BCG as Diagnostic Test for Primary Tuberculosis in Children

  • Widiatmodjo Widiatmodjo Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Yati Soenarto Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Budi Susatyo Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Sunartini Iman Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Sulistyowati Sulistyowati Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Ismangoen Ismangoen Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
DOI: https://doi.org/10.14238/pi23.1-2.1983.7-14
Keywords: BCG, PPD, Mantoux intradermal test, primary tuberculosis, vaccination

Abstract

BCG and PPD Mantoux Intradermal Test were done simultaneously on 35 children suffering from primary tuberculosis hospitalized in the Department of Child Health, School of Medicine, Gajah Mada University, Yogyakarta, Indonesia, during the period of June 1980 to November 1980.

This study revealed that: The BCG test was almost three times (74.3%) more sensitive than the PPD Mantoux Intradermal test in children suffering from primary tuberculosis. In under-nourished children with tuberculosis, the BCG test was even more sensitive (85.0% : 25.0%) and this difference was statistically significant (P < 0.01).

There was a high frequency of false negative tuberculine reaction (74.3%) and accelerated BCG reaction (74.3%) in primary tuberculosis. It is suggested that BCG test be used as a diagnostic test as well as prophylactic in tuberculosis children who have had a BCG vaccination.

Author Biography

Sunartini Iman, Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java

Sulistyowati; Ismangoen

References

1. CHOUDHRY, V.P.; SINGH, M.M. and ISHWAR, C.V.: BCG and Mantoux intradermal test in the diagnosis of tuberculosis. Indian Paediatr. 11 : 8 (1974).
2. FRIEDMANN, E. and SILVERMAN, I.: Use of BCG vaccine as a new diagnostic test for tuberculosis. Pediatrics 9 : 280 (1952).
3. LOTHE, P.S.; GUPTA, S.P. and AGARWAL, S.P.: Evaluation of BCG as a diagnostic test in the diagnosis of tuberculous meningitis. Indian Pediatr. 10 : 7 (1973).
4. RAHAJOE, N.N. : Problematik klinik tuberkulosis anak. Berita Klinik I.D.A.I. Cabang Jakarta, 29 Juni 1975.
5. SUTARJO, J. and IBRAHIM, I.: Direct BCG vaccination in Primary School children with various doses of freeze dried BCG vaccine (first communication). Bull. Bio Farma VIII : 1, 43 - 69 (1971).
6. SUT ARJO, J. and IBRAHIM, I. : Direct BCG vaccination in young infants with various doses of freeze dried BCG vaccine (final communication) . Bull. Bio Farma 10 : 16 - 32 (1973).
7. UDANI, P.M.; PARIKH, U.C.; SHAH, P.M. and NAIKH, P.A.: BCG test in tuberculosis. Indian Paediatr. 8 : 143 (1971).
8. UETVEDT, H.J.; AANONSEN, A. : Diagnostic BCG test. Acta Tuberc. Scand., 23 : 1 (1949) .
9. YATI; SURJONO, A.; ISMAIL, D.; SUNARTINI dan SUTARYO: Tuberkulosis paru pada anak. Almanak Kesehatan (1976).
Published
2021-12-20
How to Cite
1.
Widiatmodjo W, Soenarto Y, Susatyo B, Iman S, Sulistyowati S, Ismangoen I. BCG as Diagnostic Test for Primary Tuberculosis in Children. PI [Internet]. 20Dec.2021 [cited 21Dec.2024];23(1-2):7-4. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2889
Issue
Vol 23 No 1-2 (1983): January - February 1983
Section
Pediatric Respirology

Copyright (c) 2021 Widiatmodjo Widiatmodjo, Yati Soenarto, Budi Susatyo, Sunartini Iman, Sulistyowati Sulistyowati, Ismangoen Ismangoen

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Received 2021-12-20
Published 2021-12-20