Factors affecting mortality of neonatal sepsis in Moewardi Hospital, Surakarta
Keywords:
neonatal sepsis, low birth weight, bacterial infection
Abstract
Background Mortality of neonatal sepsis is still a significantproblem. It might be affected by many factors.
Objective The purpose of this study was to determine factors
which affect mortality of neonatal sepsis at neonatal ward of
Moewardi Hospital, Surakarta.
Methods Data of neonatal sepsis was obtained from medical
records at the neonatal ward of Moewardi Hospital from December
2004 to November 2005. We recorded data from 97 neonatal
sepsis consisted of 46 male and 52 female babies. Statistical
analysis had been performed using univariate Chi-square and
multivariate multiple logistic regression analysis.
Results Overall neonatal sepsis mortality was about 40%. There
were no significant difference in factors associated with mortality
of neonatal sepsis such as gender (OR=0.44; 95% CI 0.19;1.014),
referral patients (OR=1.61; 95% CI 0.195;.014), and bacterial
growth culture (OR=1.96; 95% CI 0.856;4.44), except for birth
weight which affected mortality (OR=6.29; 95% CI 2.57;15.42).
Conclusion Birth weight affects mortality of neonatal sepsis in
Moewardi Hospital. Patients with positive bacterial growth culture
has two times higher risk of death, however, it is not statistically
significant.
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in the neonate. Pediatr Clin North Am 2004;51:939.
2. Aminullah A. Masalah terkini sepsis neonatorum. In: Hegar
B, Trihono P, Ifran EB, editors. Update in neonatal infection.
Naskah lengkap pendidikan berkelanjutan Ilmu Kesehatan
Anak FKUI XLVIII. Jakarta: Departemen Ilmu Kesehatan
Anak FKUI; 2005. p. 1-15.
3. Klein JO. Bacterial sepsis and meningitis. In: Remington JS,
Klein JO, editors. Infection diseases of the fetus and new-
born infant. Philadelphia: PA. WB Saunders; 2001. p. 944.
4. Jarvis WR. Epidemiology of nosocomial infection in pediat-
ric patients. Pediatr Infect Dis J 1987;6:344-51.
5. Stoll BJ, Hansen N, Fanaroff AA, Wright LL, Carlo WA,
Ehrenkranz EA, et al. Late-onset sepsis in very low birth
weight neonates: The experience of the NICHD neonatal
research network. Pediatrics 2002;110:285-91.
6. Tseng YC, Chiu YC, Wang JH, Lin HC, Lin HC, Su BH, et
al. Nosocomial bloodstream infection in a neonatal inten-
sive care unit of a medical center: A three-year review. J
Microbiol Immunol Infect 2002;35:168-72.
7. Hafidh Y, Martuti S, Sunyataningkamto. Pola kuman,
sensitivitas antibiotika, dan risiko kematian bayi sepsis di RS
Dr. Moewardi Surakarta. Sari Pediatr. In press; 2006.
8. Eicher DJ, Annibale DJ. Neonatal sepsis: Evaluation and
management. J S C Med Assoc 2002;98:102-7.
9. Bellig LL, Ohning BL. Neonatal sepsis. Available from: url:
http//www.emedicine.com/ped/topic2630.htm.
10. Bizzarro MJ, Raskin C, Baltimore RS, Gallagher PG. Sev-
enty-five years of neonatal sepsis at Yale; 1928-2003. Pediat-
rics 2005;116:595-602.
11. Bang AT, Paul VK, Reddy HM, Baitule SB. Why do neo-
nates die in rural Gadchiroli, India? (Part I): Primary causes
of death assigned by neonatologist based on prospectively
observed records. J Perinatol 2005;25:S29-34.
12. Sepsis neonatal. Standard pelayanan medik divisi Perinatologi
FKUI/RSCM 2004.
13. Aminullah A. Diagnosis dan tatalaksana sepsis pada bayi baru
lahir. In: Wahono SS, Lany L, Herminto W, Irawaty A, edi-
tors. Hot topics in paediatrics: Pediatri gawat darurat,
kardiologi anak, dan perinatologi. Naskah lengkap simposium
nasional Ikatan Dokter Anak Indonesia. Balikpapan: Badan
Penerbit Ikatan Dokter Anak Indonesia; 2006. p. 221-35.
14. Paul VK, Ramani AV. Newborn care at peripheral health
facilities. Indian J Pediatr 2000;67:378-82.
15. Bang AT, Bang RA, Baitule SB, Deshmukh MD, Reddy MH.
Burden of morbidities and unmet need for health care in
rural neonates: A prospective observational study in
Gadchiroli, India. Indian Pediatr 2001;38:952-65.
16. Bang AT, Bang RA, Reddy MH, Deshmukh MD. Methods
and the baseline situation in the field trial of home-based neo-
natal care in Gadchiroli, India. J Perinatol 2005;25:S11-7.
17. Bang AT, Reddy MH, Baitule SB, Deshmukh MD, Bang RA.
The incidence of morbidities in a cohort of neonates in rural
Gadchiroli, India. J Perinatol 2005;25: S18-28.
18. Brown DR, Kulter D, Rai B. Perinatal/neonatal clinical pre-
sentation: Bacterial concentration and blood volume re-
quired for a positive blood culture. J Perinatol 1995;15: 157-
159.
Published
2007-05-01
How to Cite
1.
Hafidh Y, Hidayah D, Sunyataningkamto S. Factors affecting mortality of neonatal sepsis in Moewardi Hospital, Surakarta. PI [Internet]. 1May2007 [cited 5Jan.2025];47(2):74-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/348
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Received 2016-08-25
Accepted 2016-08-25
Published 2007-05-01
Accepted 2016-08-25
Published 2007-05-01
