
14. Jimmy S, Kemiki AD, Vince JD. Neonatal outcome at
Madilon Hospital, Madang: a 5-year review. PNG Med J
2003;46 Suppl 1-2:8-15.
15. Young PC, Glasgow TS, Li X, Guest-Warnick G, Stoddard
G. Mortality oflate-preterm (near-term) newborns in Utah.
Pediatrics 2007; 119:e659-65.
16. Aurora S, Snyder EY. Perinatal asphyxia. In: Cloherty JP,
Eichenwald EC, Stark AR, editors. Manual neonatal care.
5th ed. Philadelphia: Williams & Wilkins; 2004. p. 536-55.
17. Heller G, Schnell RR, Misselwitz B, Schmidt S. Umbilical
blood pH, Apgar scores, and early neonatal mortality. Z
Geburtshilfe Neonatol2003;207 Suppl3:84-9.
18. Casey BM, Donald D, Leveno KJ. The continuing value of
the Apgar score for the assessment of newborn infants. N
EnglJ Med 2001;344 Suppl7:467-71.
19. Weinberger B, Anwar M, Hegyi T, Hiatt M, Koons A, Paneth
N. Antecedents and neonatal consequences of low Apgar
scores in pre term newborns. Arch Pediatr Adolesc Med 2000;
154:294-300.
20. Zupancic JAF. Neural tube defect. In: Cloherty JP, Eichenwald
EC, Stark AR, editors. Manual neonatal care. 5th ed. Phila-
delphia: Lippincott Williams@ Wilkins; 2004. p. 555-63.
21. Puopolo KM. Bacterial and fungal infections. In: Cloherty JP,
Eichenwald EC, Stark AR, editors. Manual neonatal care.
5th ed. Philadelphia: Lippincott Williams @ Wilkins; 2004.
p. 287-312.
22. Lawn JE, Wilczynska-Ketende K, Cousens SN. Estimating
the causes of 4 million neonatal deaths in the year 2000.
International Journal of Epidemiology 2006;35: 706-18.
23. Chen XK, Wen SW, Fleming N, Demissie K, Rhoads
GG, Walker M. Teenage pregnancy and adverse birth
outcomes: a large population based retrospective
cohort study. International Journal of Epidemiology
2007 ;36:368-73.
24. Joseph KS, Allen AC, Dodds L, Turner LA, Scott H, Liston R.
The perinatal effects of delayed childbearing. Obstet Gynecol
2005; 105:1410-8.
25. Wu Z, Viisainen K, Wang Y, Hemminki E. Perinatal
mortality in rural China: retrospevtive cohort study. BMJ
2003;327: 1319-22.
26. Aliyu MH, Salihu HM, Keith LG, Ehiri JE, Islam A, Jolly PE.
High prity and fetal morbidity outcomes. Obstet Gynecol
2005; 105:1045-51.
Published
2016-09-15
How to Cite
1.
Budha M, Retayasa W, Kardana M. Early neonatal mortality rate and the risk factors in Wangaya hospital. PI [Internet]. 15Sep.2016 [cited 23Dec.2024];48(5):306-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/611
Received 2016-09-12
Accepted 2016-09-12
Published 2016-09-15