The efficacy of sulphate quinine compared to fansidar in treating falciparum malaria in children 6 months – 7 years old

Authors

  • M. Mogi Department of Child Health, Universitas Sam Ratulangi Medical School/Gunung Wenang Hospital, Manado, North Sulawesi
  • T. H. Rampengan Department of Child Health, Universitas Sam Ratulangi Medical School/Gunung Wenang Hospital, Manado, North Sulawesi
  • T. H. Rampengan Department of Child Health, Universitas Sam Ratulangi Medical School/Gunung Wenang Hospital, Manado, North Sulawesi

Keywords:

falciparum malaria; sulphate quinine; fansidar; sulphadozine pyrimethamine; sulphadoxine; infection

Abstract

From January 1989 until February 1990, 65 children suffering from falciparum malaria without complikation at the Department of Child Health Medical School Sam Ratulangi University/Gunung Wenang Hospital Manada were randomly allocated into 2 groups. The first group was treated with sulphate quinine based on the dose of 30 mg/kgbw/day in 3 divided doses and the other one was treated with single dose fansidar (sulphadoxine-pyrimethamine) based on the dose of sulphadoxine 20-30 mg/kgbw/day. The group treated with quinine showed much shorter duration of parasitemia compared with the group treated with fansidar.

Fever subsided more rapidly in children treated with quinine compared with those treated with fansidar.

References

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Published

2020-06-05

How to Cite

1.
Mogi M, Rampengan TH, Rampengan TH. The efficacy of sulphate quinine compared to fansidar in treating falciparum malaria in children 6 months – 7 years old. PI [Internet]. 2020Jun.5 [cited 2025May3];31(3-4):104-10. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2429

Issue

Vol. 31 No. 3-4 (1991): March - April 1991

Section

Infection & Tropical Pediatrics

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