Main Article Content
69% of children globally and 43% oflndonesian children. Smoke
exposure during the developmental stage may affect cognitive
abilities, as measured by intelligence quotient (IQ). There have
been few studies conducted on the correlation of tobacco smoke
exposure to IQ. This is the first study of this type in Indonesia.
Objectives To assess the correlation between tobacco smoke
exposure and IQ in preschool children and to assess the correlation
between serum cotinine levels and IQ in preschool children
exposed to tobacco smoke.
Methods A cross-sectional study was conducted in the Tuminting
district, Manado in January - May 2011. Subjects were collected by
random sampling of 3-5 year-old children. In our study, 35 children
were deemed to have been exposed to tobacco smoke by serum
cotinine ~ 0.05 ng/ml and 25 children were deemed to not have
been exposed to tobacco smoke (cotinine < 0.05 ng/ml). Results
were analyzed by t-test and simple correlation analysis using SPSS
version 17 software with a significance level of P < 0.05.
Results There was a statistically significant difference in IQ
between the two groups, with mean IQ of 106.54 in the group
exposed to tobacco smoke and mean IQ of 109.36 in the group not
exposed to tobacco smoke (P=0.01). The mean serum cotinine
level in the group with tobacco smoke exposure was 1. 77 ng/mL.
There was no correlation between the mean level of cotinine and
mean IQ in this group (r = -0.19 and P=0.14).
Conclusions The mean IQ in the group with tobacco smoke
exposure was lower than that of the group not exposed to tobacco
smoke. There was no correlation between mean serum cotinine
level and mean IQ. [Paediatr lndones. 2012;52: 106-10].
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