Acid-Base Balance and Blood-Gas Analysis in Bronchopneumonia in Infancy and Childhood

  • Mardjanis Said Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • I. Boediman Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Nastiti N. Rahajoe Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
  • Noenoeng Rahajoe Department of Child Health, Universitas Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta
Keywords: acid base balance; blood gas analysis; bronchopneumonia

Abstract

Arterial Blood-Gas and pH changes were studied in sixty-three infants and children aged 6 years or less, with severe and uncomplicated bronchopneumonia, which was proven clinically and radiologically.

Fifty-five (87.3%) patients showed a ventilatory insufficiency (PaC02 below 35 mmHg). Only 3 (4.8%) cases were found with carbon retention as a sign of ventilatory failure (PaC02 above 45 mmHg). Twenty-eight (44.4%) cases had metabolic component. The suggested causes of metabolic acidosis in these cases were the inflammatory process in the lungs itself which caused hypoxia, and a low intake during their sickness prior to admission to the hospital.

References

1. ASTRUP, P., SIGAARD- ANDERSEN, 0., JORGENSES, K. and ENGEL, K. : The Acid-base metabolism. A new approach. Lancet i : 1035 - 1039 (1950).
2. HUCKABEE, W.O. : Relationships of pyruvate and lactate during anaerobic metabolism. III. Effect of breathing lowoxygen gases. J. Clin. Invest. 37 : 264-271 ( J 958).
3. MORRISON, B. : Anoxia in the Acute Respiratory infections of childhood. Its recognition and treatment. Lancet ii : 737 - 740 (1955).
4. RACHMAT SADELI, I. BOEDIMAN, MARDJANIS SAID, ALIAMRAN RASJID and M.H. SIBARANI : Bronchopulmonary disease and measle. The clinical and radiological aspects. IVth National Congress of Pediatrics, Yogyakarta (1978).
5. REYNOLDS, E.O.R. : The effect of breathing 40 percent oxygen on the arterial blood gas tensions of babies with bronchiolitis. J. Pediatr. 63 : 1135- 1139 (1963).
6. SHAPIRO, B.A. : The clinical application of Blood gases. Year Book Medical Publishers Inc. Chicago (1976).
7. SIMPSON, H. : Unpublished. Cited by Simpson and Flenley (1976) .
8. SIMPSON, H. and FLENLEY, D.C. : Arterial blood-gas tensions and pH in Acute Lower Respiratory Tract Infections in Infancy and Childhood. Lancet ii : 7- 12 (1967).
Published
2019-09-20
How to Cite
1.
Said M, Boediman I, Rahajoe N, Rahajoe N. Acid-Base Balance and Blood-Gas Analysis in Bronchopneumonia in Infancy and Childhood. PI [Internet]. 20Sep.2019 [cited 6Feb.2025];20(3-4):68-6. Available from: https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2321
Issue
Vol 20 No 3-4 (1980): March - April 1980
Section
Pediatric Respirology

Copyright (c) 2019 Mardjanis Said, I. Boediman, Nastiti N. Rahajoe, Noenoeng Rahajoe

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Received 2019-09-20
Published 2019-09-20