Quality of life of children with acute lymphoblastic leukemia

Siti Arifah; Renu Pookboonmee; Autchareeya Patoomwan; Prasong Kittidumrongsuk; Mia Ratwita Andarsini

doi:10.14238/pi63.5.2023.405-10

Siti Arifah Nursing Department, Faculty of Health Science, Universitas Muhammadiyah, Surakarta, Central Java
Renu Pookboonmee School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok
Autchareeya Patoomwan School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok
Prasong Kittidumrongsuk Faculty of Public Health, Mahidol University, Bangkok
Mia Ratwita Andarsini Department of Pediatrics, Universitas Airlangga, East Java

DOI: https://doi.org/10.14238/pi63.5.2023.405-10

Keywords: acute lymphoblastic leukemia; cancer; children; quality of life

Abstract

Background Acute lymphoblastic leukemia (ALL) is the most common cancer in children worldwide, which requires long treatment. This condition and its subsequent treatment change the body's physiology, reducing children’s quality of life.

Objective To describe the quality of life in children with acute lymphoblastic leukemia in Java, Indonesia.

Methods This descriptive study with a cross-sectional approach included parents who had children with ALL at three referral hospitals in Java, Indonesia, between January 2021 and May 2022. We recruited 188 mothers or fathers who accompanied their children for follow-up visits or hospitalization. Children’s quality of life as the primary outcome was evaluated by parent proxy using the PedsQL 3.0 cancer module.

Results Most parents were mothers (81.9%); parents’ ages ranged from 22 to 59 years. The mean age of children was 7.63 (SD 3.85) years, with 63.3% boys and 147 (78.2%) treated in maintenance phase during the study. The mean overall children’s QoL score was 84.37 and it classified as high (73.9% of subjects), no children had very low QoL. The lowest mean sub-scale QoL score was in procedural anxiety (72.25), whereas the highest sub-scale score was in communication (91.56).

Conclusion There is an improvement in QoL of children with ALL in Indonesia. However, the procedural anxiety sub-scale requires more interventions to reduce anxiety and alleviate pain during invasive procedures.

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