Surveillance of rotavirus diarrhea
Keywords:
rotavirus, diarrhea, dehydration, G9 strain
Abstract
Background Rotavirus is a major cause of severe diarrhea anddehydration in children worldwide. Data on the burden of disease
in Indonesia is limited.
Objective To provide an epidemiological profile of rotavirus
infection among children hospitalized for diarrhea in Mohammad
Hoesin Hospital, Palembang.
Methods In January- December 2006, a prospective, hospitalbased
surveillance was carried out in children aged less than
five years, presenting with diarrhea. Stool samples were
examined for rotavirus using enzyme immunoassay (EIA).
G- and P-typing were performed on specimens confirmed to
be positive by EIA.
Results A total of 513 fecal specimens from 534 children were
tested for rotavirus. Rotavirus was detected in 64% of the
specimens, mostly of the G9 type (62.5%). Incidence ofrotavirus
diarrhea was highest in the 6 month to 2 years age group (60.4%).
Children with rotavirus diarrhea were more likely to present with
dehydration, compared to those with non-rotavirus diarrhea (94%
vs 70%, respectively, P=0.03).
Conclusion Rotavirus was the most common pathogen found
in children with diarrhea. Rotavirus was detected in 64% of
pediatric diarrheal specimens tested in our study. This finding
warrants the use of a large-scale program to prevent disease,
such as vaccination against rotavirus. [Paediatr lndones.
2012;52:22-7].
References
l. Parashar UD, Gibson CJ, Bresee JS, Glass RI. Rotavirus and
severe childhood diarrhea. Emerg Infect Dis. 2006; 12:304-6.
2. Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass
RI. Global ilness and death caused by rotavirus disease in
children. Emerg Infect Dis.2003 ;9:565-72.
3. Kim JS, Kang JO, Cho SC, Jang YT, Min SA, Park TH, et a l.
Epidemiological profile ofrotavirus infection in the Republic
of Korea: result from prospective surveillance in the Jeongeub
district, 1 July 2002 through 30 June 2004. J Infect Dis.
2005 ;l 92:S49-56.
4. Tate JE, Boshi-Pinto C, Steela AD, Duque J, Parashar UD. The
WHO-coordinated Global Rotavirus SuIVeillance Network 2008.
Estimation ofworldwiderotavirus-associated mortality in children
younger than 5 years before the introduction of universal rotavirus
vaccination programme: a systematic review and meta-analysis.
Lancet Infect Dis. 201l;Sl473-3099:70253-5.
5. Soriano-Gabarro M, Mrukowicz J, Vesikari T, Verstraeten
T. Burden of rotavirus disease in European union countries.
Pecliatr Infect Dis J. 2006;25: 7- 11.
6. Glass RI, Kilgore PE, Holman RC, Jin S, Smith JC, Woods
PA, et al. The epidemiology of rotavirus diarrhoea in the
United States: surveillance and estimates of disease burden.
J Infect Dis. 1996;174:S5-ll.
7. Grimwood K, Huang QS, Cohet C, Gosling IA, Hook SM, Teele
DW, et al. Rotavirus hospitalisation in New Zealand children
under 3 years of age. J Paediatr Child Health. 2006;42:196-203.
8. Chen KT, Chen PY, Tang RB, Huang YB, Lee PI, Yang JY,
et al. Sentinel hospital surveillance for rotavirus diarrhea in
Taiwan, 2001-2003. J Infect Dis. 2005; 192:S44-8.
9. Bresee JS, Fang ZY, Wang B, Nelson EA, Tam J, Soenarto
Y, et al. First report from the Asian rotavirus surveillance
network. Emerg Infect Dis. 2004;10:988-95.
10. Gentsch JR. Glass RI, Woods P, Gouvea, V, Gorziglia M, Flores J, et
al. Identification of group A rotavirus gene 4 types by polymerase
chain reaction. J Clin Microbiol. 1992;30: 1365-73.
11. Fang zy, Yang H, Zhang J, Ii YF, Hou AC, Ma L, et al. Child
rotavirus infection in association with acute gastroenteritis in
two Chinese sentinel hospitals. Pediatr Int. 2000;42:401-5.
12. Moe K, Hummelman EG, Oo W M, Lwin T, Htwe TT.
Hospital-based surveillance for rotavirus diarrhea in children
in Yangon, Myanmar. } Infect Dis. 2005;192:Slll-3.
13 . Hsu VP, Abdul Rahman H, Wong SL, Ibrahim LHJ, Yusoff
AFHJ, Chan LG, et al. Estimates of the burden of rotavirus
disease in Malaysia. J Infect Dis. 2005;192:S80-6.
14. Wilopo SA, Kilgore P, Kosen S, Soenarto Y, Aminah S, Cahyono
A, et al. Economic evaluation of a routine rotavirus vaccination
programme in Indonesia. Vaccine. 2009;27: F67-74.
15. Bishop RF, Unicomb LF, Soenarto Y, Suwardji H, Ristanto,
Barnes GL. Rotavirus serotypes causing acute diarrhea in
hospitalized children in Yogyakarta, Indonesia during 1978
- 1979. Arch Virol. 1989;107:207- 13.
16. Wilopo SA, Soenarto Y, Bresee JS, Tholib A, Aminah S,
Cahyono A, et al. Rotavirus surveillance to determine disease
burden and epidemiology in Java, Indonesia, August 2001
through April 2004. Vaccine. 2009;27:F61-6.
17. Putnam SD, Sedyaningsih ER, Listiyaningsih E, Pulungsih SP,
Komalarini, Soenarto Y, et al. Group A rotavirus-associated
diarrhea in children seeking treatment in Indonesia. J Clin
Virology. 2007;40:289-94.
18. Kilgore PE, Unicomb LE, Gentsch JR, Albert MJ, McElroy
CA, Glass RI. Neonatal rotavirus infection in Bangladesh:
strain characterization and risk factors for n osocomial
infection. Pediatr Infect Dis J. 1996;15:672-7.
19. WHO. Rotavirus vaccine. W kly Epidemiol Rec. 2007;
82:285-95.
20. Simpson E, WittetS, Bonilla ], Gamazina K, Cooley L, Winkler
JL. Use of formative research in developing a knowledge
translation approach to rotavirus vaccine introduction in
developing countries. BMC Public Health. 2007;7:281.
21. Van Damme P, Van der Wielen M, Ansaldi F, Desgrandchamps
D, Domingo JD, Sanchez FG, et al. Rotavirus vaccines:
considerations for successful implementation in Europe.
Lancet. 2006;6:805-12.
severe childhood diarrhea. Emerg Infect Dis. 2006; 12:304-6.
2. Parashar UD, Hummelman EG, Bresee JS, Miller MA, Glass
RI. Global ilness and death caused by rotavirus disease in
children. Emerg Infect Dis.2003 ;9:565-72.
3. Kim JS, Kang JO, Cho SC, Jang YT, Min SA, Park TH, et a l.
Epidemiological profile ofrotavirus infection in the Republic
of Korea: result from prospective surveillance in the Jeongeub
district, 1 July 2002 through 30 June 2004. J Infect Dis.
2005 ;l 92:S49-56.
4. Tate JE, Boshi-Pinto C, Steela AD, Duque J, Parashar UD. The
WHO-coordinated Global Rotavirus SuIVeillance Network 2008.
Estimation ofworldwiderotavirus-associated mortality in children
younger than 5 years before the introduction of universal rotavirus
vaccination programme: a systematic review and meta-analysis.
Lancet Infect Dis. 201l;Sl473-3099:70253-5.
5. Soriano-Gabarro M, Mrukowicz J, Vesikari T, Verstraeten
T. Burden of rotavirus disease in European union countries.
Pecliatr Infect Dis J. 2006;25: 7- 11.
6. Glass RI, Kilgore PE, Holman RC, Jin S, Smith JC, Woods
PA, et al. The epidemiology of rotavirus diarrhoea in the
United States: surveillance and estimates of disease burden.
J Infect Dis. 1996;174:S5-ll.
7. Grimwood K, Huang QS, Cohet C, Gosling IA, Hook SM, Teele
DW, et al. Rotavirus hospitalisation in New Zealand children
under 3 years of age. J Paediatr Child Health. 2006;42:196-203.
8. Chen KT, Chen PY, Tang RB, Huang YB, Lee PI, Yang JY,
et al. Sentinel hospital surveillance for rotavirus diarrhea in
Taiwan, 2001-2003. J Infect Dis. 2005; 192:S44-8.
9. Bresee JS, Fang ZY, Wang B, Nelson EA, Tam J, Soenarto
Y, et al. First report from the Asian rotavirus surveillance
network. Emerg Infect Dis. 2004;10:988-95.
10. Gentsch JR. Glass RI, Woods P, Gouvea, V, Gorziglia M, Flores J, et
al. Identification of group A rotavirus gene 4 types by polymerase
chain reaction. J Clin Microbiol. 1992;30: 1365-73.
11. Fang zy, Yang H, Zhang J, Ii YF, Hou AC, Ma L, et al. Child
rotavirus infection in association with acute gastroenteritis in
two Chinese sentinel hospitals. Pediatr Int. 2000;42:401-5.
12. Moe K, Hummelman EG, Oo W M, Lwin T, Htwe TT.
Hospital-based surveillance for rotavirus diarrhea in children
in Yangon, Myanmar. } Infect Dis. 2005;192:Slll-3.
13 . Hsu VP, Abdul Rahman H, Wong SL, Ibrahim LHJ, Yusoff
AFHJ, Chan LG, et al. Estimates of the burden of rotavirus
disease in Malaysia. J Infect Dis. 2005;192:S80-6.
14. Wilopo SA, Kilgore P, Kosen S, Soenarto Y, Aminah S, Cahyono
A, et al. Economic evaluation of a routine rotavirus vaccination
programme in Indonesia. Vaccine. 2009;27: F67-74.
15. Bishop RF, Unicomb LF, Soenarto Y, Suwardji H, Ristanto,
Barnes GL. Rotavirus serotypes causing acute diarrhea in
hospitalized children in Yogyakarta, Indonesia during 1978
- 1979. Arch Virol. 1989;107:207- 13.
16. Wilopo SA, Soenarto Y, Bresee JS, Tholib A, Aminah S,
Cahyono A, et al. Rotavirus surveillance to determine disease
burden and epidemiology in Java, Indonesia, August 2001
through April 2004. Vaccine. 2009;27:F61-6.
17. Putnam SD, Sedyaningsih ER, Listiyaningsih E, Pulungsih SP,
Komalarini, Soenarto Y, et al. Group A rotavirus-associated
diarrhea in children seeking treatment in Indonesia. J Clin
Virology. 2007;40:289-94.
18. Kilgore PE, Unicomb LE, Gentsch JR, Albert MJ, McElroy
CA, Glass RI. Neonatal rotavirus infection in Bangladesh:
strain characterization and risk factors for n osocomial
infection. Pediatr Infect Dis J. 1996;15:672-7.
19. WHO. Rotavirus vaccine. W kly Epidemiol Rec. 2007;
82:285-95.
20. Simpson E, WittetS, Bonilla ], Gamazina K, Cooley L, Winkler
JL. Use of formative research in developing a knowledge
translation approach to rotavirus vaccine introduction in
developing countries. BMC Public Health. 2007;7:281.
21. Van Damme P, Van der Wielen M, Ansaldi F, Desgrandchamps
D, Domingo JD, Sanchez FG, et al. Rotavirus vaccines:
considerations for successful implementation in Europe.
Lancet. 2006;6:805-12.
Published
2012-03-30
How to Cite
1.
Widowati T, Soenarto Y, Bakrie A, Nirwati H. Surveillance of rotavirus diarrhea. PI [Internet]. 30Mar.2012 [cited 22Nov.2024];52(1):22-7. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/294
Section
Articles
Authors who publish with this journal agree to the following terms:
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
Received 2016-08-21
Accepted 2016-08-21
Published 2012-03-30
Accepted 2016-08-21
Published 2012-03-30
