Comparison of 25-hydroxyvitamin D levels in exclusively and non-exclusively breastfed infants

Analysa Margaretha Bogar; Helena Anneke Tangkilisan; Hesti Lestari

doi:10.14238/pi52.3.2012.157-60

Analysa Margaretha Bogar Department of Child Health, Sam Ratulangi University Medical School, Manado
Helena Anneke Tangkilisan Department of Child Health, Sam Ratulangi University Medical School, Manado
Hesti Lestari Department of Child Health, Sam Ratulangi University Medical School, Manado

DOI: https://doi.org/10.14238/pi52.3.2012.157-60

Keywords: vitamin D, deficiency, exclusive breastfeeding

Abstract

Background Vitamin D is an essential nutrient for the
prevention of rickets. Human milk typically contains a vitamin
D concentration of 25 lUlL or less. Breastfed infants are at risk
of vitamin D deficiency. Previous studies conducted in countries
with four seasons have reported that risk factors associated with
vitamin D deficiency influence the vitamin D status in exclusively
breastfed infants.
Objective To compare the levels of 25-hydroxyvitamin D
(25 (OH)D) in exclusively and non-exclusively breastfed in-
fants.
Methods This cross-sectional study was conducted in Singkil
District, Manado from February to May 2011. Of 48 Posyandu
(Integrated Health Center), 4 were chosen to be the sources
of subjects for this study. Subjects were collected consecutively
among infants aged 6-7 months. The resulting exclusively and
non-exclusively breastfed groups had 36 infants each.
Results The mean 25 (OH)D level in the exclusively breastfed
group was 61.75 nmoliL (95% CI 58.02 to 65.48) and in the nonexclusively
breastfed group was 85.09 nmollL (95% CI 79.49 to
90.68). The difference in 25 (OH)D levels in the two groups was
statistically significant. However, 25 (OH)D levels of both groups
were Mthin the normal range.
Conclusion The 25 (OH)D level was significantly lower in ex-
clusively breastfed infants compared to that in non-exclusively
breastfed infants, but both levels were still in the normal range.
[Paediatr rndones. 2012;52:157-60].

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