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association between iron status and children's behavior yet it is
Objective To investigate whether iron therapy has an effect on
the behavior of children with iron deficiency anemia (IDA).
Method A randomized placebo-controlled clinical trial was
conducted in Labuhan Batu on November 2006-April2007. IDA
was defined as Hb < 12 g/dl, MCHC< 31%, ROW index > 220
and Mentzer index> 13. Elementary school children (6-12 years
old) with IDA were randomly assigned to the treatment group
with a daily therapy of 6 mg iron/kg/day or placebo group for three months. The subjects' behavior was evaluated with child behavior check list (CBCL) before and six months after intervention.
Results After six months, 110 subjects completed the therapy.
Scores of CBCL in iron group after intervention were internalizing
42.64 (SO 9.95), externalizing 37.13 (SO 9.04) & total score 38.24 (SO 10.20). There was significant decreased on externalizing and total problems score in the treatment group after intervention (P< 0.05). However, there was no significant difference on scores between groups.
Conclusion Iron therapy had significantly decrease CBCL score
on externalizing and total problems in the treatment group,
however there was no significant difference on scores if compared
with placebo group.
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