Trichuris dysentery syndrome, the neglected tropical disease: a case series

  • Yulia Fatma Wardani Department of Child Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Central Java
  • Ida Safitri Laksono Department of Child Health, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Central Java
  • Teti Adriana Lubis Scholoo Keyen Hospital, Sorong Selatan, Papua Barat
Keywords: trichuris dysentery syndrome; tropical disease; soil transmitted helminths; bloody diarrhea, iron deficiency anemia


Almost 2 billion people, about a quarter of the world’s population, are infected with soil-transmitted helminths (STH) worldwide. Approximately 270 million preschool children and more than 550 million school-age children live in areas of extensive parasite transmission.1,2 Indonesia is a moderate-to-high-risk area of STH, with an overall mean prevalence of 28.12%. However, the prevalence in Papua is higher.3 A study reported that 50% of school-aged children in Jayapura, Papua, a high-risk area, suffered from STH, with distributions of 48.5% Ascaris lumbricoides, 28.6% Trichuris trichiura, 14.3% hookworm, and 8.6% mixed infection.4 


1. WHO. Guideline: Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups. Geneva: World Health Organization; 2017
2. Schulz JD, Moser W, Hürlimann E, Keiser J. Preventive chemotherapy in the fight against soil-transmitted helminthiasis: achievements and limitations. Trends Parasitol. 2018;34:590–602. DOI: 10.1016/
3. Badan Litbangkes Kemenkes RI. Laporan Nasional RISKESDAS 2017. Jakarta: Kemenkes RI; 2017.
4. Martila M, Sandy S, Paembonan N. Hubungan higiene perorangan dengan kejadian kecacingan pada murid SD Negeri Abe Pantai Jayapura. J Plasma. 2016;1:87–96. DOI : 10.22435/plasma.v1i2.4538.87-96.
5. Kaminsky RG, Castillo RV, Flores CA. Growth retardation and severe anemia in children with Trichuris dysenteric syndrome. Asian Pac J Trop Biomed. 2015;5:591–7. DOI: 10.1016/j.apjtb.2015.05.005.
6. Noorizan AM, Raj SM. Trichuris dysentery syndrome?: evidence that it may be underdiagnosed in Kelantan. Med J Malaysia. 2001;56:53–7. PMID: 11503297.
7. Khuroo MS, Khuroo MS, Khuroo NS. Trichuris dysentery syndrome?: a common cause of chronic iron deficiency anemia in adults in an endemic area (with videos). Gastrointest Endosc. 2010;71:200–4. DOI: 10.1016/j.gie.2009.08.002.
8. Brooker SJ. Soil-transmitted helminth treatment: multiple drug regimens. Lancet Infect Dis. 2018;18:698–9. DOI: 10.1016/S1473-3099(18)30268-8.
9. WHO Working group on Soil-transmitted helminthiasis. Monitoring anthelmintic efficacy for soil transmitted helminths (STH). 2008. (cited 2020 February 20) Available from:
10. Agarwal A. Pica- an enigma of malnutrition. J Nutr Disord Ther. 2017;07:7–8. DOI: 10.4172/2161-0509.1000e132.
11. WHO. WHO Global Nutrition Targets 2025: Stunting Policy Brief [Internet]. Genewa, Swiss; 2014 [cited 2019 Jun 27]. Available from:
12. Anto EJ, Nugraha SE. Efficacy of albendazole and mebendazole with or without levamisole for ascariasis and trichuriasis. Open Access Maced J Med Sci. 2019;7:1299–302. DOI: 10.3889/oamjms.2019.299.
13. Knopp S, Mohammed KA, Speich B, Hattendorf J, Khamis IS, Khamis AN, et al. Albendazole and mebendazole administered alone or in combination with ivermectin against Trichuris trichiura: a randomized controlled trial. Clin Infect Dis. 2010;51:1420–8. DOI: 10.1086/657310.
How to Cite
Wardani Y, Laksono I, Lubis T. Trichuris dysentery syndrome, the neglected tropical disease: a case series. PI [Internet]. 11Oct.2022 [cited 30Nov.2023];62(6):430-. Available from:
Case Report
Received 2021-01-25
Accepted 2022-10-11
Published 2022-10-11