Renal manifestations in tuberous sclerosis patients: two case reports

Main Article Content

Oke Rina Ramayani
Rosmayanti Rosmayanti
Rafita Ramayati
Rusdidjas Rusdidjas

Abstract

Tuberous sclerosis (TS) is a neurocutaneous disorder, characterized by
mental retardation, epilepsy, and facial
angiofibromas. The incidence has been
estimated to be 1 case per 6000 live births.
Although rare, this disorder is a cause of mental
retardation with severe epilepsy.1 Scientists have
found manifestations of this disorder not only in
brain and skin, but also in the eyes, heart, lungs, and
kidneys, so it has been renamed tuberous sclerosis
complex (TSC).

Article Details

How to Cite
1.
Ramayani O, Rosmayanti R, Ramayati R, Rusdidjas R. Renal manifestations in tuberous sclerosis patients: two case reports. PI [Internet]. 28Feb.2013 [cited 24Jan.2020];53(1):56-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/250
Section
Articles
Received 2016-08-18
Accepted 2016-08-18
Published 2013-02-28

References

1. Leung AKC, Robson WLM. Tuberous sclerosis complex: a
review. J Pediatr Health Care. 2007;21:108-14.
2. Roach ES, Sparagana SP. Diagnosis of tuberous sclerosis
complex. J Child Neurol. 2004; 19:643-9.
3. Schillinger F, Montagnac R. Chronic renal failure and its
treatment in tuberous sclerosis. Nephrol Dial Transplant.
1996;11:481-5.
4. Au KS, Williams AT, Gambello MJ, Northtrup H. Molecular
genetic basis of tuberous sclerosis complex: from bench to
bedside. J Child Neurol. 2004; 19:699-709.
5. Rakowski SK, Winterkom EB, Paul E, Steele DJ, Halpern
EF, Thiele EA. Renal manifestations of tuberous sclerosis
complex: incidence, prognosis, and predictive factors. Kidney
Int. 2006;70: 1777-82.
6. Bissler JJ, Kingswood JC. Renal angiomyolipomata. Kidney
Int. 2004;66:924-34.
7. Casper KA, Donnelly LF, Chen B. Tuberous sclerosis complex:
renal imaging findings. Radiology. 2002;225:451-6.
8. Zimmerhackl LB, Rehm M, Kaufmehl K, Kurlemann G,
Brandis M. Renal involvement in tuberous sclerosis complex:
a retrospective survey. Pediatr N ephrol. 1994;8 :451-7.
9. Narla LD, Slovis TL, Watts FB, Nigro M. The renal lesions of
tuberosclerosis (cysts and angiomyolipomia) screening with
sonography and computerized tomography. Pediatr Radio!.
1988;18:205-9.
10. Brodkiewickz A, Marciniak H, Szychot E, Walecka A,
Peregud-Pogorzelski J. Angiomyolipomas, renal manifestation
of tuberous sclerosis complex in 1 7 year old boy a case report.
Ann Acad Med Stetin. 2008;54:160-5.