Main Article Content
Background Currently the age at onset of menarche is earlier
than in the past. Nutritional status has an important role in
the onset of menarche. Past studies have shO\vn an association
between body mass index (BMI) in young girls and earlier onset
Objective To assess an association between BMI and age at onset
Methods This crosssectional study was conducted in young
girls aged 10 to 15 years from Immanuel Elementary and Junior
High School, Medan in June 2010. We used purposive sampling
to recruit subjects. After subjects underwent height and weight
measurements, we calculated their BMIs. The association between
BMI and initial age of menarche was assessed by Chi square test
(P<O.05 v.ith a 95% confidence interval).
Results Eightyfive subjects participated in this study. There were
44 subjects in the 5th85th percentile ofBMI (nonnoweight), 19
subjects with 85th95th percentile of BMI (overweight) and 12
subjects in the> 95th percentile ofBMI (obese). All obese subjects
had an earlier onset of menarche at ages 1O 11 years, compared
to that of nonobese subjects (P=O.OOOl).
Conclusion Young girls v.ith BMI > 95th percentile had an
earlier age at onset of menarche than young girls v.ith lower BMls.
[Paediatr lndanes. 2012,52:309-12].
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Tridjaja B, Pulungan AB, editors. Buku ajar endokrinologi
anak. 1 Hed. Jakarta: UKK EndokrinologiAnak dan Remaja
IDA!; 2010. p. 85 ·121.
2. Ozdemir F, Nazik E, Pasinlioglu T. Determination of the
motherly reactions to adolescents' experience of menarche.
J Pediatr Adolese Gyneeol. 2010;23,153·7.
3. Berenjy S, Hanachi P. Relation of obesity and menarche
age among adolescent students. J Fam Reprod Health.
4. HermanGiddens ME, Slora EJ, Wasserman RC, Bourdony
CJ, Bhapkar MV, Koch GG, et al. Secondary sexual
characteristics and menses in young girls seen in office
practice: a study from Pediatric Research in Office Settings
ne twork. Pediatrics. 1997;99:505-12.
5. Dattani MT, Hindmarsh PC. Normal and abnormal puberty.
In: Brook CGD, Clayton PE, Bro\Vll RS, editors. Clinical
pediatric endocrinology.5 thed.O xford: Blackwell Publishing;
1995. p. 183-20.
6. Styne DM. Normal growth and pubertal development. In
: Sanfilippo JS, Muram D, Dewhurst J, Lee PA, editors.
Pediatric and adolescent gynecology.2 nd edition.P hiladelphia
Toronto: WB Saunders Company, 2002. p. 2345-55.
7. Ekerbicer HC, Celik M, Kiran H, Kiran G. Age at menarche
in Turkish adolescents in Kahramanmaras, Eastern
Mediterranian region of Turkey. Eur J Contracept Reprod
Health Care. 2007;12,289-93.
8. Golub MS, Collman Gw, Foster PMD, Kimmel CA, De Meyts
ER, Reiter EO, et al. Public health implications of altered
puberty timing.P ediatrics.2 008; 121,S218-30.
9. Euling SY, HermanGidden ME, Lee PA, Selevan SG, Juul
A, Sorensen TI, et al. Examination of US pubertytiming
data from 1940 to 1994 for secular trends: panel findings.
10. Ersoy B, Balkan C, Gunay T, Egemen A. The factors affecting
the relation between the menarcheal age of mother and
daughter. Child Care Health Dev. 2005;31;303-8.
11. Anderson SE, Dallal GE, Must A. Relative weight and
race influence average age at menarche: results from two
nationally representative surveys of US girls studied 25 years
apart. Pediatrics. 2003; 111,844-50.
12. Freedman DS, Khan LK, Serdula MK, Dietz WH, Srinivasan
SR, Berenson GS. Relation of age at menarche to race, time
period, and anthropometric dimensions: the Bogalusa heart
study. Pediatrics. 2002;110:e43.
13. Wyshak G, Frisch RE. Evidence for a secular trend in age of
menarche. N Eng j Med. 1982;306,1033-5.
14. Gam SM, Haskell jA. Fat and growth duting childhood.
15. Kaplowitz PB, Slora EJ, Wasserman RC, Pedlow SE,
HermanGiddens ME. Earlier onset of puberty in girls:
relation to increased body mass index and race. Pediatrics.
16. Rosenfield RL, Lipton RB, Drum ML. Thelarche, pubarche,
and menarche attainment in children with normal and
elevated body mass index.P ediatrics.2 009; 123:848.
17. JM Tanner. Growth of adolescents. Oxford:Blackwell
Scientific Publications; 1962. p. 2326.
18. Frisch RE, Revelle R. Height and weight at menarche and a
hypothesis of menarche. Arch Dis Child. 1971;46,695-701.
19. Musaiger AO. Height, weight, and menarcheal age of
adolescent girls in Oman. Ann Hum Biol. 1991;18:71A.
20. Chang SH, T ,eng Sj, Cheng jY, Chie WC.H eight and weight
change across menarche of schoolgirls with early menarche.
Arch Pediatr Adolesc Med. 2000; 154,880-4.
21. Bau AM, Ernert A, Schenk L, Wiegand S, Martus P, Gruters
A, et al.I s there a further acceleration in the age at onset of
menarche? A crosssectional study in 1840 school children
focusing on age and bodyweight at the onset of menarche.
Euro j Endoctino!. 2009; 160,107-13.
22. De La Punte ML, Canela J, Alvarez J, Salleras L, Vincens
Calvet E. A crosssectional growth study in 954 of the child
and adolescent population of Catalonia (Spain). Ann Hum
23. Wu T, Mendola P, Buck GM. Ethnic differences in the
presence of secondary sex characteristics and menarche
among US girls: the T hird National Health and Nutrition
Examination Survey, 1988 1994. Pediatrics. 2002; 110:
24. Troiano RP, Flegal KM, Kuczmarski RJ, Campbell SM,
Johnson CL. Overweight prevalence and trends for
children and adolescents: the national health and nutrition
examination surveys, 1963 to 1991. Arch Pediatr Adolesc
25. Yalcin SS, Kinik E. The impact of the sexual maturation
stage of body mass index in adolescent girls.T urk J Pediatr.
26. Garibaldi L. Physiology of puberty. In: Behrman RE,
Kliegman RM, Jenson HB, editors. Nelson textbook of
pediatrics. 18th ed. Philadelphia: Saunders Elsevier; 2008.
27. Stavrou I, Zois C, Chatzikyriakidou A, Georgiou I, Tsatsoulis
A. Combined estrogen receptor a and estrogen receptor jJ
genotypes influence the age of menarche. Hum Reprod.
28. Stavrou I, Zois C, Ioannidis JPA, Tsatsoulis A. Association
of polymorphism of the oestrogen receptor a gene Mth the
age of menarche. Hum Reprod. 2002;17:11015.
29. Burt SA, McGue M, DeMarte JA, Krueger RF, Iacono WG.
Timing of menarche and the origins of conduct disorder.A rch
Gen Psychiatry. 2006;63,890-6.