The role of clinical diagnostic criteria for anti-N-methyl-D-aspartate receptor encephalitis in children: A case report

  • Irawan Mangunatmadja Neurology Division Department of Child Health, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia.
  • Ricca Fauziyah
  • Achmad Rafli Department of Child Health, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National Hospital, Jakarta, Indonesia.
Keywords: encephalitis, anti-NMDAR, anti-N-methyl-D-aspartate receptor


Encephalitis is a neurological disorder that develops rapidly into a progressive encephalopathy caused by inflammatory processes in the brain. The incidence of encephalitis in developed countries is 5-10 per 100,000 per year. Encephalitis can affect all ages and cause long-term effects on patients, their families, and society.1-3 Autoimmune encephalitis, including anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, is increasingly recognized as a cause of encephalitis in children and has a considerable mortality rate of 5-7%.Physicians should suspect anti-NMDAR encephalitis in patients with prominent neuropsychiatric symptoms and movement disorder.1-3 We report here a case of anti-NMDAR encephalitis and discuss the role of clinical criteria in diagnosing anti-NMDAR encephalitis in children.


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How to Cite
Mangunatmadja I, Fauziyah R, Rafli A. The role of clinical diagnostic criteria for anti-N-methyl-D-aspartate receptor encephalitis in children: A case report. PI [Internet]. 5Jan.2022 [cited 21Apr.2024];62(1):66-1. Available from:
Case Report
Received 2020-05-19
Accepted 2022-01-05
Published 2022-01-05