Comparative efficacy study of combination fansidar-sulphate-quinine and fansidar-hcl-tetracycline in falciparum malaria in children above 7 years old

Main Article Content

K. Silitonga
T. H. Rampengan

Abstract

The objective of this study is to compare the results of treatment of children with falciparum malaria with the combinations of fansidar-su/phate quinine and fansidar-chlortetracycline as an alternative treatment of chloroquine'resistant falciparum malaria.


This study was carried out prospectively on 45 cases with the age equal or above 7 years, who had been admitted in the Pediatric Department, Gunung Wenang Hospital, Manado, during the period of January 1989- December 1989. Twenty three cases had been treated with fansidar - sulphate quinine and 22 cases with fansidar-chlortetracycline, all of them underwent blood examinations for malaria for 7 consecutive days (day 0-8).


Asexual parasitemia and fever in the fansidar-sulphate quinine group significantly disappeared more rapidly than in the fansidar-chlortetracycline group (P <0.03 and <0.005). There occurred neither drug resistance nor serious side effect in both groups.

Article Details

How to Cite
1.
Silitonga K, Rampengan TH. Comparative efficacy study of combination fansidar-sulphate-quinine and fansidar-hcl-tetracycline in falciparum malaria in children above 7 years old. PI [Internet]. 5Jun.2020 [cited 13Aug.2020];31(3-4):111-. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2427
Section
Infection & Tropical Pediatrics
Received 2020-06-05
Published 2020-06-05

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