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increased rapidly and remains a social as well as an economic
problem for the patients on account of its chronic nature. In order
to decrease the atopic diseases, especially atopic dermatitis in
infants, nursing mothers should avoid allergenic foods as a
preventive sensitization. Egg allergy is the most common cause of
food allergy, and is closely related to atopic dermatitis in children.
Objective To determine whether egg avoidance diet by nursing
mothers could decrease the incidence of atopic dermatitis in
Method We conducted a parallel randomized-controlled trial.
Seventy-nine subjects eligible for the study were divided into two
groups: egg avoidance and non-egg avoidance group. Block
randomization is used for random allocation. Intervention started
since mothers had had delivery until their children were 4 months
old. The primary outcomes were clinical atopic dermatitis.
Result Atopic dermatitis incidence in maternal egg avoidance
group was significantly lower than non-avoidance group. Non-
avoidance, family history of asthma, and maternal allergy are the
factors significantly influencing atopic dermatitis incidence (OR
6.17; OR 4.73; OR 0.14), respectively.
Conclusion Egg avoidance by nursing mothers could decrease the
incidence of atopic dermatitis in infants. Non-egg avoidance and
asthma in the families are factors significantly inducing the incidence
of atopic dermatitis.
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