Efficacy of synbiotic and probiotic treatments on acute watery diarrhea in children

  • Ani Isti Rokhmawati Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta
  • Wahyu Damayanti Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta
  • Madarina Julia Department of Child Health, Gadjah Mada University Medical School/Dr. Sardjito Hospital, Yogyakarta
DOI: https://doi.org/10.14238/pi52.4.2012.209-12
Keywords: acute watery diarrhea, synbiotic, probiotic

Abstract

Background In developing countries, acute watery diarrhea is
a common cause of morbidity and mortality in children. Giving
synbiotics or probiotics may decrease the severity of diarrhea.
Objective To compare the efficacy of synbiotics and probiotics
in decreasing the frequency of diarrhea, shortening the duration,
and increasing patient body weight.
Methods This was a doubleô€€·blind, randomized clinical trial to
compare the effects of synbiotic vs probiotic treatment in children
aged 6ô€€·59 months v.ith acute watery diarrhea. This study was
performed from October to December 2010 in two hospitals in
Central Java. Subjects received either synbiotics or probiotics
tv.ice daily for five days. The measured outcomes were duration
of diarrhea, daily frequency of diarrhea, and increase in body
weight.
Results There was no significant difference in the mean duration
of the diarrhea in the synbiotic and probiotic groups, 3.92 days
(SD 0.79) vs 3.80 days (SD 0.82) ,(P􀀸0.35), respectively. Nor did
we observe a significant difference in the mean increase in body
weight in the synbiotic and probiotic groups, 150 g (SD 49.7) vs
160 g (SD 48.9), (P􀀸 0.67), respectively.
Conclusion We observed no significant differences in efficacy of
synbiotic and probiotic treatment for management of acute watery
diarrhea. [Paediatr Indones. 2012;52:209,12].

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Published
2012-08-31
How to Cite
1.
Rokhmawati A, Damayanti W, Julia M. Efficacy of synbiotic and probiotic treatments on acute watery diarrhea in children. PI [Internet]. 31Aug.2012 [cited 24Nov.2024];52(4):209-2. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/398
Issue
Vol 52 No 4 (2012): July 2012
Section
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Received 2016-08-31
Accepted 2016-08-31
Published 2012-08-31