Obesity and secondary sexual maturity in boys
Keywords:
obesity, boys, secondary sexual maturity, testicular volume
Abstract
Background Obesity induces earlier secondary sexual maturity in girls. However, results of studies in boys have been inconclusive.Objective To assess for an association between obesity and sexual maturity in boys.
Methods This was a prospective cohort study on 133 obese and 133 matched-for-age, non-obese, prepubertal boys, aged 9 to 10 years. They were observed every 4 months for a two year period. Obesity was defined as the BMI ≥the 95th percentile, according to the Centers for Disease Control 2000 growth charts. Secondary sexual maturity was defined as testicular volume of ≥4 mL and Tanner staging of pubic hair of ≥P2. Two trained nurses and a pediatric resident collected the data.
Results By the end of the study period, 106 (79.7%) obese boys had attained a testicular volume of 4 mL or more, vs. 85 (63.9%) non-obese boys (RR 1.78; 95%CI 1.19 to 2.67; P=0.004). Furthermore, 81 (60.9%) obese boys attained pubic hair states of Tanner stage P2 vs. 37 (27.8%) non-obese boys (RR 1.85 95%CI 1.46 to 2.34; P<0.001). The mean durations for achieving testicular volume of ≥4 mL were 21.25 (95%CI 20.75 to 21.74) months in obese boys and 22.26 (95%CI 21.80 to 22.72) months in non-obese boys (P=0.007). The mean durations for achieving Tanner stage P2 were 17.04 (95%CI 16.44 to 17.63) months in obese boys and 20.87 (95%CI 20.05 to 21.68) months in non-obese boys.
Conclusion Obesity is associated with earlier onset of sexual maturity in boys.
References
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2. Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, et al; on behalf of the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics—2011 update: a report from the American Heart Association. Circulation. 2011;123:e18 – e209.
3. Baker JL, Olsen LW, Sorensen Ti. Childhood body-mass index and the risk of coronary heart disease in adulthood. N Engl J Med. 2007;357:2329-37.
4. Wang Y. Is obesity associated with early sexual maturation? A comparison in American boys versus girls. Pediatrics. 2002;110:903-10.
5. Soetjiningsih, Ranuh IGN. Obesitas pada anak. In: Soetjiningsih, editor. Tumbuh kembang anak. Jakarta: EGC, 1995. p. 183-91.
6. Dick DM, Rose RJ, Viken RJ, Kaprio J. Pubertal timing and substance use: association between and within families across late adolescence. Am J Clin Nutr. 2000;36:180-9.
7. Biro FM, Lucky AW, Huster GA, Morrison JA. Pubertal staging in boys. J Pediatr. 1995; 127:100-2.
8. Lee JM, Kaciroti N, Appugliese D, Corwyn RF, Bradley RH, Lumeng JC. Body mass index and timing of pubertal initiation in boys. Arch Pediatr Adolesc Med. 2010;164:139-44.
9. Wirawan DS, Sadjimin T, Machfudz S. Pola perkembangan seksual sekunder siswa laki-laki sekolah dasar di Kotamadya Yogyakarta [master’s thesis]. [Yogyakarta]: Universitas Gadjah Mada; 2003.
10. Hartoyo E, Sadjimin T. Hubungan status gizi dengan pola perkembangan seksual sekunder pada siswa SLTP di Kotamadya Yogyakarta. [master’s thesis]. [Yogyakarta]: Universitas Gadjah Mada; 2002.
Published
2013-10-30
How to Cite
1.
Femina M, Julia M, Machfudz S. Obesity and secondary sexual maturity in boys. PI [Internet]. 30Oct.2013 [cited 23Dec.2024];53(5):283-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/307
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Received 2016-08-21
Accepted 2016-08-21
Published 2013-10-30
Accepted 2016-08-21
Published 2013-10-30
