Association between C-reactive protein levels and physical fitness in 7 to 9 year old children at poor elementary schools in Surakarta, Indonesia

  • Lilisianawati Lilisianawati
  • Endang Dewi Lestari
  • Diana Mayasari Hadianto
  • Maria Galuh Kamenyangan Sari
  • Leilani Lestarina
  • Harsono Salimo
Keywords: children, C-reactive protein, physical fitness

Abstract

Background  Data  regarding inflammatory factors  in  children are
not  so  well developed  as  in adults. Higher levels  of  physical fitness
may be helpful in modifying the low-grade inflammatory state  that
is  indexed  by  C-reactive protein (CRP) levels.
Objective  To  evaluate the association  of  physical fitness with  CRP
levels in children  and  to identify the possible related factors.
Methods  This  cross-sectional study was  conducted  at  poor
elementary schools in Surakarta, Indonesia using a group  of  217
underweight children aged from 7 to 9 years old. Physical fitness
was assessed using a modified Harvard Step Test.  CRP  levels were
measured using a high-sensitivity  assay.  The  association between
physical fitness and  CRP  level was assessed using linear regression
analysis. Multivariate analyses were used to adjust covariates,
and statistical analyses were performed using SPSS for Windows
software version 15.0.
Results  Subjects were 48% female  and  52% male, and eleven
children (5%) had a  CRP  level  >  5 mg/L. Mean fitness level  and
CRP  level did not differ  by  age and gender. Fitness level was not
inversely correlated with  CRP  (r=0.10,  P=0.14).  Physical fitness
was significantly correlated with BMI  (r=0.14;  P=0.04),  physical
activity  [0R=3.3  (95% CI  1.7  to 6.4)], and fat intake  [0R=0.5
(95%  CI  0.2 to 0.9) ].
Conclusion  These findings indicate  that  physical fitness  is  not
inversely correlated to  CRP  levels in children. However, our
study reveased  an  association between high fat intake and low
physical fitness as well  as  a significant association  between
high physical activiry and physical fitness.

Author Biographies

Lilisianawati Lilisianawati
Department  of  Child Health, Medical School, Sebelas Maret
University, Surakarta, Indonesia.
Endang Dewi Lestari
Department  of  Child Health, Medical School, Sebelas Maret
University, Surakarta, Indonesia.
Diana Mayasari Hadianto
Department  of  Child Health, Medical School, Sebelas Maret
University, Surakarta, Indonesia.
Maria Galuh Kamenyangan Sari
Department  of  Child Health, Medical School, Sebelas Maret
University, Surakarta, Indonesia.
Leilani Lestarina
Department  of  Child Health, Medical School, Sebelas Maret
University, Surakarta, Indonesia.
Harsono Salimo
Department  of  Child Health, Medical School, Sebelas Maret
University, Surakarta, Indonesia.

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Published
2009-04-30
How to Cite
1.
Lilisianawati L, Lestari E, Hadianto D, Sari M, Lestarina L, Salimo H. Association between C-reactive protein levels and physical fitness in 7 to 9 year old children at poor elementary schools in Surakarta, Indonesia. PI [Internet]. 30Apr.2009 [cited 13Nov.2024];49(2):75-1. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/460
Section
Articles
Received 2016-09-05
Accepted 2016-09-05
Published 2009-04-30