BCG as Diagnostic Test for Primary Tuberculosis in Children

  • Widiatmodjo Widiatmodjo Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Yati Soenarto Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Budi Susatyo Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Sunartini Iman Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Sulistyowati Sulistyowati Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
  • Ismangoen Ismangoen Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java
Keywords: BCG, PPD, Mantoux intradermal test, primary tuberculosis, vaccination

Abstract

BCG and PPD Mantoux Intradermal Test were done simultaneously on 35 children suffering from primary tuberculosis hospitalized in the Department of Child Health, School of Medicine, Gajah Mada University, Yogyakarta, Indonesia, during the period of June 1980 to November 1980.

This study revealed that: The BCG test was almost three times (74.3%) more sensitive than the PPD Mantoux Intradermal test in children suffering from primary tuberculosis. In under-nourished children with tuberculosis, the BCG test was even more sensitive (85.0% : 25.0%) and this difference was statistically significant (P < 0.01).

There was a high frequency of false negative tuberculine reaction (74.3%) and accelerated BCG reaction (74.3%) in primary tuberculosis. It is suggested that BCG test be used as a diagnostic test as well as prophylactic in tuberculosis children who have had a BCG vaccination.

Author Biography

Sunartini Iman, Department of Child Health, Universitas Gadjah Mada Medical School, Yogyakarta, Central Java

Sulistyowati; Ismangoen

References

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Published
2021-12-20
How to Cite
1.
Widiatmodjo W, Soenarto Y, Susatyo B, Iman S, Sulistyowati S, Ismangoen I. BCG as Diagnostic Test for Primary Tuberculosis in Children. PI [Internet]. 20Dec.2021 [cited 22Feb.2024];23(1-2):7-4. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2889
Section
Pediatric Respirology
Received 2021-12-20
Published 2021-12-20