Percentage birth weight loss and hyperbilirubinemia during the first week of life in term newborns
Keywords:
birth weight loss percentage, hyperbilirubinemia, term newborn
Abstract
Background Hyperbilirubinemia is the most common problem interm newborns during the first week of life. Hyperbilirubinemia
in term newborns without other risk factors is usually caused
by dehydration and reduced calorie intake that is marked by
excessive weight loss.
Objective To determine the relationship between percentage birth
weight loss and hyperbilirubinemia during the first week of life
in term newborns.
Methods A cross sectional study was conducted at the Department
of Child Health, Medical School, Udayana University, Sanglah
Hospital, Denpasar, Indonesia. The weight of term newborns
was measured on the first, third, and seventh day after birth.
In addition, a complete blood count, reticulocyte count, and
peripheral blood smear, were carried out on the first day. Serum
bilirubin level was measured on the first, third, and seventh day.
Clinical signs, jaundice, type and frequency of intake, and time
of meconium transit were followed during the stay in hospital.
Linear regression, correlation, and logistic regression analysis were
performed to determine variables related to hyperbilirubinemia.
Results 68 newborns were enrolled in this study, with 7 developed
hyperbilirubinemia by the third day. There was a significant
(P<0.001) but weak to moderate correlation (r = 0.39)
between percentage birth weight loss and total serum bilirubin
concentration on the third day. Logistic regression analysis
showed that percentage birth weight loss on the third day was
significantly related to hyperbilirubinemia [OR 38.18 (95% CI
2.29 to 637.61), P=0.011].
Conclusion Percentage birth weight loss is related to hyperbilirubinemia
in term newborn during the first week of life.
References
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Gastroenterol Nutr. 1990;10:82-6.
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HA, Verkade HJ. Neonatal jaundice and stool production
in breast- or formula-fed term infants. Eur J Pediatr.
2008;167:501-7.
26. Yamauchi Y, Yamanouchi I. Breastfeeding frequency during
the first 24 hours after birth in full-term neonates. Pediatrics
1990;86:171-5.
really favoring early neonatal jaundice? Pediatrics.
2001; 107 :e41-5.
2. Klein A. Teaching files: management of hyperbilirubinemia in
the healthy full-term infant [cited 2004 May 24'h]. Available
from: URL: http://www.neonatology.org/biblio/bibd.html.
3. AmericanAcademyofPediatrics (AAP). Practice parameter:
management of hyperbilirubinemia in the healthy term
newborn. Pediatrics. 1994;94:558-65.
4. Maisels MJ, Gifford K, Antle CE, Leib GR. Jaundice in the
healthy newborn infant: a new approach to an old problem.
Pediatrics. 1988;81:505-11.
5. Uhudiah U, Oktavia D. Pemberian terapi sinar berdasarkan
penilaian klinis pada neonatus dengan hiperbilirubinemia.
Proceeding of the National Congress and International
Symposium of Perinasia VIII; 2003 October 5-8; Medan,
Indonesia. Jakarta: Perinasia, 2003.
6. Surjono A. Air susu ibu, penurunan berat badan dan
hiperbilirubinemia pada bayi baru lahir dalam minggu
pertama. Berkala Ilmu Kedokteran. 1993;25:41-7.
7. Alpay F, Sarici SU, Tosuncuk HD, Serdar MA, Inane N,
Gokcay E. The value of first-days bilirubin measurement in
predicting the development of significant hyperbilirubinemia
in healthy term newborns. Pediatrics. 2000; 1 06:e 16.
8. Surjono A. Manajemen hiperbilirubinemia pada bayi baru
lahir. Proceeding of the Oda-Day Seminar of Management
oflcterus in neonatus; 2003 May 24; Yogyakarta, Indonesia.
Yogyakarta: FKUGM, 2003.
9. Bhutani VK, Johnson L, Sivieri EM. Predictive ability of a
predischarge hour-specific serum bilirubin for subsequent
significant hyperbilirubinemia in healthy-term and near-term
newborns. Pediatrics. 1999; 103:6-14.
10. Gomella TL, Cunningham MD, Eyal FG. Hyperbilirubinemia.
In: Gomella TL, Cunningham MD, Eyal FG, editors.
Neonatology: management, procedures, on-call problems,
diseases, drugs. 5th ed. USA: Me Graw-Hill Companies, 2004;
p. 381-95.
11. Triasih R, Haksari EL, Surjono A Kadar bilirubin 24 jam
pertama sebagai faktor prediksi hiperbilirubinemia pada
bayi cukup bulan yang sehat. Berkala Ilmu Kedokteran.
2002;34: 141-8.
12. Dennery PA, Seidman DS, Stevenson DK. Neonatal
hyperbilirubinemia. N EnglJ Med. 2001;344:581-90.
13. Gourley GR. Breastfeeding, diet, and neonatal hyperbilirubinemia.
NeoReviews. 2000; l:e25.
14. Wright CM, Parkinson KN. Postnatal weight loss in term
infants: what is "normal" and do growth charts allow for it?
Arch Dis Child Fetal Neonatal Ed. 2004; 89:F254-7.
15. Maisels MJ. Neonatal jaundice. Pediatr in rev. 2006; 27:443-
53.
16. Almeida MF, Draque CM. Neonatal jaundice and breastfeeding.
NeoReviews. 2007 ;8:e282-8.
17. Ding G, Zhang S, Yao D, Na Q, Wang H, Li L, et al. An
epidemiological survey on neonatal jaundice in China. Chin
MedJ Engl. 2001; 114:344-7.
18. Keating JP. Jaundice. In: Walker WA, Durie PR, HamiltonJR,
Walker-SmithJA, Watkins JB, editors. Pediatric gastrointestinal
disease: patophysiology, diagnosis, management. 3rd ed.
Canada: BC Decker Inc, 2000; p. 226-31.
19. Chandran L, Gelfer P. Breastfeeding: the essential principles.
Pediatr in rev.2006;27:409-16.
20. Sarici SU, Serdar MA, Korkmaz A, Erdem G, Oran 0,
Tekinalp G, et al. Incidence, course, and prediction of
hyperbilirubinemia in near-term and term newborns.
Pediatrics 2004; 113:775-80.
21. Dewey KG, Nommsen-Rivers LA, Heinig MJ, Cohen RJ.
Risk factors for suboptimal infant breastfeeding behaviour,
delayed onset of lactation, and excess neonatal weight loss.
Pediatrics. 2003; 112:607-19.
22. Niestijl AL, Sauer PJ. Breastfeeding during the first few days
after birth: sometimes insufficient. Ned Tijdschr Geneeskd.
2003; 147:2405-7.
23. GaleR, Seidman DS, Dollberg S, Stevenson DK. Epidemiology
of neonatal jaundice in the Jerusalem population. J Pediatr
Gastroenterol Nutr. 1990;10:82-6.
24. Salariya EM, Robertson CM. Relationship between baby
feeding types and patterns, gut transit time of meconium and
the incidence of neonatal jaundice. Midwifery. 1993;9:235-
42.
25. Buiter HD, Dijkstra SS, Elferink RFM, Bijster P, Woltil
HA, Verkade HJ. Neonatal jaundice and stool production
in breast- or formula-fed term infants. Eur J Pediatr.
2008;167:501-7.
26. Yamauchi Y, Yamanouchi I. Breastfeeding frequency during
the first 24 hours after birth in full-term neonates. Pediatrics
1990;86:171-5.
Published
2009-07-01
How to Cite
1.
Indriyani SAK, Retayasa IW, Surjono A, Suryantoro P. Percentage birth weight loss and hyperbilirubinemia during the first week of life in term newborns. PI [Internet]. 1Jul.2009 [cited 13Nov.2024];49(3):149-54. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/543
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Received 2016-09-10
Accepted 2016-09-10
Published 2009-07-01
Accepted 2016-09-10
Published 2009-07-01
