Oral Rehydration Solution: An Appropriate Formula for Acute Infantile Diarrhoea

  • Sunoto Sunoto Department of Child Health, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta
  • Suharyono Suharyono Department of Child Health, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta
  • Suryono Wibowo Department of Child Health, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta
  • Wibowo Wibowo Department of Child Health, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta
Keywords: ral rehydration solution, acute infantile diarrhoea, rehydration

Abstract

A new formula of oral rehydration solution (kristalyte R) with the following composition: Na 51.2, K 25.0, C/ 37.5, Citrate 57.5 mEq/L, dextrose 100 and sucrose 52.0 mMol/L with the osmolality of 323 mOsm/L were tried in 21 acute infantile gastroenteritis with mild and moderate dehydration. The age of the patients varied from 2.5 to 36 months with the average of 13.4 months.

As a control were used 21 children with the same age, same diagnosis and same nutritional state treated with oralyte with the composition of Na 90, K 15, Cl 75, HC03 30 mEq/L and glucose 120 mMol/L with the osmolality of 330 mOsm/L.

Clinical observation and chemical observation were done before and after rehydration which usually occurred after 24 hours of treatment.

Stool culture, W BC count and urinalysis were done on admission only.

The results of the trial revealed that in kristalyte group better results were obtained in gaining the body weight, reducing the frequency of diarrhoea or fluid loss, acceptance of the solution and reducing the risk of periorbital oedema.

No hypernatremia and neurological manifestations were found in both groups and all of the children were discharged on the third day in good condition.

Author Biography

Suryono Wibowo, Department of Child Health, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta

Sumarso

References

1. BACHTIN, M.; NELWAN; SUPRAPTO; TELUK SEBODO and ISMANGOEN : The use of Antibiotics in Childhood Diarrhea. Presented at. the Second Asian Congress or Pediatrics Jakarta 3-6 August 1976.
2. BROTOWASISTO; T. GINTING'; RUDJITO; ANWAR BUNASAR and SUDARMAN: Evaluation of the Results of the Rehydration Programme (1974-1978). Second Seminar on Rehydration, Jakarta 14 - 18 November 1978.
3. CHAKRABARTI, G.C; S. K. D. E. B. ROY and S. CHAKRABARTI : Treatment of Small Bowel Diarrhea with Electrolyte Glucose Drink. Indian Pediatr. 13: 517 (1976).
4. HIRSCHHORN, M; CASH, R;A.; WOODWARD, W.A. arid SPIVEY. C.H. : Oral Fluid Therapy of Apache Children with Acute Infectious Diarrhea. Lancet ii : 15 (1972).
5. HIRSCHHORN, N.; CAR THY, B.J.; RANNEY, B.; HIRSCHHORN, M.A.; WOODWARD, S.T.; LACAPA, A.; CASH, R.A. and WOODWARD, W.A.: Ad Libitum Oral Glucose Electrolyte Therapy for Acute Diarrhoea in Apache Children. J. Pediatr. 83 : 562 (1973).
6. HIRSCHHORN, N. and WESLEY T.A: Oral Rehydration of Children with Acute Diarrhoea. Lancet i : 494 (1972 .
7. KING, M. : Gastroenteteritis of Infants. Presented at the First Seminar on Rehydration, Jakarta 26 - 29 August 1974.
8. LUDAN, A.C. and DEL MUNDO, Y.: The Efficiency of Electrolyte Fluid in the Therapy of Diarrhea. J. Phillip. Med. Ass. 49 : 243 (1973).
9. MUNGINAH, P.A.; SUPRAPTO; YATI SUNARTO; M. BACHTIN; M.S. SUTRlSNO; SUTARTO and ROHDE, J.E.: Sucrose Electrolyte Solution ,for oral Rehydration in Diarrhea. Presented at the 5th Asian Pacific Congress of -Gastrenterology, Singapore 23 - 29 May 1976.
10. NAIK, N.Y. and SHAH, P.M. : Oral Rehydration in Acute Gastroenteritis in young Children. Indian Paediatr. 13 : 127 (1976).
11. NALIN, D.R. : Sucrose in Oral Therapy of Cholera and related diarrhoeas. Lancet ii : 1400 (1975).
12. NALIN, D.R.; CASH, R.A. and RAHMAN, M. : Oral (Nasogastric) Maintenance Therapy for Cholera Patients in all Age Group. Bull. WHO 43 : 361 (1970).
13. PIERCE, N.F. : - Recent Advances in Pathogenesis of Diarrhoeal Diseases in Relation to Treatment and Prevention. Presented at the Second National Indonesian Pediatric Congress, · Bandung 21 - 25 April 1971. Pediatr. Indones. 12 : 470 (1972). Assigment Report on Rehydration Practices and Training in the Management of Infantile Diarrhea and Cholera in Indonesia. WHO-SEARO Rep. Ser Sept. (1973).
14. PITONO SUPARTO; ISMUDIYANTO; M.S. SUBIYANTO; BING RUDIYANTO and BUDHIANTO SUHADI : Modified Oral Electrolyte Solution for Infantile Diarrhoea. Presented at the 5th Asian Pacific Congress of Gastroenterobgy, Singapore 23 - 29 May 1976.
15. ROHDE, J.E. : Rehydration in the Field. Presented at the Seminar on Rehydration, Jakarta· 26-29 August 1974. Pediatr. Indones. 14 : 148 (1Q74).
16. SUHARYONO; ADNAN S.W. , and R, SUTEJO : Rehydration Center in the OPD Child Health University of Indonesia, during a short cholera outbreak after floods in Jakarta 8-15 Februari 1976. Paediatr. Indones. 17: 218 (19771.
17. SUNOTO; HERMAN PIOH; ADNAN S. WIHARTA and SUHARYONO : An Oral Electrolyte Solution (Pedialyte) in the Treatment of Acute Infantile Gastroenteritis. Presented at the 5th Scientific Meeting of the Coordinating Board of Indonesian Paediatric Gastroenterology, Parapat, North Sumatera, 9-12 December 1977, Paediatr. Indones. 18:199 - 208 (1978).
18. SUNOTO; TITUT S. PUSPONEGORO; SUSILO SURACHMAD and W.R. SANBORN : Treatment of Acute Infantile Gastroenteritis, Presented at the 5th Asian Pacific Congress of Gastroenterology, Singapore 23-29 May 1976.
19. SUNOTO, TITUT S. PUSPONEGORO; SURIDWAN and W. R. SANBORN: A Question of the use of Antibiotics in the Treatment of Acute Infantile Gastroenteritis. Paediatr. Indones. 18: 191 (1978).
Published
2021-12-16
How to Cite
1.
Sunoto S, Suharyono S, Wibowo S, Wibowo W. Oral Rehydration Solution: An Appropriate Formula for Acute Infantile Diarrhoea. PI [Internet]. 16Dec.2021 [cited 3Jul.2024];20(9-10):205-5. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2881
Section
Pediatric Gastrohepatology
Received 2021-12-16
Published 2021-12-16