Main Article Content
Background Iodine deficiency disorders (lDD) are a significant
public health problem globally. Iodine deficiency may cause
subclinical hypothyroidism during pregnancy and early infancy.
Neonatal thyroid screening of serum thyroidstimulating hormone
(TSH) to detect hypothyroidism may also be used to determine
the prevalence of IDD in a population. Previous studies reported
mild ID D status in different parts of Indonesia.
Objective To evaluate the iodine status of neonates born in
Mitra K eluarga Surabaya Hospital (MKSH) by TSH screening
over a 6year period.
Methods T his is a crosssectional and hospitalbased study
conducted in MKSH from January 2005 to December 2010. Of
the 5,619 infants born in MKSH during the study period, 3,349
(59.6%) healthy infants took part in this study. Blood specimens
for TSH measurement were collected from subjects 2 to 6 days
after birth, and sent to a reference laboraratory for evaluation.
Using the neonatal TSH values, the iodine deficiency level of
the group was determined according to the WHO/UNICEF/
International Council for the Control of IDD criteria.
Results A total of 3,349 newborn babies underwent neonatal
TSH screening in MKSH. Subjects' mean TSH concentration
was 5.14 mIU!L. A TSH concentration> SmIU!L was found in
1270 (37.9%) subjects, 166 (27.6%) in 2005, 252 (44.0%) in 2006,
331 (47.1 %) in 2007, 356 (57.7%) in 2008, 114 (20.7%) in 2009
and 51 (16.8%) in 2010. On the basis of the WHO/UNICEF/
International Council for the Control of Iodine Deficiency
Disorder criteria, this frequency corresponded to a moderate level
of IDD. Twentytwo neonates had TSH > 20 mIU!L from which
2 infants were confirmed positive for hypothyroidism.
Conclusion A 6year study of 3,349 newborns screened for TSH
revealed that 37.9% of subjects had TSH concentration of more
than SmIU!L. This frequency indicates a moderate level of IDD
in the study population. [Paediatr Indones. 2012;52:289,93].
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