The association between onset, frequency, duration of seizure and IQ level in epileptic children

Main Article Content

Yulia Yulia
Sjarif Hidayat Effendi
Budi Setiabudiawan

Abstract

Background Epilepsy is a common neurological disorder found in
all races and age groups. Epilepsy becomes a serious problem when occurs during the child's critical development period. It is known that onset, frequency, and duration of seizures are associated with IQ level. Therefore, intelligent assessment is important to determine prognostic and holistic management.
Objective To determine the association between onset, frequency, duration of seizure and IQ level in epileptic children.
Methods This cross sectional study was carried out at the
Department of Child Health, Hasan Sadikin Hospital, Bandung,
Indonesia from October to December 2007. The subjects were
epileptic children aged 4-16 years old being treated with valproic
acid. Statistic analysis was done using logistic regression analysis, OR and RR, with 95% confidence interval.
Results There were 90 subjects with epilepsy (46 males). Twenty
subjects (22%) showed onset of seizures at < 18 months old; these subjects had 3.08 higher risk for having a low IQ level (score <90) compared to those with seizure onset at~ 18 months old (P=0.003). Sixty subjects (67%) had a seizure frequency of> 10 times annually; they had 1.68 higher risk of having a low IQ
compared to those with seizure frequency< 10 times (P=0.430).
Seven subjects (28.0%) had seizures of> 10 minutes; they had 1.17 higher risk of having a low IQ compared to those with seizures of < 10 minutes (P=0.706).
Conclusion Onset of seizures at < 18 months old is significantly
associated with low IQ level, while frequency and duration
of seizure have no significant association with lower IQ level.

Article Details

How to Cite
1.
Yulia Y, Effendi S, Setiabudiawan B. The association between onset, frequency, duration of seizure and IQ level in epileptic children. PI [Internet]. 1Jul.2009 [cited 16Oct.2019];49(3):177-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/548
Section
Articles
Author Biographies

Yulia Yulia

Department of Child Health, Medical School, Padjadjaran
University, Hasan Sadikin General Hospital, Bandung, Indonesia.

Sjarif Hidayat Effendi

Department of Child Health, Medical School, Padjadjaran
University, Hasan Sadikin General Hospital, Bandung, Indonesia.

Budi Setiabudiawan

Department of Child Health, Medical School, Padjadjaran
University, Hasan Sadikin General Hospital, Bandung, Indonesia.
Received 2016-09-10
Accepted 2016-09-10
Published 2009-07-01

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